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Journal Abstract Search


201 related items for PubMed ID: 17291753

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  • 3. N-Phenyl-N'-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2: role of omega-hydroxyl group in the covalent binding to beta-tubulin.
    Fortin S, Moreau E, Patenaude A, Desjardins M, Lacroix J, Rousseau JL, C-Gaudreault R.
    Bioorg Med Chem; 2007 Feb 01; 15(3):1430-8. PubMed ID: 17118664
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  • 4. Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin.
    Fortin S, Wei L, Moreau E, Labrie P, Petitclerc E, Kotra LP, C-Gaudreault R.
    Bioorg Med Chem; 2009 May 15; 17(10):3690-7. PubMed ID: 19398206
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  • 7. A comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N'-(2-chloroethyl)ureas targeting the colchicine-binding site as anticancer agents.
    Fortin S, Labrie P, Moreau E, Wei L, Kotra LP, C-Gaudreault R.
    Bioorg Med Chem; 2008 Feb 15; 16(4):1914-26. PubMed ID: 18023585
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  • 8. Styryl-N-phenyl-N'-(2-chloroethyl)ureas and styrylphenylimidazolidin-2-ones as new potent microtubule-disrupting agents using combretastatin A-4 as model.
    Gagné-Boulet M, Fortin S, Lacroix J, Lefebvre CA, Côté MF, C-Gaudreault R.
    Eur J Med Chem; 2015 Jul 15; 100():34-43. PubMed ID: 26069928
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  • 9. Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives.
    Kaffy J, Pontikis R, Florent JC, Monneret C.
    Org Biomol Chem; 2005 Jul 21; 3(14):2657-60. PubMed ID: 15999202
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  • 10. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues.
    Theeramunkong S, Caldarelli A, Massarotti A, Aprile S, Caprioglio D, Zaninetti R, Teruggi A, Pirali T, Grosa G, Tron GC, Genazzani AA.
    J Med Chem; 2011 Jul 28; 54(14):4977-86. PubMed ID: 21696175
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  • 11. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K, Hentzen J, dit Chabert JF, Ducki S, Gani OA, Sylte I, Skrede M, Flørenes VA, Hansen TV.
    Bioorg Med Chem; 2008 May 01; 16(9):4829-38. PubMed ID: 18396050
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  • 12. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
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  • 13. Novel potent antimitotic heterocyclic ketones: synthesis, antiproliferative activity, and structure-activity relationships.
    Hu L, Jiang JD, Qu J, Li Y, Jin J, Li ZR, Boykin DW.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3613-7. PubMed ID: 17482458
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  • 14. Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety.
    Maya AB, Pérez-Melero C, Mateo C, Alonso D, Fernández JL, Gajate C, Mollinedo F, Peláez R, Caballero E, Medarde M.
    J Med Chem; 2005 Jan 27; 48(2):556-68. PubMed ID: 15658869
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  • 15. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
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  • 16. Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles.
    Duan JX, Cai X, Meng F, Lan L, Hart C, Matteucci M.
    J Med Chem; 2007 Mar 08; 50(5):1001-6. PubMed ID: 17286393
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  • 17. Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
    Carr M, Greene LM, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ.
    Eur J Med Chem; 2010 Dec 08; 45(12):5752-66. PubMed ID: 20933304
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  • 18. Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N'-(2-chloroethyl)ureas.
    Fortin S, Moreau E, Lacroix J, Côté MF, Petitclerc E, C-Gaudreault R.
    Eur J Med Chem; 2010 Jul 08; 45(7):2928-37. PubMed ID: 20400211
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  • 19. Synthesis and biological evaluation of C-12' substituted vinflunine derivatives.
    Lei XS, Yu XD, Yin L, Liu ZH, Tang PC.
    Bioorg Med Chem Lett; 2008 Aug 15; 18(16):4602-5. PubMed ID: 18653334
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  • 20. Synthesis, modelling, and antimitotic properties of tricyclic systems characterised by a 2-(5-Phenyl-1H-pyrrol-3-yl)-1,3,4-oxadiazole moiety.
    Pinna GA, Murineddu G, Murruzzu C, Zuco V, Zunino F, Cappelletti G, Artali R, Cignarella G, Solano L, Villa S.
    ChemMedChem; 2009 Jun 15; 4(6):998-1009. PubMed ID: 19291736
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