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Journal Abstract Search

719 related items for PubMed ID: 17308038

  • 1. The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents.
    Boess FG, De Vry J, Erb C, Flessner T, Hendrix M, Luithle J, Methfessel C, Riedl B, Schnizler K, van der Staay FJ, van Kampen M, Wiese WB, Koenig G.
    J Pharmacol Exp Ther; 2007 May; 321(2):716-25. PubMed ID: 17308038
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological and behavioral profile of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-6-chinolincarboxamide (EVP-5141), a novel α7 nicotinic acetylcholine receptor agonist/serotonin 5-HT3 receptor antagonist.
    Boess FG, de Vry J, Erb C, Flessner T, Hendrix M, Luithle J, Methfessel C, Schnizler K, van der Staay FJ, van Kampen M, Wiese WB, König G.
    Psychopharmacology (Berl); 2013 May; 227(1):1-17. PubMed ID: 23241647
    [Abstract] [Full Text] [Related]

  • 3. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.
    Wishka DG, Walker DP, Yates KM, Reitz SC, Jia S, Myers JK, Olson KL, Jacobsen EJ, Wolfe ML, Groppi VE, Hanchar AJ, Thornburgh BA, Cortes-Burgos LA, Wong EH, Staton BA, Raub TJ, Higdon NR, Wall TM, Hurst RS, Walters RR, Hoffmann WE, Hajos M, Franklin S, Carey G, Gold LH, Cook KK, Sands SB, Zhao SX, Soglia JR, Kalgutkar AS, Arneric SP, Rogers BN.
    J Med Chem; 2006 Jul 13; 49(14):4425-36. PubMed ID: 16821801
    [Abstract] [Full Text] [Related]

  • 4. In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.
    Malysz J, Anderson DJ, Grønlien JH, Ji J, Bunnelle WH, Håkerud M, Thorin-Hagene K, Ween H, Helfrich R, Hu M, Gubbins E, Gopalakrishnan S, Puttfarcken PS, Briggs CA, Li J, Meyer MD, Dyhring T, Ahring PK, Nielsen EØ, Peters D, Timmermann DB, Gopalakrishnan M.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):863-74. PubMed ID: 20504915
    [Abstract] [Full Text] [Related]

  • 5. EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.
    Prickaerts J, van Goethem NP, Chesworth R, Shapiro G, Boess FG, Methfessel C, Reneerkens OA, Flood DG, Hilt D, Gawryl M, Bertrand S, Bertrand D, König G.
    Neuropharmacology; 2012 Feb 01; 62(2):1099-110. PubMed ID: 22085888
    [Abstract] [Full Text] [Related]

  • 6. Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25-35-mediated cognitive deficits in mice.
    Sadigh-Eteghad S, Talebi M, Mahmoudi J, Babri S, Shanehbandi D.
    Neuroscience; 2015 Jul 09; 298():81-93. PubMed ID: 25881725
    [Abstract] [Full Text] [Related]

  • 7. Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity.
    Acker BA, Jacobsen EJ, Rogers BN, Wishka DG, Reitz SC, Piotrowski DW, Myers JK, Wolfe ML, Groppi VE, Thornburgh BA, Tinholt PM, Walters RR, Olson BA, Fitzgerald L, Staton BA, Raub TJ, Krause M, Li KS, Hoffmann WE, Hajos M, Hurst RS, Walker DP.
    Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3611-5. PubMed ID: 18490160
    [Abstract] [Full Text] [Related]

  • 8. In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease.
    Bitner RS, Bunnelle WH, Decker MW, Drescher KU, Kohlhaas KL, Markosyan S, Marsh KC, Nikkel AL, Browman K, Radek R, Anderson DJ, Buccafusco J, Gopalakrishnan M.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):875-86. PubMed ID: 20504913
    [Abstract] [Full Text] [Related]

  • 9. JN403, in vitro characterization of a novel nicotinic acetylcholine receptor alpha7 selective agonist.
    Feuerbach D, Nozulak J, Lingenhoehl K, McAllister K, Hoyer D.
    Neurosci Lett; 2007 Apr 06; 416(1):61-5. PubMed ID: 17314009
    [Abstract] [Full Text] [Related]

