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Journal Abstract Search

144 related items for PubMed ID: 17324575

  • 1. Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity.
    Ciliberti N, Manfredini S, Angusti A, Durini E, Solaroli N, Vertuani S, Buzzoni L, Bonache MC, Ben-Shalom E, Karlsson A, Saada A, Balzarini J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):3065-81. PubMed ID: 17324575
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  • 2. 2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase.
    Balzarinia J, Degrève B, Zhu C, Durini E, Porcu L, De Clercq E, Karlsson A, Manfredini S.
    Biochem Pharmacol; 2001 Mar 15; 61(6):727-32. PubMed ID: 11266658
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  • 3. N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.
    Hernandez AI, Familiar O, Negri A, Rodríguez-Barrios F, Gago F, Karlsson A, Camarasa MJ, Balzarini J, Pérez-Pérez MJ.
    J Med Chem; 2006 Dec 28; 49(26):7766-73. PubMed ID: 17181158
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  • 6. 3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase.
    Van Poecke S, Negri A, Gago F, Van Daele I, Solaroli N, Karlsson A, Balzarini J, Van Calenbergh S.
    J Med Chem; 2010 Apr 08; 53(7):2902-12. PubMed ID: 20218622
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  • 8. Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA.
    Curbo S, Johansson M, Balzarini J, Lewis LD, Karlsson A.
    Exp Cell Res; 2009 Sep 10; 315(15):2539-43. PubMed ID: 19481540
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  • 9. Retained sensitivity to cytotoxic pyrimidine nucleoside analogs in thymidine kinase 2 deficient human fibroblasts.
    Bjerke M, Solaroli N, Lesko N, Balzarini J, Johansson M, Karlsson A.
    Nucleosides Nucleotides Nucleic Acids; 2010 Jan 10; 29(1):1-13. PubMed ID: 20391188
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  • 11. Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors.
    Van Poecke S, Negri A, Janssens J, Solaroli N, Karlsson A, Gago F, Balzarini J, Van Calenbergh S.
    Org Biomol Chem; 2011 Feb 07; 9(3):892-901. PubMed ID: 21127790
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  • 12. The design, synthesis and properties of highly potent and selective inhibitors of herpes simplex virus types 1 and 2 thymidine kinase.
    Martin JA, Thomas GJ, Merrett JH, Lambert RW, Bushnell DJ, Dunsdon SJ, Freeman AC, Hopkins RA, Johns IR, Keech E, Simmonite H, Kai-In PW, Holland M.
    Antivir Chem Chemother; 1998 Jan 07; 9(1):1-8. PubMed ID: 9875371
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  • 13. Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors.
    Kuramochi K, Fukudome K, Kuriyama I, Takeuchi T, Sato Y, Kamisuki S, Tsubaki K, Sugawara F, Yoshida H, Mizushina Y.
    Bioorg Med Chem; 2009 Oct 15; 17(20):7227-38. PubMed ID: 19767211
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  • 14. The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: synthesis, cytostatic, and antiviral activity evaluations.
    Gazivoda T, Raić-Malić S, Marjanović M, Kralj M, Pavelić K, Balzarini J, De Clercq E, Mintas M.
    Bioorg Med Chem; 2007 Jan 15; 15(2):749-58. PubMed ID: 17092728
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  • 15. Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications.
    Priego EM, Karlsson A, Gago F, Camarasa MJ, Balzarini J, Pérez-Pérez MJ.
    Curr Pharm Des; 2012 Jan 15; 18(20):2981-94. PubMed ID: 22571666
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  • 16. Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.
    Manfredini S, Baraldi PG, Durini E, Porcu L, Angusti A, Vertuani S, Solaroli N, De Clercq E, Karlsson A, Balzarini J.
    Bioorg Med Chem Lett; 2001 May 21; 11(10):1329-32. PubMed ID: 11392548
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  • 17. Substrate/inhibitor properties of human deoxycytidine kinase (dCK) and thymidine kinases (TK1 and TK2) towards the sugar moiety of nucleosides, including O'-alkyl analogues.
    Kierdaszuk B, Krawiec K, Kazimierczuk Z, Jacobsson U, Johansson NG, Munch-Petersen B, Eriksson S, Shugar D.
    Nucleosides Nucleotides; 1999 Aug 21; 18(8):1883-903. PubMed ID: 10478487
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  • 18. The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.
    Balzarini J, Celen S, Karlsson A, de Groot T, Verbruggen A, Bormans G.
    Antivir Chem Chemother; 2006 Aug 21; 17(1):17-23. PubMed ID: 16542002
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  • 19. Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR.
    Andrianov V, Gailite V, Lola D, Loza E, Semenikhina V, Kalvinsh I, Finn P, Petersen KD, Ritchie JW, Khan N, Tumber A, Collins LS, Vadlamudi SM, Björkling F, Sehested M.
    Eur J Med Chem; 2009 Mar 21; 44(3):1067-85. PubMed ID: 18672316
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  • 20. Expression of deoxynucleoside kinases and 5'-nucleotidases in mouse tissues: implications for mitochondrial toxicity.
    Rylova SN, Mirzaee S, Albertioni F, Eriksson S.
    Biochem Pharmacol; 2007 Jun 30; 74(1):169-75. PubMed ID: 17493587
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