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175 related items for PubMed ID: 17309880

  • 1. Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation.
    Schneider BL, Seehus CR, Capowski EE, Aebischer P, Zhang SC, Svendsen CN.
    Hum Mol Genet; 2007 Mar 15; 16(6):651-66. PubMed ID: 17309880
    [Abstract] [Full Text] [Related]

  • 2. Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death.
    Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M.
    J Neurochem; 2006 Jul 15; 98(1):45-56. PubMed ID: 16805795
    [Abstract] [Full Text] [Related]

  • 3. Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant alpha-synucleins related to Parkinson's disease.
    Lehmensiek V, Tan EM, Liebau S, Lenk T, Zettlmeisl H, Schwarz J, Storch A.
    Neurochem Int; 2006 Apr 15; 48(5):329-40. PubMed ID: 16406146
    [Abstract] [Full Text] [Related]

  • 4. Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.
    Jiang H, Wu YC, Nakamura M, Liang Y, Tanaka Y, Holmes S, Dawson VL, Dawson TM, Ross CA, Smith WW.
    Neurobiol Aging; 2007 Nov 15; 28(11):1709-17. PubMed ID: 16978743
    [Abstract] [Full Text] [Related]

  • 5. Wild-type and mutant alpha-synuclein induce a multi-component gene expression profile consistent with shared pathophysiology in different transgenic mouse models of PD.
    Miller RM, Kiser GL, Kaysser-Kranich T, Casaceli C, Colla E, Lee MK, Palaniappan C, Federoff HJ.
    Exp Neurol; 2007 Mar 15; 204(1):421-32. PubMed ID: 17254569
    [Abstract] [Full Text] [Related]

  • 6. Plasma membrane ion permeability induced by mutant alpha-synuclein contributes to the degeneration of neural cells.
    Furukawa K, Matsuzaki-Kobayashi M, Hasegawa T, Kikuchi A, Sugeno N, Itoyama Y, Wang Y, Yao PJ, Bushlin I, Takeda A.
    J Neurochem; 2006 May 15; 97(4):1071-7. PubMed ID: 16606366
    [Abstract] [Full Text] [Related]

  • 7. Differential cytotoxicity of human wild type and mutant alpha-synuclein in human neuroblastoma SH-SY5Y cells in the presence of dopamine.
    Moussa CE, Wersinger C, Tomita Y, Sidhu A.
    Biochemistry; 2004 May 11; 43(18):5539-50. PubMed ID: 15122920
    [Abstract] [Full Text] [Related]

  • 8. Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.
    Marxreiter F, Nuber S, Kandasamy M, Klucken J, Aigner R, Burgmayer R, Couillard-Despres S, Riess O, Winkler J, Winner B.
    Eur J Neurosci; 2009 Mar 11; 29(5):879-90. PubMed ID: 19291219
    [Abstract] [Full Text] [Related]

  • 9. The embryonic midbrain directs neuronal specification of embryonic stem cells at early stages of differentiation.
    Baizabal JM, Covarrubias L.
    Dev Biol; 2009 Jan 01; 325(1):49-59. PubMed ID: 18929554
    [Abstract] [Full Text] [Related]

  • 10. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.
    Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA.
    Hum Mol Genet; 2005 Dec 15; 14(24):3801-11. PubMed ID: 16239241
    [Abstract] [Full Text] [Related]

  • 11. Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons.
    Ko JY, Park CH, Koh HC, Cho YH, Kyhm JH, Kim YS, Lee I, Lee YS, Lee SH.
    J Neurochem; 2007 Nov 15; 103(4):1417-29. PubMed ID: 17854346
    [Abstract] [Full Text] [Related]

  • 12. Generation of a alpha-synuclein-based rat model of Parkinson's disease.
    Recchia A, Rota D, Debetto P, Peroni D, Guidolin D, Negro A, Skaper SD, Giusti P.
    Neurobiol Dis; 2008 Apr 15; 30(1):8-18. PubMed ID: 18313315
    [Abstract] [Full Text] [Related]

  • 13. Selective loss of dopaminergic neurons and formation of Lewy body-like aggregations in alpha-synuclein transgenic fly neuronal cultures.
    Park SS, Lee D.
    Eur J Neurosci; 2006 Jun 15; 23(11):2908-14. PubMed ID: 16819979
    [Abstract] [Full Text] [Related]

  • 14. Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.
    Eslamboli A, Romero-Ramos M, Burger C, Bjorklund T, Muzyczka N, Mandel RJ, Baker H, Ridley RM, Kirik D.
    Brain; 2007 Mar 15; 130(Pt 3):799-815. PubMed ID: 17303591
    [Abstract] [Full Text] [Related]

  • 15. Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
    Chu Y, Kordower JH.
    Neurobiol Dis; 2007 Jan 15; 25(1):134-49. PubMed ID: 17055279
    [Abstract] [Full Text] [Related]

  • 16. Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells.
    Qian JJ, Cheng YB, Yang YP, Mao CJ, Qin ZH, Li K, Liu CF.
    Neurosci Lett; 2008 Apr 18; 435(2):142-6. PubMed ID: 18342443
    [Abstract] [Full Text] [Related]

  • 17. Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology.
    Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M.
    Brain Res; 2009 Jan 23; 1250():232-41. PubMed ID: 18992718
    [Abstract] [Full Text] [Related]

  • 18. Generation of dopamine neurons from embryonic stem cells in the presence of the neuralizing activity of bone marrow stromal cells derived from adult mice.
    Shintani A, Nakao N, Kakishita K, Itakura T.
    J Neurosci Res; 2008 Oct 23; 86(13):2829-38. PubMed ID: 18561325
    [Abstract] [Full Text] [Related]

  • 19. Glial cell line-derived neurotrophic factor enhances in vitro differentiation of mid-/hindbrain neural progenitor cells to dopaminergic-like neurons.
    Young A, Assey KS, Sturkie CD, West FD, Machacek DW, Stice SL.
    J Neurosci Res; 2010 Nov 15; 88(15):3222-32. PubMed ID: 20857516
    [Abstract] [Full Text] [Related]

  • 20. Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage.
    Lev N, Melamed E, Offen D.
    Neurosci Lett; 2006 May 15; 399(1-2):27-32. PubMed ID: 16584840
    [Abstract] [Full Text] [Related]

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