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136 related items for PubMed ID: 17318886

  • 1. Increased dopamine D2(High) receptors in amphetamine-sensitized rats, measured by the agonist [(3)H](+)PHNO.
    Seeman P, McCormick PN, Kapur S.
    Synapse; 2007 May; 61(5):263-7. PubMed ID: 17318886
    [Abstract] [Full Text] [Related]

  • 2. Amphetamine-sensitized animals show a marked increase in dopamine D2 high receptors occupied by endogenous dopamine, even in the absence of acute challenges.
    Seeman P, Tallerico T, Ko F, Tenn C, Kapur S.
    Synapse; 2002 Dec 15; 46(4):235-9. PubMed ID: 12373738
    [Abstract] [Full Text] [Related]

  • 3. In vivo characterization of the pharmacokinetics and pharmacological properties of [11C]-(+)-PHNO in rats using an intracerebral beta-sensitive system.
    Galineau L, Wilson AA, Garcia A, Houle S, Kapur S, Ginovart N.
    Synapse; 2006 Aug 15; 60(2):172-83. PubMed ID: 16715499
    [Abstract] [Full Text] [Related]

  • 4. Dopamine D2High receptors measured ex vivo are elevated in amphetamine-sensitized animals.
    Seeman P.
    Synapse; 2009 Mar 15; 63(3):186-92. PubMed ID: 19086090
    [Abstract] [Full Text] [Related]

  • 5. Dopamine agonist radioligand binds to both D2High and D2Low receptors, explaining why alterations in D2High are not detected in human brain scans.
    Seeman P.
    Synapse; 2012 Jan 15; 66(1):88-93. PubMed ID: 21954082
    [Abstract] [Full Text] [Related]

  • 6. Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO.
    Seeman P, Battaglia G, Corti C, Corsi M, Bruno V.
    Synapse; 2009 Mar 15; 63(3):247-51. PubMed ID: 19084908
    [Abstract] [Full Text] [Related]

  • 7. Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo.
    McCormick PN, Kapur S, Seeman P, Wilson AA.
    Nucl Med Biol; 2008 Jan 15; 35(1):11-7. PubMed ID: 18158938
    [Abstract] [Full Text] [Related]

  • 8. Repeated administration of a dopamine D1 receptor agonist reverses the increased proportions of striatal dopamine D1High and D2High receptors in methamphetamine-sensitized rats.
    Shuto T, Seeman P, Kuroiwa M, Nishi A.
    Eur J Neurosci; 2008 May 15; 27(10):2551-7. PubMed ID: 18489579
    [Abstract] [Full Text] [Related]

  • 9. Ex vivo [11C]-(+)-PHNO binding is unchanged in animal models displaying increased high-affinity states of the D2 receptor in vitro.
    McCormick PN, Kapur S, Reckless G, Wilson AA.
    Synapse; 2009 Nov 15; 63(11):998-1009. PubMed ID: 19598174
    [Abstract] [Full Text] [Related]

  • 10. In vitro and in vivo comparison of [³H](+)-PHNO and [³H]raclopride binding to rat striatum and lobes 9 and 10 of the cerebellum: a method to distinguish dopamine D₃ from D₂ receptor sites.
    Kiss B, Horti F, Bobok A.
    Synapse; 2011 Jun 15; 65(6):467-78. PubMed ID: 20936685
    [Abstract] [Full Text] [Related]

  • 11. Antiparkinson therapeutic potencies correlate with their affinities at dopamine D2(High) receptors.
    Seeman P.
    Synapse; 2007 Dec 15; 61(12):1013-8. PubMed ID: 17853435
    [Abstract] [Full Text] [Related]

  • 12. Dopamine receptors labelled by PHNO.
    Seeman P, Ulpian C, Larsen RD, Anderson PS.
    Synapse; 1993 Aug 15; 14(4):254-62. PubMed ID: 7902615
    [Abstract] [Full Text] [Related]

  • 13. Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography.
    Ginovart N, Galineau L, Willeit M, Mizrahi R, Bloomfield PM, Seeman P, Houle S, Kapur S, Wilson AA.
    J Neurochem; 2006 May 15; 97(4):1089-103. PubMed ID: 16606355
    [Abstract] [Full Text] [Related]

  • 14. Antiparkinson concentrations of pramipexole and PHNO occupy dopamine D2(high) and D3(high) receptors.
    Seeman P, Ko F, Willeit M, McCormick P, Ginovart N.
    Synapse; 2005 Nov 15; 58(2):122-8. PubMed ID: 16088951
    [Abstract] [Full Text] [Related]

  • 15. Dopamine displaces [3H]domperidone from high-affinity sites of the dopamine D2 receptor, but not [3H]raclopride or [3H]spiperone in isotonic medium: Implications for human positron emission tomography.
    Seeman P, Tallerico T, Ko F.
    Synapse; 2003 Sep 15; 49(4):209-15. PubMed ID: 12827639
    [Abstract] [Full Text] [Related]

  • 16. Elevated dopamine D2High receptors in alpha-1b-adrenoceptor knockout supersensitive mice.
    Tassin JP, Torrens Y, Salomon L, Lanteri C, Seeman P.
    Synapse; 2007 Jul 15; 61(7):569-72. PubMed ID: 17447259
    [Abstract] [Full Text] [Related]

  • 17. Dopamine D2(High) receptors on intact cells.
    Seeman P.
    Synapse; 2008 Apr 15; 62(4):314-8. PubMed ID: 18241049
    [Abstract] [Full Text] [Related]

  • 18. Amphetamine-induced locomotion, behavioral sensitization to amphetamine, and striatal D2 receptor function in rats with high or low spontaneous exploratory activity: differences in the role of locus coeruleus.
    Alttoa A, Eller M, Herm L, Rinken A, Harro J.
    Brain Res; 2007 Feb 02; 1131(1):138-48. PubMed ID: 17156751
    [Abstract] [Full Text] [Related]

  • 19. Dopamine D2 receptors mapped in rat brain with [3H](+)PHNO.
    Nobrega JN, Seeman P.
    Synapse; 1994 Jul 02; 17(3):167-72. PubMed ID: 7974199
    [Abstract] [Full Text] [Related]

  • 20. Alcohol-withdrawn animals have a prolonged increase in dopamine D2high receptors, reversed by general anesthesia: relation to relapse?
    Seeman P, Tallerico T, Ko F.
    Synapse; 2004 May 02; 52(2):77-83. PubMed ID: 15034913
    [Abstract] [Full Text] [Related]

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