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605 related items for PubMed ID: 17284614

  • 1. Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction.
    Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H.
    Proc Natl Acad Sci U S A; 2007 Feb 13; 104(7):2349-54. PubMed ID: 17284614
    [Abstract] [Full Text] [Related]

  • 2. Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice.
    Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H.
    Dev Cell; 2005 Jun 13; 8(6):907-14. PubMed ID: 15935779
    [Abstract] [Full Text] [Related]

  • 3. Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL.
    Nishino T, Miyaji K, Ishiwata N, Arai K, Yui M, Asai Y, Nakauchi H, Iwama A.
    Exp Hematol; 2009 Nov 13; 37(11):1364-1377.e4. PubMed ID: 19744539
    [Abstract] [Full Text] [Related]

  • 4. Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals.
    Takizawa H, Eto K, Yoshikawa A, Nakauchi H, Takatsu K, Takaki S.
    Exp Hematol; 2008 Jul 13; 36(7):897-906. PubMed ID: 18456388
    [Abstract] [Full Text] [Related]

  • 5. Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2.
    Bersenev A, Wu C, Balcerek J, Tong W.
    J Clin Invest; 2008 Aug 13; 118(8):2832-44. PubMed ID: 18618018
    [Abstract] [Full Text] [Related]

  • 6. A novel function of interleukin-10 promoting self-renewal of hematopoietic stem cells.
    Kang YJ, Yang SJ, Park G, Cho B, Min CK, Kim TY, Lee JS, Oh IH.
    Stem Cells; 2007 Jul 13; 25(7):1814-22. PubMed ID: 17464085
    [Abstract] [Full Text] [Related]

  • 7. Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.
    Buza-Vidas N, Antonchuk J, Qian H, Månsson R, Luc S, Zandi S, Anderson K, Takaki S, Nygren JM, Jensen CT, Jacobsen SE.
    Genes Dev; 2006 Aug 01; 20(15):2018-23. PubMed ID: 16882979
    [Abstract] [Full Text] [Related]

  • 8. Insights into signaling and function of hematopoietic stem cells at the single-cell level.
    Yamazaki S, Nakauchi H.
    Curr Opin Hematol; 2009 Jul 01; 16(4):255-8. PubMed ID: 19465850
    [Abstract] [Full Text] [Related]

  • 9. Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function.
    Norddahl GL, Wahlestedt M, Gisler S, Sigvardsson M, Bryder D.
    Aging Cell; 2012 Dec 01; 11(6):1128-31. PubMed ID: 22809070
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of Lnk in mouse induced pluripotent stem cells promotes hematopoietic cell generation.
    Tashiro K, Omori M, Kawabata K, Hirata N, Yamaguchi T, Sakurai F, Takaki S, Mizuguchi H.
    Stem Cells Dev; 2012 Dec 10; 21(18):3381-90. PubMed ID: 22738147
    [Abstract] [Full Text] [Related]

  • 11. Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis.
    Kato Y, Iwama A, Tadokoro Y, Shimoda K, Minoguchi M, Akira S, Tanaka M, Miyajima A, Kitamura T, Nakauchi H.
    J Exp Med; 2005 Jul 04; 202(1):169-79. PubMed ID: 15998795
    [Abstract] [Full Text] [Related]

  • 12. Hematopoietic stem cell self-renewal.
    Akala OO, Clarke MF.
    Curr Opin Genet Dev; 2006 Oct 04; 16(5):496-501. PubMed ID: 16919448
    [Abstract] [Full Text] [Related]

  • 13. HOXB4-induced self-renewal of hematopoietic stem cells is significantly enhanced by p21 deficiency.
    Miyake N, Brun AC, Magnusson M, Miyake K, Scadden DT, Karlsson S.
    Stem Cells; 2006 Mar 04; 24(3):653-61. PubMed ID: 16210402
    [Abstract] [Full Text] [Related]

  • 14. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
    Tong W, Lodish HF.
    J Exp Med; 2004 Sep 06; 200(5):569-80. PubMed ID: 15337790
    [Abstract] [Full Text] [Related]

  • 15. Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche.
    Kim JA, Kang YJ, Park G, Kim M, Park YO, Kim H, Leem SH, Chu IS, Lee JS, Jho EH, Oh IH.
    Stem Cells; 2009 Jun 06; 27(6):1318-29. PubMed ID: 19489023
    [Abstract] [Full Text] [Related]

  • 16. Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL.
    Suzuki N, Yamazaki S, Ema H, Yamaguchi T, Nakauchi H, Takaki S.
    Exp Hematol; 2012 Feb 06; 40(2):166-74.e3. PubMed ID: 22101255
    [Abstract] [Full Text] [Related]

  • 17. Involvement of protein kinase C-epsilon in signal transduction of thrombopoietin in enhancement of interleukin-3-dependent proliferation of primitive hematopoietic progenitors.
    Shiroshita N, Musashi M, Sakurada K, Kimura K, Tsuda Y, Ota S, Iwasaki H, Miyazaki T, Kato T, Miyazaki H, Shimosaka A, Asaka M.
    J Pharmacol Exp Ther; 2001 Jun 06; 297(3):868-75. PubMed ID: 11356906
    [Abstract] [Full Text] [Related]

  • 18. Common and distinct features of cytokine effects on hematopoietic stem and progenitor cells revealed by dose-response surface analysis.
    Audet J, Miller CL, Eaves CJ, Piret JM.
    Biotechnol Bioeng; 2002 Nov 20; 80(4):393-404. PubMed ID: 12325147
    [Abstract] [Full Text] [Related]

  • 19. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.
    Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T.
    Nat Immunol; 2005 Mar 20; 6(3):314-22. PubMed ID: 15665828
    [Abstract] [Full Text] [Related]

  • 20. Pivotal role of lnk adaptor protein in endothelial progenitor cell biology for vascular regeneration.
    Kwon SM, Suzuki T, Kawamoto A, Ii M, Eguchi M, Akimaru H, Wada M, Matsumoto T, Masuda H, Nakagawa Y, Nishimura H, Kawai K, Takaki S, Asahara T.
    Circ Res; 2009 Apr 24; 104(8):969-77. PubMed ID: 19325148
    [Abstract] [Full Text] [Related]

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