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Journal Abstract Search


588 related items for PubMed ID: 17325032

  • 1. Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.
    Flügel D, Görlach A, Michiels C, Kietzmann T.
    Mol Cell Biol; 2007 May; 27(9):3253-65. PubMed ID: 17325032
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of the von Hippel-Lindau protein (VHL) by protein kinase CK2 reduces its protein stability and affects p53 and HIF-1alpha mediated transcription.
    Ampofo E, Kietzmann T, Zimmer A, Jakupovic M, Montenarh M, Götz C.
    Int J Biochem Cell Biol; 2010 Oct; 42(10):1729-35. PubMed ID: 20637892
    [Abstract] [Full Text] [Related]

  • 3. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 4. Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.
    Ader I, Brizuela L, Bouquerel P, Malavaud B, Cuvillier O.
    Cancer Res; 2008 Oct 15; 68(20):8635-42. PubMed ID: 18922940
    [Abstract] [Full Text] [Related]

  • 5. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 6. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
    [Abstract] [Full Text] [Related]

  • 7. Hypoxia-inducible factor 1α mediates the down-regulation of superoxide dismutase 2 in von Hippel-Lindau deficient renal clear cell carcinoma.
    Gao YH, Li CX, Shen SM, Li H, Chen GQ, Wei Q, Wang LS.
    Biochem Biophys Res Commun; 2013 May 24; 435(1):46-51. PubMed ID: 23611775
    [Abstract] [Full Text] [Related]

  • 8. Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system.
    Ni J, Ni A.
    PLoS One; 2021 May 24; 16(7):e0248019. PubMed ID: 34329303
    [Abstract] [Full Text] [Related]

  • 9. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha.
    Kong X, Lin Z, Liang D, Fath D, Sang N, Caro J.
    Mol Cell Biol; 2006 Mar 24; 26(6):2019-28. PubMed ID: 16507982
    [Abstract] [Full Text] [Related]

  • 10. Topotecan blocks hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells.
    Beppu K, Nakamura K, Linehan WM, Rapisarda A, Thiele CJ.
    Cancer Res; 2005 Jun 01; 65(11):4775-81. PubMed ID: 15930297
    [Abstract] [Full Text] [Related]

  • 11. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity.
    Foxler DE, Bridge KS, James V, Webb TM, Mee M, Wong SC, Feng Y, Constantin-Teodosiu D, Petursdottir TE, Bjornsson J, Ingvarsson S, Ratcliffe PJ, Longmore GD, Sharp TV.
    Nat Cell Biol; 2012 Jan 29; 14(2):201-8. PubMed ID: 22286099
    [Abstract] [Full Text] [Related]

  • 12. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.
    Mottet D, Dumont V, Deccache Y, Demazy C, Ninane N, Raes M, Michiels C.
    J Biol Chem; 2003 Aug 15; 278(33):31277-85. PubMed ID: 12764143
    [Abstract] [Full Text] [Related]

  • 13. AG490 promotes HIF-1α accumulation by inhibiting its hydroxylation.
    Fernández-Sánchez R, Berzal S, Sánchez-Niño MD, Neria F, Gonçalves S, Calabia O, Tejedor A, Calzada MJ, Caramelo C, Deudero JJ, Ortiz A.
    Curr Med Chem; 2012 Aug 15; 19(23):4014-23. PubMed ID: 22709000
    [Abstract] [Full Text] [Related]

  • 14. Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning.
    Kalakech H, Tamareille S, Pons S, Godin-Ribuot D, Carmeliet P, Furber A, Martin V, Berdeaux A, Ghaleh B, Prunier F.
    J Mol Cell Cardiol; 2013 Dec 15; 65():98-104. PubMed ID: 24140799
    [Abstract] [Full Text] [Related]

  • 15. Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity.
    Park MH, Bae SS, Choi KY, Min do S.
    Exp Mol Med; 2015 Nov 27; 47(11):e196. PubMed ID: 26611735
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.
    Tanimoto K, Makino Y, Pereira T, Poellinger L.
    EMBO J; 2000 Aug 15; 19(16):4298-309. PubMed ID: 10944113
    [Abstract] [Full Text] [Related]

  • 17. RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha.
    Liu YV, Baek JH, Zhang H, Diez R, Cole RN, Semenza GL.
    Mol Cell; 2007 Jan 26; 25(2):207-17. PubMed ID: 17244529
    [Abstract] [Full Text] [Related]

  • 18. Role of the von Hippel-Lindau tumour suppressor protein in the regulation of HIF-1alpha and its oxygen-regulated transactivation domains at high cell density.
    Paltoglou SM, Roberts BJ.
    Oncogene; 2005 May 26; 24(23):3830-5. PubMed ID: 15750626
    [Abstract] [Full Text] [Related]

  • 19. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ.
    Cell Cycle; 2012 Dec 01; 11(23):4462-73. PubMed ID: 23159849
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of the glycogen synthase kinase 3β-hypoxia-inducible factor 1α pathway alleviates NLRP3-mediated pyroptosis induced by high glucose in renal tubular epithelial cells.
    Wan J, Jiang Z, Liu D, Pan S, Zhou S, Liu Z.
    Exp Physiol; 2022 Dec 01; 107(12):1493-1506. PubMed ID: 36056793
    [Abstract] [Full Text] [Related]


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