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207 related items for PubMed ID: 17319785

  • 1. Hsp90 inhibitor geldanamycin increases the sensitivity of resistant ovarian adenocarcinoma cell line A2780cis to cisplatin.
    Solár P, Horváth V, Kleban J, Koval' J, Solárová Z, Kozubík A, Fedorocko P.
    Neoplasma; 2007; 54(2):127-30. PubMed ID: 17319785
    [Abstract] [Full Text] [Related]

  • 2. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
    Schwock J, Pham NA, Cao MP, Hedley DW.
    Cancer Chemother Pharmacol; 2008 Apr; 61(4):669-81. PubMed ID: 17579866
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4'fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells.
    Solárová Z, Kello M, Varinská L, Budovská M, Solár P.
    Biomed Pharmacother; 2017 Jan; 85():463-471. PubMed ID: 27887849
    [Abstract] [Full Text] [Related]

  • 4. High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro.
    Kozubík A, Horváth V, Svihálková-Sindlerová L, Soucek K, Hofmanová J, Sova P, Kroutil A, Zák F, Mistr A, Turánek J.
    Biochem Pharmacol; 2005 Feb 01; 69(3):373-83. PubMed ID: 15652229
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of thymidine phosphorylase expression by using an HSP90 inhibitor potentiates the cytotoxic effect of cisplatin in non-small-cell lung cancer cells.
    Weng SH, Tseng SC, Huang YC, Chen HJ, Lin YW.
    Biochem Pharmacol; 2012 Jul 01; 84(1):126-36. PubMed ID: 22480737
    [Abstract] [Full Text] [Related]

  • 6. Proteome-wide changes induced by the Hsp90 inhibitor, geldanamycin in anaplastic large cell lymphoma cells.
    Schumacher JA, Crockett DK, Elenitoba-Johnson KS, Lim MS.
    Proteomics; 2007 Aug 01; 7(15):2603-16. PubMed ID: 17610208
    [Abstract] [Full Text] [Related]

  • 7. Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells.
    Horváth V, Blanárová O, Svihálková-Sindlerová L, Soucek K, Hofmanová J, Sova P, Kroutil A, Fedorocko P, Kozubík A.
    Gynecol Oncol; 2006 Jul 01; 102(1):32-40. PubMed ID: 16364413
    [Abstract] [Full Text] [Related]

  • 8. The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9.
    Georgakis GV, Li Y, Younes A.
    Br J Haematol; 2006 Oct 01; 135(1):68-71. PubMed ID: 16925576
    [Abstract] [Full Text] [Related]

  • 9. Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin.
    Bagatell R, Beliakoff J, David CL, Marron MT, Whitesell L.
    Int J Cancer; 2005 Jan 10; 113(2):179-88. PubMed ID: 15455381
    [Abstract] [Full Text] [Related]

  • 10. Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells.
    Kurashina R, Ohyashiki JH, Kobayashi C, Hamamura R, Zhang Y, Hirano T, Ohyashiki K.
    Cancer Lett; 2009 Oct 18; 284(1):62-70. PubMed ID: 19464103
    [Abstract] [Full Text] [Related]

  • 11. Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation.
    Yun BG, Matts RL.
    Cell Signal; 2005 Dec 18; 17(12):1477-85. PubMed ID: 15935620
    [Abstract] [Full Text] [Related]

  • 12. The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
    Leng AM, Liu T, Yang J, Cui JF, Li XH, Zhu YN, Xiong T, Zhang G, Chen Y.
    Cell Biol Int; 2012 Oct 01; 36(10):893-9. PubMed ID: 22694478
    [Abstract] [Full Text] [Related]

  • 13. [Effect of HSP90 function inhibited on the telomerase and P53 mutant in breast cancer cells].
    Li X, Deng HY.
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2008 Mar 01; 39(2):181-3. PubMed ID: 18630678
    [Abstract] [Full Text] [Related]

  • 14. The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
    Ui T, Morishima K, Saito S, Sakuma Y, Fujii H, Hosoya Y, Ishikawa S, Aburatani H, Fukayama M, Niki T, Yasuda Y.
    Oncol Rep; 2014 Feb 01; 31(2):619-24. PubMed ID: 24317439
    [Abstract] [Full Text] [Related]

  • 15. Geldanamycin, an inhibitor of Hsp90, increases paclitaxel-mediated toxicity in ovarian cancer cells through sustained activation of the p38/H2AX axis.
    Mo Q, Zhang Y, Jin X, Gao Y, Wu Y, Hao X, Gao Q, Chen P.
    Tumour Biol; 2016 Nov 01; 37(11):14745-14755. PubMed ID: 27629142
    [Abstract] [Full Text] [Related]

  • 16. Potent cytotoxic C-11 modified geldanamycin analogues.
    Tian ZQ, Wang Z, MacMillan KS, Zhou Y, Carreras CW, Mueller T, Myles DC, Liu Y.
    J Med Chem; 2009 May 28; 52(10):3265-73. PubMed ID: 19405528
    [Abstract] [Full Text] [Related]

  • 17. Enhancement of cisplatin sensitivity by NSC109268 in budding yeast and human cancer cells is associated with inhibition of S-phase progression.
    Jain D, Patel N, Shelton M, Basu A, Roque R, Siede W.
    Cancer Chemother Pharmacol; 2010 Oct 28; 66(5):945-52. PubMed ID: 20101404
    [Abstract] [Full Text] [Related]

  • 18. Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
    Al Shaer L, Walsby E, Gilkes A, Tonks A, Walsh V, Mills K, Burnett A, Rowntree C.
    Br J Haematol; 2008 May 28; 141(4):483-93. PubMed ID: 18373709
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and anticancer activity of geldanamycin derivatives derived from biosynthetically generated metabolites.
    Lee K, Ryu JS, Jin Y, Kim W, Kaur N, Chung SJ, Jeon YJ, Park JT, Bang JS, Lee HS, Kim TY, Lee JJ, Hong YS.
    Org Biomol Chem; 2008 Jan 21; 6(2):340-8. PubMed ID: 18175003
    [Abstract] [Full Text] [Related]

  • 20. HSP90 inhibitor 17AAG causes apoptosis in ATRA-resistant acute promyelocytic leukemia cells.
    Meyer PN, Roychowdhury S, Kini AR, Alkan S.
    Leuk Res; 2008 Jan 21; 32(1):143-9. PubMed ID: 17617451
    [Abstract] [Full Text] [Related]

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