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Journal Abstract Search
216 related items for PubMed ID: 17316604
1. Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species. Rowland SE, Clark P, Gordon R, Mullen AK, Guay J, Dufresne L, Brideau C, Cote B, Ducharme Y, Mancini J, Chan CC, Audoly L, Xu D. Eur J Pharmacol; 2007 Apr 10; 560(2-3):216-24. PubMed ID: 17316604 [Abstract] [Full Text] [Related]
2. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Riendeau D, Percival MD, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Falgueyret JP, Ford-Hutchinson AW, Gordon R, Greig G, Gresser M, Guay J, Kargman S, Léger S, Mancini JA, O'Neill G, Ouellet M, Rodger IW, Thérien M, Wang Z, Webb JK, Wong E, Chan CC. Br J Pharmacol; 1997 May 10; 121(1):105-17. PubMed ID: 9146894 [Abstract] [Full Text] [Related]
4. Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors. Gierse J, Nickols M, Leahy K, Warner J, Zhang Y, Cortes-Burgos L, Carter J, Seibert K, Masferrer J. Eur J Pharmacol; 2008 Jun 24; 588(1):93-8. PubMed ID: 18457826 [Abstract] [Full Text] [Related]
13. Discovery of a novel COX-2 inhibitor as an orally potent anti-pyretic and anti-inflammatory drug: design, synthesis, and structure-activity relationship. Hayashi S, Sumi Y, Ueno N, Murase A, Takada J. Biochem Pharmacol; 2011 Oct 01; 82(7):755-68. PubMed ID: 21741371 [Abstract] [Full Text] [Related]
15. In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives. Shin SS, Byun Y, Lim KM, Choi JK, Lee KW, Moh JH, Kim JK, Jeong YS, Kim JY, Choi YH, Koh HJ, Park YH, Oh YI, Noh MS, Chung S. J Med Chem; 2004 Feb 12; 47(4):792-804. PubMed ID: 14761182 [Abstract] [Full Text] [Related]