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492 related items for PubMed ID: 17308097

  • 1. A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo.
    Jallal H, Valentino ML, Chen G, Boschelli F, Ali S, Rabbani SA.
    Cancer Res; 2007 Feb 15; 67(4):1580-8. PubMed ID: 17308097
    [Abstract] [Full Text] [Related]

  • 2. SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling.
    Coluccia AM, Benati D, Dekhil H, De Filippo A, Lan C, Gambacorti-Passerini C.
    Cancer Res; 2006 Feb 15; 66(4):2279-86. PubMed ID: 16489032
    [Abstract] [Full Text] [Related]

  • 3. SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice.
    Golas JM, Arndt K, Etienne C, Lucas J, Nardin D, Gibbons J, Frost P, Ye F, Boschelli DH, Boschelli F.
    Cancer Res; 2003 Jan 15; 63(2):375-81. PubMed ID: 12543790
    [Abstract] [Full Text] [Related]

  • 4. SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models.
    Golas JM, Lucas J, Etienne C, Golas J, Discafani C, Sridharan L, Boghaert E, Arndt K, Ye F, Boschelli DH, Li F, Titsch C, Huselton C, Chaudhary I, Boschelli F.
    Cancer Res; 2005 Jun 15; 65(12):5358-64. PubMed ID: 15958584
    [Abstract] [Full Text] [Related]

  • 5. PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.
    Ma JG, Huang H, Chen SM, Chen Y, Xin XL, Lin LP, Ding J, Liu H, Meng LH.
    Breast Cancer Res Treat; 2011 Nov 15; 130(1):85-96. PubMed ID: 21181437
    [Abstract] [Full Text] [Related]

  • 6. Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors.
    Tan M, Li P, Sun M, Yin G, Yu D.
    Oncogene; 2006 Jun 01; 25(23):3286-95. PubMed ID: 16407820
    [Abstract] [Full Text] [Related]

  • 7. Role of non-receptor and receptor tyrosine kinases (TKs) in the antitumor action of alpha-difluoromethylornithine (DFMO) in breast cancer cells.
    Xu H, Washington S, Verderame MF, Manni A.
    Breast Cancer Res Treat; 2008 Nov 01; 112(2):255-61. PubMed ID: 18097746
    [Abstract] [Full Text] [Related]

  • 8. Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways.
    Chen PH, Peng CY, Pai HC, Teng CM, Chen CC, Yang CR.
    J Nutr Biochem; 2011 Aug 01; 22(8):732-40. PubMed ID: 21062671
    [Abstract] [Full Text] [Related]

  • 9. Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells.
    Lee WJ, Chen WK, Wang CJ, Lin WL, Tseng TH.
    Toxicol Appl Pharmacol; 2008 Jan 15; 226(2):178-91. PubMed ID: 17961621
    [Abstract] [Full Text] [Related]

  • 10. Persistent Cdk2 inactivation drives growth arrest of BCR-ABL-expressing cells in response to dual inhibitor of SRC and ABL kinases SKI606.
    Mancini M, Brusa G, Zuffa E, Corrado P, Martinelli G, Grafone T, Barbieri E, Santucci MA.
    Leuk Res; 2007 Jul 15; 31(7):979-87. PubMed ID: 17129604
    [Abstract] [Full Text] [Related]

  • 11. Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.
    Moore LD, Isayeva T, Siegal GP, Ponnazhagan S.
    Clin Cancer Res; 2008 Aug 01; 14(15):4961-70. PubMed ID: 18676771
    [Abstract] [Full Text] [Related]

  • 12. TrkA overexpression enhances growth and metastasis of breast cancer cells.
    Lagadec C, Meignan S, Adriaenssens E, Foveau B, Vanhecke E, Romon R, Toillon RA, Oxombre B, Hondermarck H, Le Bourhis X.
    Oncogene; 2009 May 07; 28(18):1960-70. PubMed ID: 19330021
    [Abstract] [Full Text] [Related]

  • 13. Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.
    Azuma H, Ehata S, Miyazaki H, Watabe T, Maruyama O, Imamura T, Sakamoto T, Kiyama S, Kiyama Y, Ubai T, Inamoto T, Takahara S, Itoh Y, Otsuki Y, Katsuoka Y, Miyazono K, Horie S.
    J Natl Cancer Inst; 2005 Dec 07; 97(23):1734-46. PubMed ID: 16333029
    [Abstract] [Full Text] [Related]

  • 14. Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors).
    Hirokawa Y, Levitzki A, Lessene G, Baell J, Xiao Y, Zhu H, Maruta H.
    Cancer Lett; 2007 Jan 08; 245(1-2):242-51. PubMed ID: 16540233
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone.
    Liu S, Goldstein RH, Scepansky EM, Rosenblatt M.
    Cancer Res; 2009 Nov 15; 69(22):8742-51. PubMed ID: 19887617
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases.
    Qian F, Engst S, Yamaguchi K, Yu P, Won KA, Mock L, Lou T, Tan J, Li C, Tam D, Lougheed J, Yakes FM, Bentzien F, Xu W, Zaks T, Wooster R, Greshock J, Joly AH.
    Cancer Res; 2009 Oct 15; 69(20):8009-16. PubMed ID: 19808973
    [Abstract] [Full Text] [Related]

  • 17. Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer.
    Ischenko I, Guba M, Yezhelyev M, Papyan A, Schmid G, Green T, Fennell M, Jauch KW, Bruns CJ.
    Angiogenesis; 2007 Oct 15; 10(3):167-82. PubMed ID: 17486419
    [Abstract] [Full Text] [Related]

  • 18. Suppression of distant pulmonary metastasis of MDA-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TIMP-2 gene transfer.
    Lee YK, So IS, Lee SC, Lee JH, Lee CW, Kim WM, Park MK, Lee ST, Park DY, Shin DY, Park CU, Kim YS.
    J Gene Med; 2005 Feb 15; 7(2):145-57. PubMed ID: 15546163
    [Abstract] [Full Text] [Related]

  • 19. SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.
    Vultur A, Buettner R, Kowolik C, Liang W, Smith D, Boschelli F, Jove R.
    Mol Cancer Ther; 2008 May 15; 7(5):1185-94. PubMed ID: 18483306
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy.
    Rucci N, Recchia I, Angelucci A, Alamanou M, Del Fattore A, Fortunati D, Susa M, Fabbro D, Bologna M, Teti A.
    J Pharmacol Exp Ther; 2006 Jul 15; 318(1):161-72. PubMed ID: 16627750
    [Abstract] [Full Text] [Related]


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