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Journal Abstract Search


349 related items for PubMed ID: 17302523

  • 1. FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis.
    Baumruker T, Billich A, Brinkmann V.
    Expert Opin Investig Drugs; 2007 Mar; 16(3):283-9. PubMed ID: 17302523
    [Abstract] [Full Text] [Related]

  • 2. FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system.
    Brinkmann V.
    Br J Pharmacol; 2009 Nov; 158(5):1173-82. PubMed ID: 19814729
    [Abstract] [Full Text] [Related]

  • 3. [New therapeutic approach for autoimmune diseases by the sphingosine 1-phosphate receptor modulator, fingolimod (FTY720)].
    Chiba K.
    Yakugaku Zasshi; 2009 Jun; 129(6):655-65. PubMed ID: 19483408
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis.
    Chun J, Hartung HP.
    Clin Neuropharmacol; 2010 Jun; 33(2):91-101. PubMed ID: 20061941
    [Abstract] [Full Text] [Related]

  • 5. Discovery of fingolimod, the sphingosine 1-phosphate receptor modulator and its application for the therapy of multiple sclerosis.
    Chiba K, Adachi K.
    Future Med Chem; 2012 Apr; 4(6):771-81. PubMed ID: 22530640
    [Abstract] [Full Text] [Related]

  • 6. Clinical immunology of the sphingosine 1-phosphate receptor modulator fingolimod (FTY720) in multiple sclerosis.
    Mehling M, Johnson TA, Antel J, Kappos L, Bar-Or A.
    Neurology; 2011 Feb 22; 76(8 Suppl 3):S20-7. PubMed ID: 21339487
    [Abstract] [Full Text] [Related]

  • 7. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation.
    Choi JW, Gardell SE, Herr DR, Rivera R, Lee CW, Noguchi K, Teo ST, Yung YC, Lu M, Kennedy G, Chun J.
    Proc Natl Acad Sci U S A; 2011 Jan 11; 108(2):751-6. PubMed ID: 21177428
    [Abstract] [Full Text] [Related]

  • 8. Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720.
    Hiestand PC, Rausch M, Meier DP, Foster CA.
    Prog Drug Res; 2008 Jan 11; 66():361, 363-81. PubMed ID: 18416311
    [Abstract] [Full Text] [Related]

  • 9. The neurobiology of sphingosine 1-phosphate signaling and sphingosine 1-phosphate receptor modulators.
    Soliven B, Miron V, Chun J.
    Neurology; 2011 Feb 22; 76(8 Suppl 3):S9-14. PubMed ID: 21339490
    [Abstract] [Full Text] [Related]

  • 10. [A new therapeutic approach for autoimmune diseases by the sphingosine 1-phosphate receptor modulator, fingolimod (FTY720)].
    Chiba K.
    Nihon Rinsho Meneki Gakkai Kaishi; 2009 Apr 22; 32(2):92-101. PubMed ID: 19404007
    [Abstract] [Full Text] [Related]

  • 11. FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors.
    Chiba K.
    Pharmacol Ther; 2005 Dec 22; 108(3):308-19. PubMed ID: 15951022
    [Abstract] [Full Text] [Related]

  • 12. Neurological S1P signaling as an emerging mechanism of action of oral FTY720 (fingolimod) in multiple sclerosis.
    Lee CW, Choi JW, Chun J.
    Arch Pharm Res; 2010 Oct 22; 33(10):1567-74. PubMed ID: 21052934
    [Abstract] [Full Text] [Related]

  • 13. FTY720 on the way from the base camp to the summit of the mountain: relevance for remyelination.
    Kipp M, Amor S.
    Mult Scler; 2012 Mar 22; 18(3):258-63. PubMed ID: 22383435
    [Abstract] [Full Text] [Related]

  • 14. Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation.
    Hla T, Brinkmann V.
    Neurology; 2011 Feb 22; 76(8 Suppl 3):S3-8. PubMed ID: 21339489
    [Abstract] [Full Text] [Related]

  • 15. Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.
    Natarajan V, Dudek SM, Jacobson JR, Moreno-Vinasco L, Huang LS, Abassi T, Mathew B, Zhao Y, Wang L, Bittman R, Weichselbaum R, Berdyshev E, Garcia JG.
    Am J Respir Cell Mol Biol; 2013 Jul 22; 49(1):6-17. PubMed ID: 23449739
    [Abstract] [Full Text] [Related]

  • 16. Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy.
    Groves A, Kihara Y, Chun J.
    J Neurol Sci; 2013 May 15; 328(1-2):9-18. PubMed ID: 23518370
    [Abstract] [Full Text] [Related]

  • 17. [Fingolimod therapy in multiple sclerosis--the issue of the pathomechanism].
    Tar L, Vécsei L.
    Ideggyogy Sz; 2012 Mar 30; 65(3-4):83-100. PubMed ID: 23136726
    [Abstract] [Full Text] [Related]

  • 18. Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology.
    Brinkmann V.
    Pharmacol Ther; 2007 Jul 30; 115(1):84-105. PubMed ID: 17561264
    [Abstract] [Full Text] [Related]

  • 19. FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function.
    Brinkmann V, Cyster JG, Hla T.
    Am J Transplant; 2004 Jul 30; 4(7):1019-25. PubMed ID: 15196057
    [Abstract] [Full Text] [Related]

  • 20. Molecular targets of FTY720 (fingolimod).
    Pitman MR, Woodcock JM, Lopez AF, Pitson SM.
    Curr Mol Med; 2012 Dec 30; 12(10):1207-19. PubMed ID: 22834825
    [Abstract] [Full Text] [Related]


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