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Journal Abstract Search

278 related items for PubMed ID: 17344386

  • 1. A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
    Latouche M, Lasbleiz C, Martin E, Monnier V, Debeir T, Mouatt-Prigent A, Muriel MP, Morel L, Ruberg M, Brice A, Stevanin G, Tricoire H.
    J Neurosci; 2007 Mar 07; 27(10):2483-92. PubMed ID: 17344386
    [Abstract] [Full Text] [Related]

  • 2. SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7.
    Janer A, Werner A, Takahashi-Fujigasaki J, Daret A, Fujigasaki H, Takada K, Duyckaerts C, Brice A, Dejean A, Sittler A.
    Hum Mol Genet; 2010 Jan 01; 19(1):181-95. PubMed ID: 19843541
    [Abstract] [Full Text] [Related]

  • 3. SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models.
    Marinello M, Werner A, Giannone M, Tahiri K, Alves S, Tesson C, den Dunnen W, Seeler JS, Brice A, Sittler A.
    Dis Model Mech; 2019 Jan 11; 12(1):. PubMed ID: 30559154
    [Abstract] [Full Text] [Related]

  • 4. SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types.
    Yvert G, Lindenberg KS, Devys D, Helmlinger D, Landwehrmeyer GB, Mandel JL.
    Hum Mol Genet; 2001 Aug 01; 10(16):1679-92. PubMed ID: 11487572
    [Abstract] [Full Text] [Related]

  • 5. Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes.
    McCullough SD, Xu X, Dent SY, Bekiranov S, Roeder RG, Grant PA.
    Proc Natl Acad Sci U S A; 2012 Dec 26; 109(52):21319-24. PubMed ID: 23236151
    [Abstract] [Full Text] [Related]

  • 6. Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.
    Furrer SA, Mohanachandran MS, Waldherr SM, Chang C, Damian VA, Sopher BL, Garden GA, La Spada AR.
    J Neurosci; 2011 Nov 09; 31(45):16269-78. PubMed ID: 22072678
    [Abstract] [Full Text] [Related]

  • 7. Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7.
    Furrer SA, Waldherr SM, Mohanachandran MS, Baughn TD, Nguyen KT, Sopher BL, Damian VA, Garden GA, La Spada AR.
    Hum Mol Genet; 2013 Mar 01; 22(5):890-903. PubMed ID: 23197655
    [Abstract] [Full Text] [Related]

  • 8. Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
    Zander C, Takahashi J, El Hachimi KH, Fujigasaki H, Albanese V, Lebre AS, Stevanin G, Duyckaerts C, Brice A.
    Hum Mol Genet; 2001 Oct 15; 10(22):2569-79. PubMed ID: 11709544
    [Abstract] [Full Text] [Related]

  • 9. Interferon β induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
    Chort A, Alves S, Marinello M, Dufresnois B, Dornbierer JG, Tesson C, Latouche M, Baker DP, Barkats M, El Hachimi KH, Ruberg M, Janer A, Stevanin G, Brice A, Sittler A.
    Brain; 2013 Jun 15; 136(Pt 6):1732-45. PubMed ID: 23518714
    [Abstract] [Full Text] [Related]

  • 10. Progressive degeneration in a new Drosophila model of spinocerebellar ataxia type 7.
    Sujkowski A, Ranxhi B, Bangash ZR, Chbihi ZM, Prifti MV, Qadri Z, Alam N, Todi SV, Tsou WL.
    Sci Rep; 2024 Jun 21; 14(1):14332. PubMed ID: 38906973
    [Abstract] [Full Text] [Related]

  • 11. Molecular Targets and Therapeutic Strategies in Spinocerebellar Ataxia Type 7.
    Niewiadomska-Cimicka A, Trottier Y.
    Neurotherapeutics; 2019 Oct 21; 16(4):1074-1096. PubMed ID: 31432449
    [Abstract] [Full Text] [Related]

  • 12. Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.
    Helmlinger D, Abou-Sleymane G, Yvert G, Rousseau S, Weber C, Trottier Y, Mandel JL, Devys D.
    J Neurosci; 2004 Feb 25; 24(8):1881-7. PubMed ID: 14985428
    [Abstract] [Full Text] [Related]

  • 13. Altered p53 and NOX1 activity cause bioenergetic defects in a SCA7 polyglutamine disease model.
    Ajayi A, Yu X, Wahlo-Svedin C, Tsirigotaki G, Karlström V, Ström AL.
    Biochim Biophys Acta; 2015 Feb 25; 1847(4-5):418-428. PubMed ID: 25647692
    [Abstract] [Full Text] [Related]

  • 14. Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice.
    Helmlinger D, Bonnet J, Mandel JL, Trottier Y, Devys D.
    J Biol Chem; 2004 Dec 31; 279(53):55969-77. PubMed ID: 15494410
    [Abstract] [Full Text] [Related]

  • 15. Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment.
    Mookerjee S, Papanikolaou T, Guyenet SJ, Sampath V, Lin A, Vitelli C, DeGiacomo F, Sopher BL, Chen SF, La Spada AR, Ellerby LM.
    J Neurosci; 2009 Dec 02; 29(48):15134-44. PubMed ID: 19955365
    [Abstract] [Full Text] [Related]

  • 16. Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model.
    Yu X, Ajayi A, Boga NR, Ström AL.
    J Mol Neurosci; 2012 Jun 02; 47(2):219-33. PubMed ID: 22367614
    [Abstract] [Full Text] [Related]

  • 17. Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model.
    Duncan CE, An MC, Papanikolaou T, Rugani C, Vitelli C, Ellerby LM.
    Mol Neurodegener; 2013 Oct 27; 8():42. PubMed ID: 24160175
    [Abstract] [Full Text] [Related]

  • 18. Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration.
    Garden GA, La Spada AR.
    Cerebellum; 2008 Oct 27; 7(2):138-49. PubMed ID: 18418675
    [Abstract] [Full Text] [Related]

  • 19. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.
    Alves S, Marais T, Biferi MG, Furling D, Marinello M, El Hachimi K, Cartier N, Ruberg M, Stevanin G, Brice A, Barkats M, Sittler A.
    Mol Neurodegener; 2016 Jul 28; 11(1):58. PubMed ID: 27465358
    [Abstract] [Full Text] [Related]

  • 20. Polyglutamine and polyalanine expansions in ataxin7 result in different types of aggregation and levels of toxicity.
    Latouche M, Fragner P, Martin E, El Hachimi KH, Zander C, Sittler A, Ruberg M, Brice A, Stevanin G.
    Mol Cell Neurosci; 2006 Mar 28; 31(3):438-45. PubMed ID: 16325416
    [Abstract] [Full Text] [Related]

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