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325 related items for PubMed ID: 17334390

  • 1. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
    Han EK, Leverson JD, McGonigal T, Shah OJ, Woods KW, Hunter T, Giranda VL, Luo Y.
    Oncogene; 2007 Aug 16; 26(38):5655-61. PubMed ID: 17334390
    [Abstract] [Full Text] [Related]

  • 2. Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
    Veilleux A, Houde VP, Bellmann K, Marette A.
    Mol Endocrinol; 2010 Apr 16; 24(4):766-78. PubMed ID: 20203102
    [Abstract] [Full Text] [Related]

  • 3. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
    Breuleux M, Klopfenstein M, Stephan C, Doughty CA, Barys L, Maira SM, Kwiatkowski D, Lane HA.
    Mol Cancer Ther; 2009 Apr 16; 8(4):742-53. PubMed ID: 19372546
    [Abstract] [Full Text] [Related]

  • 4. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M.
    Int J Oncol; 2009 Oct 16; 35(4):731-40. PubMed ID: 19724909
    [Abstract] [Full Text] [Related]

  • 5. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May 16; 31(5):673-82. PubMed ID: 17007924
    [Abstract] [Full Text] [Related]

  • 6. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation.
    Diez H, Benitez MJ, Fernandez S, Torres-Aleman I, Garrido JJ, Wandosell F.
    Biochim Biophys Acta; 2016 Nov 16; 1863(11):2574-2583. PubMed ID: 27421985
    [Abstract] [Full Text] [Related]

  • 7. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.
    Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E.
    Mol Cancer Ther; 2015 Apr 16; 14(4):1014-23. PubMed ID: 25673820
    [Abstract] [Full Text] [Related]

  • 8. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA, Carriere A, Moreau J, Roux PP.
    Mol Cell Biol; 2010 Feb 16; 30(4):908-21. PubMed ID: 19995915
    [Abstract] [Full Text] [Related]

  • 9. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
    [Abstract] [Full Text] [Related]

  • 10. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM.
    Dev Cell; 2006 Dec 10; 11(6):859-71. PubMed ID: 17141160
    [Abstract] [Full Text] [Related]

  • 11. Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1.
    Liu Y, Fanburg BL.
    Am J Respir Cell Mol Biol; 2006 Feb 10; 34(2):182-91. PubMed ID: 16195541
    [Abstract] [Full Text] [Related]

  • 12. Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
    Copps KD, Hançer NJ, Qiu W, White MF.
    J Biol Chem; 2016 Apr 15; 291(16):8602-17. PubMed ID: 26846849
    [Abstract] [Full Text] [Related]

  • 13. Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.
    Misra UK, Pizzo SV.
    J Cell Biochem; 2012 May 15; 113(5):1488-500. PubMed ID: 22173835
    [Abstract] [Full Text] [Related]

  • 14. Rapamycin regulates the phosphorylation of rictor.
    Akcakanat A, Singh G, Hung MC, Meric-Bernstam F.
    Biochem Biophys Res Commun; 2007 Oct 19; 362(2):330-3. PubMed ID: 17707343
    [Abstract] [Full Text] [Related]

  • 15. Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
    Li W, Petrimpol M, Molle KD, Hall MN, Battegay EJ, Humar R.
    Circ Res; 2007 Jan 05; 100(1):79-87. PubMed ID: 17110594
    [Abstract] [Full Text] [Related]

  • 16. RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia.
    Mancini M, Petta S, Martinelli G, Barbieri E, Santucci MA.
    J Cell Biochem; 2010 Feb 01; 109(2):320-8. PubMed ID: 20014066
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of Akt (ser473) phosphorylation and rapamycin-resistant cell growth by knockdown of mammalian target of rapamycin with small interfering RNA in vascular endothelial growth factor receptor-1-targeting vector.
    Koide H, Asai T, Furuya K, Tsuzuku T, Kato H, Dewa T, Nango M, Maeda N, Oku N.
    Biol Pharm Bull; 2011 Feb 01; 34(5):602-8. PubMed ID: 21532145
    [Abstract] [Full Text] [Related]

  • 18. Raptor-rictor axis in TGFbeta-induced protein synthesis.
    Das F, Ghosh-Choudhury N, Mahimainathan L, Venkatesan B, Feliers D, Riley DJ, Kasinath BS, Choudhury GG.
    Cell Signal; 2008 Feb 01; 20(2):409-23. PubMed ID: 18068336
    [Abstract] [Full Text] [Related]

  • 19. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.
    Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907
    [Abstract] [Full Text] [Related]

  • 20. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
    Dan HC, Ebbs A, Pasparakis M, Van Dyke T, Basseres DS, Baldwin AS.
    J Biol Chem; 2014 Sep 05; 289(36):25227-40. PubMed ID: 24990947
    [Abstract] [Full Text] [Related]

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