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182 related items for PubMed ID: 17321230

  • 1. Calcitonin induces podosome disassembly and detachment of osteoclasts by modulating Pyk2 and Src activities.
    Shyu JF, Shih C, Tseng CY, Lin CH, Sun DT, Liu HT, Tsung HC, Chen TH, Lu RB.
    Bone; 2007 May; 40(5):1329-42. PubMed ID: 17321230
    [Abstract] [Full Text] [Related]

  • 2. Osteoprotegerin disrupts peripheral adhesive structures of osteoclasts by modulating Pyk2 and Src activities.
    Zhao H, Liu X, Zou H, Dai N, Yao L, Zhang X, Gao Q, Liu W, Gu J, Yuan Y, Bian J, Liu Z.
    Cell Adh Migr; 2016 May 03; 10(3):299-309. PubMed ID: 26743491
    [Abstract] [Full Text] [Related]

  • 3. PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase.
    Duong LT, Lakkakorpi PT, Nakamura I, Machwate M, Nagy RM, Rodan GA.
    J Clin Invest; 1998 Sep 01; 102(5):881-92. PubMed ID: 9727056
    [Abstract] [Full Text] [Related]

  • 4. Osteoprotegerin induces podosome disassembly in osteoclasts through calcium, ERK, and p38 MAPK signaling pathways.
    Zhao H, Liu X, Zou H, Dai N, Yao L, Gao Q, Liu W, Gu J, Yuan Y, Bian J, Liu Z.
    Cytokine; 2015 Feb 01; 71(2):199-206. PubMed ID: 25461399
    [Abstract] [Full Text] [Related]

  • 5. Calcitonin induces dephosphorylation of Pyk2 and phosphorylation of focal adhesion kinase in osteoclasts.
    Zhang Z, Neff L, Bothwell AL, Baron R, Horne WC.
    Bone; 2002 Sep 01; 31(3):359-65. PubMed ID: 12231407
    [Abstract] [Full Text] [Related]

  • 6. Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts.
    Luxenburg C, Parsons JT, Addadi L, Geiger B.
    J Cell Sci; 2006 Dec 01; 119(Pt 23):4878-88. PubMed ID: 17105771
    [Abstract] [Full Text] [Related]

  • 7. Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: roles of calcium, Src, Rho kinase, and the cytoskeleton.
    Wu SS, Jácamo RO, Vong SK, Rozengurt E.
    Cell Signal; 2006 Nov 01; 18(11):1932-40. PubMed ID: 16574377
    [Abstract] [Full Text] [Related]

  • 8. PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption.
    Lakkakorpi PT, Bett AJ, Lipfert L, Rodan GA, Duong LT.
    J Biol Chem; 2003 Mar 28; 278(13):11502-12. PubMed ID: 12514172
    [Abstract] [Full Text] [Related]

  • 9. Organization of cytoskeletal F-actin, G-actin, and gelsolin in the adhesion structures in cultured osteoclast.
    Akisaka T, Yoshida H, Inoue S, Shimizu K.
    J Bone Miner Res; 2001 Jul 28; 16(7):1248-55. PubMed ID: 11450700
    [Abstract] [Full Text] [Related]

  • 10. Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation.
    Sun CK, Man K, Ng KT, Ho JW, Lim ZX, Cheng Q, Lo CM, Poon RT, Fan ST.
    Carcinogenesis; 2008 Nov 28; 29(11):2096-105. PubMed ID: 18765415
    [Abstract] [Full Text] [Related]

  • 11. Podosome and sealing zone: specificity of the osteoclast model.
    Jurdic P, Saltel F, Chabadel A, Destaing O.
    Eur J Cell Biol; 2006 Apr 28; 85(3-4):195-202. PubMed ID: 16546562
    [Abstract] [Full Text] [Related]

  • 12. Myristoleic acid inhibits osteoclast formation and bone resorption by suppressing the RANKL activation of Src and Pyk2.
    Kwon JO, Jin WJ, Kim B, Kim HH, Lee ZH.
    Eur J Pharmacol; 2015 Dec 05; 768():189-98. PubMed ID: 26528796
    [Abstract] [Full Text] [Related]

  • 13. Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice.
    Gil-Henn H, Destaing O, Sims NA, Aoki K, Alles N, Neff L, Sanjay A, Bruzzaniti A, De Camilli P, Baron R, Schlessinger J.
    J Cell Biol; 2007 Sep 10; 178(6):1053-64. PubMed ID: 17846174
    [Abstract] [Full Text] [Related]

  • 14. Evidence that activation of ASIC1a by acidosis increases osteoclast migration and adhesion by modulating integrin/Pyk2/Src signaling pathway.
    Li X, Ye JX, Xu MH, Zhao MD, Yuan FL.
    Osteoporos Int; 2017 Jul 10; 28(7):2221-2231. PubMed ID: 28462470
    [Abstract] [Full Text] [Related]

  • 15. Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts.
    Bruzzaniti A, Neff L, Sandoval A, Du L, Horne WC, Baron R.
    Mol Cell Biol; 2009 Jul 10; 29(13):3644-56. PubMed ID: 19380485
    [Abstract] [Full Text] [Related]

  • 16. Src kinase activity is essential for osteoclast function.
    Miyazaki T, Sanjay A, Neff L, Tanaka S, Horne WC, Baron R.
    J Biol Chem; 2004 Apr 23; 279(17):17660-6. PubMed ID: 14739300
    [Abstract] [Full Text] [Related]

  • 17. Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks.
    Okumura S, Mizoguchi T, Sato N, Yamaki M, Kobayashi Y, Yamauchi H, Ozawa H, Udagawa N, Takahashi N.
    Bone; 2006 Oct 23; 39(4):684-93. PubMed ID: 16774853
    [Abstract] [Full Text] [Related]

  • 18. The molecular dynamics of osteoclast adhesions.
    Luxenburg C, Addadi L, Geiger B.
    Eur J Cell Biol; 2006 Apr 23; 85(3-4):203-11. PubMed ID: 16360241
    [Abstract] [Full Text] [Related]

  • 19. Src and FAK mediate cell-matrix adhesion-dependent activation of Met during transformation of breast epithelial cells.
    Hui AY, Meens JA, Schick C, Organ SL, Qiao H, Tremblay EA, Schaeffer E, Uniyal S, Chan BM, Elliott BE.
    J Cell Biochem; 2009 Aug 15; 107(6):1168-81. PubMed ID: 19533669
    [Abstract] [Full Text] [Related]

  • 20. Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone.
    Lakkakorpi PT, Nakamura I, Nagy RM, Parsons JT, Rodan GA, Duong LT.
    J Biol Chem; 1999 Feb 19; 274(8):4900-7. PubMed ID: 9988732
    [Abstract] [Full Text] [Related]

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