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Journal Abstract Search


105 related items for PubMed ID: 1734088

  • 1. Depletion of glutathione in normal and malignant human cells in vivo by buthionine sulfoximine: clinical and biochemical results.
    O'Dwyer PJ, Hamilton TC, Young RC, LaCreta FP, Carp N, Tew KD, Padavic K, Comis RL, Ozols RF.
    J Natl Cancer Inst; 1992 Feb 19; 84(4):264-7. PubMed ID: 1734088
    [No Abstract] [Full Text] [Related]

  • 2. Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione.
    Bailey HH, Mulcahy RT, Tutsch KD, Arzoomanian RZ, Alberti D, Tombes MB, Wilding G, Pomplun M, Spriggs DR.
    J Clin Oncol; 1994 Jan 19; 12(1):194-205. PubMed ID: 8270977
    [Abstract] [Full Text] [Related]

  • 3. Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.
    O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T, Brennan J, Bookman MA, Hoffman J, Young RC, Comis RL, Ozols RF.
    J Clin Oncol; 1996 Jan 19; 14(1):249-56. PubMed ID: 8558205
    [Abstract] [Full Text] [Related]

  • 4. Time-dependent pharmacodynamic models in cancer chemotherapy: population pharmacodynamic model for glutathione depletion following modulation by buthionine sulfoximine (BSO) in a Phase I trial of melphalan and BSO.
    Gallo JM, Brennan J, Hamilton TC, Halbherr T, Laub PB, Ozols RF, O'Dwyer PJ.
    Cancer Res; 1995 Oct 15; 55(20):4507-11. PubMed ID: 7553617
    [Abstract] [Full Text] [Related]

  • 5. Depletion of glutathione in normal and malignant human cells in vivo by L-buthionine sulfoximine: possible interaction with ascorbate.
    Meister A.
    J Natl Cancer Inst; 1992 Oct 21; 84(20):1601-2. PubMed ID: 1285780
    [No Abstract] [Full Text] [Related]

  • 6. In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy.
    Siemann DW, Beyers KL.
    Br J Cancer; 1993 Dec 21; 68(6):1071-9. PubMed ID: 8260357
    [Abstract] [Full Text] [Related]

  • 7. Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan.
    Bailey HH, Ripple G, Tutsch KD, Arzoomanian RZ, Alberti D, Feierabend C, Mahvi D, Schink J, Pomplun M, Mulcahy RT, Wilding G.
    J Natl Cancer Inst; 1997 Dec 03; 89(23):1789-96. PubMed ID: 9392620
    [Abstract] [Full Text] [Related]

  • 8. The role of glutathione in drug resistance.
    Ozols RF, O'Dwyer PJ, Hamilton TC, Young RC.
    Cancer Treat Rev; 1990 Dec 03; 17 Suppl A():45-50. PubMed ID: 2092870
    [No Abstract] [Full Text] [Related]

  • 9. Buthionine sulfoximine pretreatment potentiates the effect of isolated lung perfusion with doxorubicin.
    Port JL, Hochwald SN, Wang HY, Burt ME.
    Ann Thorac Surg; 1995 Aug 03; 60(2):239-43; discussion 244. PubMed ID: 7544099
    [Abstract] [Full Text] [Related]

  • 10. Melanoma cytotoxicity of buthionine sulfoximine (BSO) alone and in combination with 3,4-dihydroxybenzylamine and melphalan.
    Prezioso JA, FitzGerald GB, Wick MM.
    J Invest Dermatol; 1992 Sep 03; 99(3):289-93. PubMed ID: 1512464
    [Abstract] [Full Text] [Related]

  • 11. [Therapeutic effectiveness of hyperthermia and relation to glutathione concentration in the tumor tissues].
    Nakagawa S, Yoshikawa T, Boku Y, Arai M, Kondo M, Hirata I, Kokura S.
    Gan To Kagaku Ryoho; 1995 Sep 03; 22(11):1549-50. PubMed ID: 7574756
    [No Abstract] [Full Text] [Related]

  • 12. Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
    Allalunis-Turner MJ, Day RS, McKean JD, Petruk KC, Allen PB, Aronyk KE, Weir BK, Huyser-Wierenga D, Fulton DS, Urtasun RC.
    J Neurooncol; 1991 Oct 03; 11(2):157-64. PubMed ID: 1744683
    [Abstract] [Full Text] [Related]

  • 13. Cytotoxicity of antitumor platinum complexes with L-buthionine-(R,S)-sulfoximine and/or etanidazole in human carcinoma cell lines sensitive and resistant to cisplatin.
    Brooks SE, Korbut TT, Dupuis NP, Holden SA, Teicher BA.
    Cancer Chemother Pharmacol; 1995 Oct 03; 36(5):431-8. PubMed ID: 7634385
    [Abstract] [Full Text] [Related]

  • 14. Lack of enhanced antitumor efficacy for L-buthionine sulfoximine in combination with carmustine, cyclophosphamide, doxorubicin or melphalan in mice.
    Soble MJ, Dorr RT.
    Anticancer Res; 1988 Oct 03; 8(1):17-22. PubMed ID: 3358633
    [Abstract] [Full Text] [Related]

  • 15. [Use of inhibitors of glutathione and glutathione transferase for overcoming resistance of tumor to cytostatics in an in vivo system].
    Donenko FV, Sitdikova SM, Kabieva AO, Polotskiĭ BE, Machaladze ZO, Davydov MI, Moroz LV.
    Biull Eksp Biol Med; 1995 Feb 03; 119(2):212-4. PubMed ID: 7670058
    [No Abstract] [Full Text] [Related]

  • 16. Variable baseline gamma-glutamylcysteine synthetase messenger RNA expression in peripheral mononuclear cells of cancer patients, and its induction by buthionine sulfoximine treatment.
    Yao K, Godwin AK, Ozols RF, Hamilton TC, O'Dwyer PJ.
    Cancer Res; 1993 Aug 15; 53(16):3662-6. PubMed ID: 8101766
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetics of buthionine sulfoximine (NSC 326231) and its effect on melphalan-induced toxicity in mice.
    Smith AC, Liao JT, Page JG, Wientjes MG, Grieshaber CK.
    Cancer Res; 1989 Oct 01; 49(19):5385-91. PubMed ID: 2766304
    [Abstract] [Full Text] [Related]

  • 18. Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion.
    Friedman HS, Colvin OM, Griffith OW, Lippitz B, Elion GB, Schold SC, Hilton J, Bigner DD.
    J Natl Cancer Inst; 1989 Apr 05; 81(7):524-7. PubMed ID: 2921776
    [Abstract] [Full Text] [Related]

  • 19. Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.
    Ono K, Komuro C, Tsutsui K, Shibamoto Y, Nishidai T, Takahashi M, Abe M, Shrieve DC.
    Br J Cancer; 1986 Nov 05; 54(5):749-54. PubMed ID: 3801271
    [Abstract] [Full Text] [Related]

  • 20. Effect of acute and chronic glutathione depletion on renal function in the rat.
    Garber SL, Arruda JA, Dunea G.
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol; 1995 Jun 05; 111(2):237-41. PubMed ID: 8521245
    [Abstract] [Full Text] [Related]


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