  • 10. Brainstem cholinergic pathways diminish cardiovascular and neuroinflammatory actions of endotoxemia in rats: Role of NFκB/α7/α4β2AChRs signaling.
    Sallam MY, El-Gowilly SM, Fouda MA, Abd-Alhaseeb MM, El-Mas MM.
    Neuropharmacology; 2019 Oct 06; 157():107683. PubMed ID: 31247270
    [Abstract] [Full Text] [Related]

  • 11. TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia.
    Hauser TA, Kucinski A, Jordan KG, Gatto GJ, Wersinger SR, Hesse RA, Stachowiak EK, Stachowiak MK, Papke RL, Lippiello PM, Bencherif M.
    Biochem Pharmacol; 2009 Oct 01; 78(7):803-12. PubMed ID: 19482012
    [Abstract] [Full Text] [Related]

  • 12. Identification and in vitro pharmacological characterization of a novel and selective α7 nicotinic acetylcholine receptor agonist, Br-IQ17B.
    Tang JS, Xie BX, Bian XL, Xue Y, Wei NN, Zhou JH, Hao YC, Li G, Zhang LR, Wang KW.
    Acta Pharmacol Sin; 2015 Jul 01; 36(7):800-12. PubMed ID: 25948478
    [Abstract] [Full Text] [Related]

  • 13. The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats.
    Hajós M, Hurst RS, Hoffmann WE, Krause M, Wall TM, Higdon NR, Groppi VE.
    J Pharmacol Exp Ther; 2005 Mar 01; 312(3):1213-22. PubMed ID: 15523001
    [Abstract] [Full Text] [Related]

  • 14. Methyllycaconitine: a non-radiolabeled ligand for mapping α7 neuronal nicotinic acetylcholine receptors - in vivo target localization and biodistribution in rat brain.
    Nirogi R, Kandikere V, Bhyrapuneni G, Saralaya R, Muddana N, Komarneni P.
    J Pharmacol Toxicol Methods; 2012 Jul 01; 66(1):22-8. PubMed ID: 22609758
    [Abstract] [Full Text] [Related]

  • 15. RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents.
    Wallace TL, Callahan PM, Tehim A, Bertrand D, Tombaugh G, Wang S, Xie W, Rowe WB, Ong V, Graham E, Terry AV, Rodefer JS, Herbert B, Murray M, Porter R, Santarelli L, Lowe DA.
    J Pharmacol Exp Ther; 2011 Jan 01; 336(1):242-53. PubMed ID: 20959364
    [Abstract] [Full Text] [Related]

  • 16. Cognitive improvements in a mouse model with substituted 1,2,3-triazole agonists for nicotinic acetylcholine receptors.
    Arunrungvichian K, Boonyarat C, Fokin VV, Taylor P, Vajragupta O.
    ACS Chem Neurosci; 2015 Aug 19; 6(8):1331-40. PubMed ID: 25978789
    [Abstract] [Full Text] [Related]

  • 17. AR-R 17779 improves social recognition in rats by activation of nicotinic alpha7 receptors.
    Van Kampen M, Selbach K, Schneider R, Schiegel E, Boess F, Schreiber R.
    Psychopharmacology (Berl); 2004 Apr 19; 172(4):375-83. PubMed ID: 14727003
    [Abstract] [Full Text] [Related]

  • 18. Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders.
    Roncarati R, Scali C, Comery TA, Grauer SM, Aschmi S, Bothmann H, Jow B, Kowal D, Gianfriddo M, Kelley C, Zanelli U, Ghiron C, Haydar S, Dunlop J, Terstappen GC.
    J Pharmacol Exp Ther; 2009 May 19; 329(2):459-68. PubMed ID: 19223665
    [Abstract] [Full Text] [Related]

  • 19. Effects of the novel α7 nicotinic acetylcholine receptor agonist ABT-107 on sensory gating in DBA/2 mice: pharmacodynamic characterization.
    Radek RJ, Robb HM, Stevens KE, Gopalakrishnan M, Bitner RS.
    J Pharmacol Exp Ther; 2012 Dec 19; 343(3):736-45. PubMed ID: 22988063
    [Abstract] [Full Text] [Related]

  • 20. Importance of M2-M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera.
    Grønlien JH, Ween H, Thorin-Hagene K, Cassar S, Li J, Briggs CA, Gopalakrishnan M, Malysz J.
    Eur J Pharmacol; 2010 Nov 25; 647(1-3):37-47. PubMed ID: 20816816
    [Abstract] [Full Text] [Related]

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