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299 related items for PubMed ID: 17312448

  • 1. Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats.
    Jiang BH, Tawara S, Abe K, Takaki A, Fukumoto Y, Shimokawa H.
    J Cardiovasc Pharmacol; 2007 Feb; 49(2):85-9. PubMed ID: 17312448
    [Abstract] [Full Text] [Related]

  • 2. Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats.
    Abe K, Shimokawa H, Morikawa K, Uwatoku T, Oi K, Matsumoto Y, Hattori T, Nakashima Y, Kaibuchi K, Sueishi K, Takeshit A.
    Circ Res; 2004 Feb 20; 94(3):385-93. PubMed ID: 14670839
    [Abstract] [Full Text] [Related]

  • 3. Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.
    Nagaoka T, Fagan KA, Gebb SA, Morris KG, Suzuki T, Shimokawa H, McMurtry IF, Oka M.
    Am J Respir Crit Care Med; 2005 Mar 01; 171(5):494-9. PubMed ID: 15563635
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of rho kinase attenuates high flow induced pulmonary hypertension in rats.
    Li FH, Xia W, Li AW, Zhao CF, Sun RP.
    Chin Med J (Engl); 2007 Jan 05; 120(1):22-9. PubMed ID: 17254483
    [Abstract] [Full Text] [Related]

  • 5. Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats.
    Tawara S, Fukumoto Y, Shimokawa H.
    J Cardiovasc Pharmacol; 2007 Aug 05; 50(2):195-200. PubMed ID: 17703136
    [Abstract] [Full Text] [Related]

  • 6. Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats.
    Li F, Xia W, Li A, Zhao C, Sun R.
    Pharmacol Res; 2007 Jan 05; 55(1):64-71. PubMed ID: 17127075
    [Abstract] [Full Text] [Related]

  • 7. [Fasudil reverses monocrotaline-induced pulmonary hypertension in rats].
    Jiang H, Guan RJ, Wang HY.
    Zhonghua Xin Xue Guan Bing Za Zhi; 2013 Mar 05; 41(3):239-44. PubMed ID: 23879951
    [Abstract] [Full Text] [Related]

  • 8. Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency.
    Gupta N, Rashid J, Nozik-Grayck E, McMurtry IF, Stenmark KR, Ahsan F.
    Mol Pharm; 2017 Mar 06; 14(3):830-841. PubMed ID: 28165252
    [Abstract] [Full Text] [Related]

  • 9. Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension.
    Gupta V, Gupta N, Shaik IH, Mehvar R, McMurtry IF, Oka M, Nozik-Grayck E, Komatsu M, Ahsan F.
    J Control Release; 2013 Apr 28; 167(2):189-99. PubMed ID: 23353807
    [Abstract] [Full Text] [Related]

  • 10. Fasudil and DETA NONOate, Loaded in a Peptide-Modified Liposomal Carrier, Slow PAH Progression upon Pulmonary Delivery.
    Rashid J, Nahar K, Raut S, Keshavarz A, Ahsan F.
    Mol Pharm; 2018 May 07; 15(5):1755-1765. PubMed ID: 29528655
    [Abstract] [Full Text] [Related]

  • 11. Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil.
    Mouchaers KT, Schalij I, de Boer MA, Postmus PE, van Hinsbergh VW, van Nieuw Amerongen GP, Vonk Noordegraaf A, van der Laarse WJ.
    Eur Respir J; 2010 Oct 07; 36(4):800-7. PubMed ID: 20351034
    [Abstract] [Full Text] [Related]

  • 12. The beneficial impact of fasudil and sildenafil on monocrotaline-induced pulmonary hypertension in rats: a hemodynamic and biochemical study.
    Jasińska-Stroschein M, Owczarek J, Łuczak A, Orszulak-Michalak D.
    Pharmacology; 2013 Oct 07; 91(3-4):178-84. PubMed ID: 23428587
    [Abstract] [Full Text] [Related]

  • 13. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats.
    Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF.
    Circ Res; 2007 Mar 30; 100(6):923-9. PubMed ID: 17332430
    [Abstract] [Full Text] [Related]

  • 14. Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension.
    Schwenke DO, Pearson JT, Sonobe T, Ishibashi-Ueda H, Shimouchi A, Kangawa K, Umetani K, Shirai M.
    J Appl Physiol (1985); 2011 Apr 30; 110(4):901-8. PubMed ID: 21212241
    [Abstract] [Full Text] [Related]

  • 15. Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice.
    Abe K, Tawara S, Oi K, Hizume T, Uwatoku T, Fukumoto Y, Kaibuchi K, Shimokawa H.
    J Cardiovasc Pharmacol; 2006 Dec 30; 48(6):280-5. PubMed ID: 17204906
    [Abstract] [Full Text] [Related]

  • 16. Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors.
    Fukumoto Y, Tawara S, Shimokawa H.
    Tohoku J Exp Med; 2007 Apr 30; 211(4):309-20. PubMed ID: 17409670
    [Abstract] [Full Text] [Related]

  • 17. Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.
    Badejo AM, Dhaliwal JS, Casey DB, Gallen TB, Greco AJ, Kadowitz PJ.
    Am J Physiol Lung Cell Mol Physiol; 2008 Nov 30; 295(5):L828-36. PubMed ID: 18689606
    [Abstract] [Full Text] [Related]

  • 18. The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat.
    Pankey EA, Byun RJ, Smith WB, Bhartiya M, Bueno FR, Badejo AM, Stasch JP, Murthy SN, Nossaman BD, Kadowitz PJ.
    Can J Physiol Pharmacol; 2012 Jul 30; 90(7):825-35. PubMed ID: 22591047
    [Abstract] [Full Text] [Related]

  • 19. Effects of fasudil, a Rho-kinase inhibitor, on myocardial preconditioning in anesthetized rats.
    Demiryürek S, Kara AF, Celik A, Babül A, Tarakçioglu M, Demiryürek AT.
    Eur J Pharmacol; 2005 Dec 19; 527(1-3):129-40. PubMed ID: 16307738
    [Abstract] [Full Text] [Related]

  • 20. Combination therapy with fasudil and sildenafil ameliorates monocrotaline-induced pulmonary hypertension and survival in rats.
    Elias-Al-Mamun M, Satoh K, Tanaka S, Shimizu T, Nergui S, Miyata S, Fukumoto Y, Shimokawa H.
    Circ J; 2014 Dec 19; 78(4):967-76. PubMed ID: 24553194
    [Abstract] [Full Text] [Related]

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