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138 related items for PubMed ID: 1728313

  • 1. Origin and fate of iron mobilized by the 3-hydroxypyridin-4-one oral chelators: studies in hypertransfused rats by selective radioiron probes of reticuloendothelial and hepatocellular iron stores.
    Zevin S, Link G, Grady RW, Hider RC, Peter HH, Hershko C.
    Blood; 1992 Jan 01; 79(1):248-53. PubMed ID: 1728313
    [Abstract] [Full Text] [Related]

  • 2. ICL670A: a new synthetic oral chelator: evaluation in hypertransfused rats with selective radioiron probes of hepatocellular and reticuloendothelial iron stores and in iron-loaded rat heart cells in culture.
    Hershko C, Konijn AM, Nick HP, Breuer W, Cabantchik ZI, Link G.
    Blood; 2001 Feb 15; 97(4):1115-22. PubMed ID: 11159545
    [Abstract] [Full Text] [Related]

  • 3. IRC011, a new synthetic chelator with selective interaction with catabolic red blood cell iron: evaluation in hypertransfused rats with hepatocellular and reticuloendothelial radioiron probes and in iron-loaded rat heart cells in culture.
    Rivkin G, Link G, Simhon E, Cyjon RL, Klein JY, Hershko C.
    Blood; 1997 Nov 15; 90(10):4180-7. PubMed ID: 9354689
    [Abstract] [Full Text] [Related]

  • 4. Exploring the "iron shuttle" hypothesis in chelation therapy: effects of combined deferoxamine and deferiprone treatment in hypertransfused rats with labeled iron stores and in iron-loaded rat heart cells in culture.
    Link G, Konijn AM, Breuer W, Cabantchik ZI, Hershko C.
    J Lab Clin Med; 2001 Aug 15; 138(2):130-8. PubMed ID: 11477380
    [Abstract] [Full Text] [Related]

  • 5. Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: studies in rat heart cells in culture.
    Hershko C, Link G, Pinson A, Peter HH, Dobbin P, Hider RC.
    Blood; 1991 May 01; 77(9):2049-53. PubMed ID: 2018841
    [Abstract] [Full Text] [Related]

  • 6. Determinants of fecal and urinary iron excretion in desferrioxamine-treated rats.
    Hershko C.
    Blood; 1978 Mar 01; 51(3):415-23. PubMed ID: 623907
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of 2-amido-3-hydroxypyridin-4(1H)-ones: novel iron chelators with enhanced pFe3+ values.
    Liu ZD, Piyamongkol S, Liu DY, Khodr HH, Lu SL, Hider RC.
    Bioorg Med Chem; 2001 Mar 01; 9(3):563-73. PubMed ID: 11310590
    [Abstract] [Full Text] [Related]

  • 8. Iron chelation studies using desferrioxamine and the potential oral chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, in normal and iron loaded rats.
    Kontoghiorghes GJ, Sheppard L, Hoffbrand AV, Charalambous J, Tikerpae J, Pippard MJ.
    J Clin Pathol; 1987 Apr 01; 40(4):404-8. PubMed ID: 3584483
    [Abstract] [Full Text] [Related]

  • 9. A comparison of the iron-clearing properties of 1,2-dimethyl-3-hydroxypyrid-4-one, 1,2-diethyl-3-hydroxypyrid-4-one, and deferoxamine.
    Bergeron RJ, Streiff RR, Wiegand J, Luchetta G, Creary EA, Peter HH.
    Blood; 1992 Apr 01; 79(7):1882-90. PubMed ID: 1558978
    [Abstract] [Full Text] [Related]

  • 10. The effect of N-alkyl modification on the antimalarial activity of 3-hydroxypyridin-4-one oral iron chelators.
    Hershko C, Theanacho EN, Spira DT, Peter HH, Dobbin P, Hider RC.
    Blood; 1991 Feb 01; 77(3):637-43. PubMed ID: 1991172
    [Abstract] [Full Text] [Related]

  • 11. Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant.
    Porter JB, Gyparaki M, Burke LC, Huehns ER, Sarpong P, Saez V, Hider RC.
    Blood; 1988 Nov 01; 72(5):1497-503. PubMed ID: 3179437
    [Abstract] [Full Text] [Related]

  • 12. Enhancement of iron chelation by desferrioxamine entrapped in red blood cell ghosts.
    Green R, Miller J, Crosby W.
    Blood; 1981 May 01; 57(5):866-72. PubMed ID: 7214016
    [Abstract] [Full Text] [Related]

  • 13. Mechanism of in vivo iron chelation by pyridoxal isonicotinoyl hydrazone and other imino derivatives of pyridoxal.
    Hershko C, Avramovici-Grisaru S, Link G, Gelfand L, Sarel S.
    J Lab Clin Med; 1981 Jul 01; 98(1):99-108. PubMed ID: 7252329
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of iron-chelating agents in an in vivo system: potential usefulness of EHPG, a powerful iron-chelating drug.
    Hershko C, Grady RW, Link G.
    Br J Haematol; 1982 Jun 01; 51(2):251-60. PubMed ID: 7082583
    [Abstract] [Full Text] [Related]

  • 15. Effect of novel 1-alkyl-3-hydroxy-2-methylpyrid-4-one chelators on uptake and release of iron from macrophages.
    Brock JH, Licéaga J, Arthur HM, Kontoghiorghes GJ.
    Am J Hematol; 1990 May 01; 34(1):21-5. PubMed ID: 2327400
    [Abstract] [Full Text] [Related]

  • 16. Ability of the orally effective iron chelators dimethyl- and diethyl-hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells.
    Link G, Pinson A, Hershko C.
    Blood; 1994 May 01; 83(9):2692-7. PubMed ID: 8167347
    [Abstract] [Full Text] [Related]

  • 17. Modulation by iron loading and chelation of the uptake of non-transferrin-bound iron by human liver cells.
    Parkes JG, Randell EW, Olivieri NF, Templeton DM.
    Biochim Biophys Acta; 1995 Apr 13; 1243(3):373-80. PubMed ID: 7727512
    [Abstract] [Full Text] [Related]

  • 18. Contrasting interspecies efficacy and toxicology of 1,2-diethyl-3-hydroxypyridin-4-one, CP94, relates to differing metabolism of the iron chelating site.
    Porter JB, Abeysinghe RD, Hoyes KP, Barra C, Huehns ER, Brooks PN, Blackwell MP, Araneta M, Brittenham G, Singh S.
    Br J Haematol; 1993 Sep 13; 85(1):159-68. PubMed ID: 8251385
    [Abstract] [Full Text] [Related]

  • 19. Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice.
    Eybl V, Caisová D, Koutenský J, Kontoghiorghes GJ.
    Arch Toxicol Suppl; 1991 Sep 13; 14():185-7. PubMed ID: 1805729
    [No Abstract] [Full Text] [Related]

  • 20. Development and evaluation of the improved iron chelating agents EHPG, HBED and their dimethyl esters.
    Hershko C, Grady RW, Link G.
    Haematologia (Budap); 1984 Sep 13; 17(1):25-33. PubMed ID: 6427069
    [Abstract] [Full Text] [Related]


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