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Journal Abstract Search

262 related items for PubMed ID: 17287401

  • 1. Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.
    Lane JR, Powney B, Wise A, Rees S, Milligan G.
    Mol Pharmacol; 2007 May; 71(5):1349-59. PubMed ID: 17287401
    [Abstract] [Full Text] [Related]

  • 2. Missing links: mechanisms of protean agonism.
    Neubig RR.
    Mol Pharmacol; 2007 May; 71(5):1200-2. PubMed ID: 17293557
    [Abstract] [Full Text] [Related]

  • 3. Functional coupling of the human dopamine D2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity.
    Gazi L, Nickolls SA, Strange PG.
    Br J Pharmacol; 2003 Mar; 138(5):775-86. PubMed ID: 12642378
    [Abstract] [Full Text] [Related]

  • 4. Measurement of agonist-dependent and -independent signal initiation of alpha(1b)-adrenoceptor mutants by direct analysis of guanine nucleotide exchange on the G protein galpha(11).
    Carrillo JJ, Stevens PA, Milligan G.
    J Pharmacol Exp Ther; 2002 Sep; 302(3):1080-8. PubMed ID: 12183666
    [Abstract] [Full Text] [Related]

  • 5. G protein coupling and ligand selectivity of the D2L and D3 dopamine receptors.
    Lane JR, Powney B, Wise A, Rees S, Milligan G.
    J Pharmacol Exp Ther; 2008 Apr; 325(1):319-30. PubMed ID: 18218829
    [Abstract] [Full Text] [Related]

  • 6. No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers.
    Schnell D, Burleigh K, Trick J, Seifert R.
    J Pharmacol Exp Ther; 2010 Mar; 332(3):996-1005. PubMed ID: 19959746
    [Abstract] [Full Text] [Related]

  • 7. S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: I. Cellular, electrophysiological, and neurochemical profile in comparison with ropinirole.
    Millan MJ, Cussac D, Gobert A, Lejeune F, Rivet JM, Mannoury La Cour C, Newman-Tancredi A, Peglion JL.
    J Pharmacol Exp Ther; 2004 Jun; 309(3):903-20. PubMed ID: 14978194
    [Abstract] [Full Text] [Related]

  • 8. Comparative analysis of the efficacy of A1 adenosine receptor activation of Gi/o alpha G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-Gi/o alpha fusion proteins.
    Wise A, Sheehan M, Rees S, Lee M, Milligan G.
    Biochemistry; 1999 Feb 23; 38(8):2272-8. PubMed ID: 10029519
    [Abstract] [Full Text] [Related]

  • 9. Effects of partial agonists and Mg2+ ions on the interaction of M2 muscarinic acetylcholine receptor and G protein Galpha i1 subunit in the M2-Galpha i1 fusion protein.
    Zhang Q, Okamura M, Guo ZD, Niwa S, Haga T.
    J Biochem; 2004 May 23; 135(5):589-96. PubMed ID: 15173197
    [Abstract] [Full Text] [Related]

  • 10. In vivo reconstitution of dopamine D2S receptor-mediated G protein activation in baculovirus-infected insect cells: preferred coupling to Gi1 versus Gi2.
    Grünewald S, Reiländer H, Michel H.
    Biochemistry; 1996 Dec 03; 35(48):15162-73. PubMed ID: 8952463
    [Abstract] [Full Text] [Related]

  • 11. Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.
    Stanasila L, Lim WK, Neubig RR, Pattus F.
    J Neurochem; 2000 Sep 03; 75(3):1190-9. PubMed ID: 10936202
    [Abstract] [Full Text] [Related]

  • 12. h5-HT(1B) receptor-mediated constitutive Galphai3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT.
    Newman-Tancredi A, Cussac D, Marini L, Touzard M, Millan MJ.
    Br J Pharmacol; 2003 Mar 03; 138(6):1077-84. PubMed ID: 12684263
    [Abstract] [Full Text] [Related]

  • 13. Comparison of the relative efficacy and potency of mu-opioid agonists to activate Galpha(i/o) proteins containing a pertussis toxin-insensitive mutation.
    Clark MJ, Furman CA, Gilson TD, Traynor JR.
    J Pharmacol Exp Ther; 2006 May 03; 317(2):858-64. PubMed ID: 16436499
    [Abstract] [Full Text] [Related]

  • 14. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.
    Heinrich JN, Brennan J, Lai MH, Sullivan K, Hornby G, Popiolek M, Jiang LX, Pausch MH, Stack G, Marquis KL, Andree TH.
    Eur J Pharmacol; 2006 Dec 15; 552(1-3):36-45. PubMed ID: 17056032
    [Abstract] [Full Text] [Related]

  • 15. Development of generic calcium imaging assay for monitoring Gi-coupled receptors and G-protein interaction.
    Ueda T, Ugawa S, Ishida Y, Hondoh A, Shimada S.
    J Biomol Screen; 2009 Aug 15; 14(7):781-8. PubMed ID: 19541673
    [Abstract] [Full Text] [Related]

  • 16. Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells.
    Zhang L, Tetrault J, Wang W, Loh HH, Law PY.
    Mol Pharmacol; 2006 Jun 15; 69(6):1810-9. PubMed ID: 16525132
    [Abstract] [Full Text] [Related]

  • 17. Dopamine D2 receptor-mediated G protein activation assessed by agonist-stimulated [35S]guanosine 5'-O-(gamma-thiotriphosphate) binding in rat striatal membranes.
    Odagaki Y, Toyoshima R.
    Prog Neuropsychopharmacol Biol Psychiatry; 2006 Sep 30; 30(7):1304-12. PubMed ID: 16824659
    [Abstract] [Full Text] [Related]

  • 18. The influence of G protein subtype on agonist action at D2 dopamine receptors.
    Nickolls SA, Strange PG.
    Neuropharmacology; 2004 Nov 30; 47(6):860-72. PubMed ID: 15527820
    [Abstract] [Full Text] [Related]

  • 19. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist.
    Glennon JC, Van Scharrenburg G, Ronken E, Hesselink MB, Reinders JH, Van Der Neut M, Long SK, Feenstra RW, McCreary AC.
    Synapse; 2006 Dec 15; 60(8):599-608. PubMed ID: 17001660
    [Abstract] [Full Text] [Related]

  • 20. D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides.
    Webb CK, McCudden CR, Willard FS, Kimple RJ, Siderovski DP, Oxford GS.
    J Neurochem; 2005 Mar 15; 92(6):1408-18. PubMed ID: 15748159
    [Abstract] [Full Text] [Related]

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