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Journal Abstract Search

172 related items for PubMed ID: 17292610

  • 21. Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties.
    Flesch D, Gabler M, Lill A, Gomez RC, Steri R, Schneider G, Stark H, Schubert-Zsilavecz M, Merk D.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3490-8. PubMed ID: 25934227
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  • 22. FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.
    Zhang Q, He F, Kuruba R, Gao X, Wilson A, Li J, Billiar TR, Pitt BR, Xie W, Li S.
    Cardiovasc Res; 2008 Feb 01; 77(3):560-9. PubMed ID: 18006431
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  • 25. FXR-mediated regulation of eNOS expression in vascular endothelial cells.
    Li J, Wilson A, Kuruba R, Zhang Q, Gao X, He F, Zhang LM, Pitt BR, Xie W, Li S.
    Cardiovasc Res; 2008 Jan 01; 77(1):169-77. PubMed ID: 18006476
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  • 29. Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.
    Feng S, Yang M, Zhang Z, Wang Z, Hong D, Richter H, Benson GM, Bleicher K, Grether U, Martin RE, Plancher JM, Kuhn B, Rudolph MG, Chen L.
    Bioorg Med Chem Lett; 2009 May 01; 19(9):2595-8. PubMed ID: 19328688
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  • 30. Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor.
    Sepe V, Bifulco G, Renga B, D'Amore C, Fiorucci S, Zampella A.
    J Med Chem; 2011 Mar 10; 54(5):1314-20. PubMed ID: 21309576
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  • 33. Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR).
    Flatt B, Martin R, Wang TL, Mahaney P, Murphy B, Gu XH, Foster P, Li J, Pircher P, Petrowski M, Schulman I, Westin S, Wrobel J, Yan G, Bischoff E, Daige C, Mohan R.
    J Med Chem; 2009 Feb 26; 52(4):904-7. PubMed ID: 19159286
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  • 34. Is antagonism of E/Z-guggulsterone at the farnesoid X receptor mediated by a noncanonical binding site? A molecular modeling study.
    Meyer U, Costantino G, Macchiarulo A, Pellicciari R.
    J Med Chem; 2005 Nov 03; 48(22):6948-55. PubMed ID: 16250653
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  • 35. Pyrrole[2,3-d]azepino compounds as agonists of the farnesoid X receptor (FXR).
    Mehlmann JF, Crawley ML, Lundquist JT, Unwalla RJ, Harnish DC, Evans MJ, Kim CY, Wrobel JE, Mahaney PE.
    Bioorg Med Chem Lett; 2009 Sep 15; 19(18):5289-92. PubMed ID: 19683924
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  • 36. Discovery of new non-steroidal farnesoid X receptor modulators through 3D shape similarity search and structure-based virtual screening.
    Wang L, Si P, Sheng Y, Chen Y, Wan P, Shen X, Tang Y, Chen L, Li W.
    Chem Biol Drug Des; 2015 Apr 15; 85(4):481-7. PubMed ID: 25228339
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  • 38. Farnesoid X receptor agonists in biliary tract disease.
    Fiorucci S, Baldelli F.
    Curr Opin Gastroenterol; 2009 May 15; 25(3):252-9. PubMed ID: 19300246
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