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136 related items for PubMed ID: 17327429

  • 1. PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells.
    Miele C, Raciti GA, Cassese A, Romano C, Giacco F, Oriente F, Paturzo F, Andreozzi F, Zabatta A, Troncone G, Bosch F, Pujol A, Chneiweiss H, Formisano P, Beguinot F.
    Diabetes; 2007 Mar; 56(3):622-33. PubMed ID: 17327429
    [Abstract] [Full Text] [Related]

  • 2. Adenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15.
    Cassese A, Raciti GA, Fiory F, Nigro C, Ulianich L, Castanò I, D'Esposito V, Terracciano D, Pastore L, Formisano P, Beguinot F, Miele C.
    PLoS One; 2013 Mar; 8(4):e60555. PubMed ID: 23585839
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action.
    Vigliotta G, Miele C, Santopietro S, Portella G, Perfetti A, Maitan MA, Cassese A, Oriente F, Trencia A, Fiory F, Romano C, Tiveron C, Tatangelo L, Troncone G, Formisano P, Beguinot F.
    Mol Cell Biol; 2004 Jun; 24(11):5005-15. PubMed ID: 15143191
    [Abstract] [Full Text] [Related]

  • 4. PED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1.
    Fiory F, Parrillo L, Raciti GA, Zatterale F, Nigro C, Mirra P, Falco R, Ulianich L, Di Jeso B, Formisano P, Miele C, Beguinot F.
    PLoS One; 2014 Jun; 9(12):e113655. PubMed ID: 25489735
    [Abstract] [Full Text] [Related]

  • 5. Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells.
    Condorelli G, Vigliotta G, Trencia A, Maitan MA, Caruso M, Miele C, Oriente F, Santopietro S, Formisano P, Beguinot F.
    Diabetes; 2001 Jun; 50(6):1244-52. PubMed ID: 11375323
    [Abstract] [Full Text] [Related]

  • 6. Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1.
    Ungaro P, Mirra P, Oriente F, Nigro C, Ciccarelli M, Vastolo V, Longo M, Perruolo G, Spinelli R, Formisano P, Miele C, Beguinot F.
    J Biol Chem; 2012 Dec 14; 287(51):42951-61. PubMed ID: 23105093
    [Abstract] [Full Text] [Related]

  • 7. Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
    Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A.
    Diabetes; 2011 Oct 14; 60(10):2546-59. PubMed ID: 21911744
    [Abstract] [Full Text] [Related]

  • 8. Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.
    Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M.
    J Biol Chem; 2008 Aug 01; 283(31):21769-78. PubMed ID: 18541525
    [Abstract] [Full Text] [Related]

  • 9. Regulated expression of adenosine triphosphate-sensitive potassium channel subunits in pancreatic beta-cells.
    Moritz W, Leech CA, Ferrer J, Habener JF.
    Endocrinology; 2001 Jan 01; 142(1):129-38. PubMed ID: 11145575
    [Abstract] [Full Text] [Related]

  • 10. Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation.
    Perfetti A, Oriente F, Iovino S, Alberobello AT, Barbagallo AP, Esposito I, Fiory F, Teperino R, Ungaro P, Miele C, Formisano P, Beguinot F.
    J Biol Chem; 2007 Mar 23; 282(12):8648-57. PubMed ID: 17227770
    [Abstract] [Full Text] [Related]

  • 11. Clozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance.
    Panariello F, Perruolo G, Cassese A, Giacco F, Botta G, Barbagallo AP, Muscettola G, Beguinot F, Formisano P, de Bartolomeis A.
    J Cell Physiol; 2012 Apr 23; 227(4):1485-92. PubMed ID: 21618539
    [Abstract] [Full Text] [Related]

  • 12. PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.
    Hashimoto N, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, Uchiyama Y, Akimoto K, Ohno S, Noda T, Kasuga M.
    J Clin Invest; 2005 Jan 23; 115(1):138-45. PubMed ID: 15630453
    [Abstract] [Full Text] [Related]

  • 13. Foxa2 regulates multiple pathways of insulin secretion.
    Lantz KA, Vatamaniuk MZ, Brestelli JE, Friedman JR, Matschinsky FM, Kaestner KH.
    J Clin Invest; 2004 Aug 23; 114(4):512-20. PubMed ID: 15314688
    [Abstract] [Full Text] [Related]

  • 14. Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice.
    Seino S, Iwanaga T, Nagashima K, Miki T.
    Diabetes; 2000 Mar 23; 49(3):311-8. PubMed ID: 10868950
    [Abstract] [Full Text] [Related]

  • 15. Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression.
    Oriente F, Iovino S, Cassese A, Romano C, Miele C, Troncone G, Balletta M, Perfetti A, Santulli G, Iaccarino G, Valentino R, Beguinot F, Formisano P.
    Diabetologia; 2009 Dec 23; 52(12):2642-52. PubMed ID: 19789852
    [Abstract] [Full Text] [Related]

  • 16. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.
    Bensellam M, Shi YC, Chan JY, Laybutt DR, Chae H, Abou-Samra M, Pappas EG, Thomas HE, Gilon P, Jonas JC.
    Diabetologia; 2019 Dec 23; 62(12):2273-2286. PubMed ID: 31624901
    [Abstract] [Full Text] [Related]

  • 17. Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.
    Ritzel RA, Hansen JB, Veldhuis JD, Butler PC.
    J Clin Endocrinol Metab; 2004 Feb 23; 89(2):795-805. PubMed ID: 14764798
    [Abstract] [Full Text] [Related]

  • 18. PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus.
    Condorelli G, Vigliotta G, Iavarone C, Caruso M, Tocchetti CG, Andreozzi F, Cafieri A, Tecce MF, Formisano P, Beguinot L, Beguinot F.
    EMBO J; 1998 Jul 15; 17(14):3858-66. PubMed ID: 9670003
    [Abstract] [Full Text] [Related]

  • 19. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines.
    Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E.
    J Biol Chem; 2007 Jul 06; 282(27):19575-88. PubMed ID: 17462994
    [Abstract] [Full Text] [Related]

  • 20. Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.
    Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.
    J Biol Chem; 2006 Feb 24; 281(8):5246-57. PubMed ID: 16377800
    [Abstract] [Full Text] [Related]

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