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127 related items for PubMed ID: 17331536

  • 1. Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase.
    Blaszczyk J, Li Y, Gan J, Yan H, Ji X.
    J Mol Biol; 2007 Apr 20; 368(1):161-9. PubMed ID: 17331536
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of dihydroneopterin aldolase: functional roles of the conserved active site glutamate and lysine residues.
    Wang Y, Li Y, Yan H.
    Biochemistry; 2006 Dec 26; 45(51):15232-9. PubMed ID: 17176045
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of dihydroneopterin aldolase. NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes.
    Wang Y, Li Y, Wu Y, Yan H.
    FEBS J; 2007 May 26; 274(9):2240-52. PubMed ID: 17388809
    [Abstract] [Full Text] [Related]

  • 4. Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase.
    Blaszczyk J, Lu Z, Li Y, Yan H, Ji X.
    Cell Biosci; 2014 May 26; 4(1):52. PubMed ID: 25264482
    [Abstract] [Full Text] [Related]

  • 5. Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase.
    Haussmann C, Rohdich F, Schmidt E, Bacher A, Richter G.
    J Biol Chem; 1998 Jul 10; 273(28):17418-24. PubMed ID: 9651328
    [Abstract] [Full Text] [Related]

  • 6. Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design.
    Shaw GX, Fan L, Cherry S, Shi G, Tropea JE, Ji X.
    Curr Res Struct Biol; 2023 Jul 10; 5():100095. PubMed ID: 36820301
    [Abstract] [Full Text] [Related]

  • 7. Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus.
    Hennig M, D'Arcy A, Hampele IC, Page MG, Oefner C, Dale GE.
    Nat Struct Biol; 1998 May 10; 5(5):357-62. PubMed ID: 9586996
    [Abstract] [Full Text] [Related]

  • 8. A point mutation converts dihydroneopterin aldolase to a cofactor-independent oxygenase.
    Wang Y, Scherperel G, Roberts KD, Jones AD, Reid GE, Yan H.
    J Am Chem Soc; 2006 Oct 11; 128(40):13216-23. PubMed ID: 17017801
    [Abstract] [Full Text] [Related]

  • 9. 8-Mercaptoguanine-based inhibitors of Mycobacterium tuberculosis dihydroneopterin aldolase: synthesis, in vitro inhibition and docking studies.
    Czeczot AM, Roth CD, Ducati RG, Pissinate K, Rambo RS, Timmers LFSM, Abbadi BL, Macchi FS, Pestana VZ, Basso LA, Machado P, Bizarro CV.
    J Enzyme Inhib Med Chem; 2021 Dec 11; 36(1):847-855. PubMed ID: 33752554
    [Abstract] [Full Text] [Related]

  • 10. Sweet siblings with different faces: the mechanisms of FBP and F6P aldolase, transaldolase, transketolase and phosphoketolase revisited in light of recent structural data.
    Tittmann K.
    Bioorg Chem; 2014 Dec 11; 57():263-280. PubMed ID: 25267444
    [Abstract] [Full Text] [Related]

  • 11. A vibrational structure of 7,8-dihydrobiopterin bound to dihydroneopterin aldolase.
    Deng H, Callender R, Dale GE.
    J Biol Chem; 2000 Sep 29; 275(39):30139-43. PubMed ID: 10896664
    [Abstract] [Full Text] [Related]

  • 12. Mechanism of dihydroneopterin aldolase: a molecular dynamics study of the apo enzyme and its product complex.
    Yao L, Yan H, Cukier RI.
    J Phys Chem B; 2006 Jan 26; 110(3):1443-56. PubMed ID: 16471696
    [Abstract] [Full Text] [Related]

  • 13. 6-pyruvoyltetrahydropterin synthase paralogs replace the folate synthesis enzyme dihydroneopterin aldolase in diverse bacteria.
    Pribat A, Jeanguenin L, Lara-Núñez A, Ziemak MJ, Hyde JE, de Crécy-Lagard V, Hanson AD.
    J Bacteriol; 2009 Jul 26; 191(13):4158-65. PubMed ID: 19395485
    [Abstract] [Full Text] [Related]

  • 14. Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
    Goulding CW, Apostol MI, Sawaya MR, Phillips M, Parseghian A, Eisenberg D.
    J Mol Biol; 2005 May 27; 349(1):61-72. PubMed ID: 15876368
    [Abstract] [Full Text] [Related]

  • 15. Crystal structure of the bifunctional dihydroneopterin aldolase/6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Streptococcus pneumoniae.
    Garçon A, Levy C, Derrick JP.
    J Mol Biol; 2006 Jul 14; 360(3):644-53. PubMed ID: 16781731
    [Abstract] [Full Text] [Related]

  • 16. Structure-based prediction and identification of 4-epimerization activity of phosphate sugars in class II aldolases.
    Lee SH, Hong SH, An JU, Kim KR, Kim DE, Kang LW, Oh DK.
    Sci Rep; 2017 May 16; 7(1):1934. PubMed ID: 28512318
    [Abstract] [Full Text] [Related]

  • 17. Biosynthesis of tetrahydrofolate. Stereochemistry of dihydroneopterin aldolase.
    Illarionova V, Eisenreich W, Fischer M, Haussmann C, Romisch W, Richter G, Bacher A.
    J Biol Chem; 2002 Aug 09; 277(32):28841-7. PubMed ID: 12039964
    [Abstract] [Full Text] [Related]

  • 18. Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.
    Sanders WJ, Nienaber VL, Lerner CG, McCall JO, Merrick SM, Swanson SJ, Harlan JE, Stoll VS, Stamper GF, Betz SF, Condroski KR, Meadows RP, Severin JM, Walter KA, Magdalinos P, Jakob CG, Wagner R, Beutel BA.
    J Med Chem; 2004 Mar 25; 47(7):1709-18. PubMed ID: 15027862
    [Abstract] [Full Text] [Related]

  • 19. Folate biosynthesis in higher plants. cDNA cloning, heterologous expression, and characterization of dihydroneopterin aldolases.
    Goyer A, Illarionova V, Roje S, Fischer M, Bacher A, Hanson AD.
    Plant Physiol; 2004 May 25; 135(1):103-11. PubMed ID: 15107504
    [Abstract] [Full Text] [Related]

  • 20. Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis.
    Joerger AC, Gosse C, Fessner WD, Schulz GE.
    Biochemistry; 2000 May 23; 39(20):6033-41. PubMed ID: 10821675
    [Abstract] [Full Text] [Related]


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