These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway. Doepfner KT, Spertini O, Arcaro A. Leukemia; 2007 Sep; 21(9):1921-30. PubMed ID: 17581609 [Abstract] [Full Text] [Related]
3. Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo. Tanno B, Mancini C, Vitali R, Mancuso M, McDowell HP, Dominici C, Raschellà G. Clin Cancer Res; 2006 Nov 15; 12(22):6772-80. PubMed ID: 17121898 [Abstract] [Full Text] [Related]
8. Insulin-like growth factor receptor I targeting in epithelial ovarian cancer. Gotlieb WH, Bruchim I, Gu J, Shi Y, Camirand A, Blouin MJ, Zhao Y, Pollak MN. Gynecol Oncol; 2006 Feb 15; 100(2):389-96. PubMed ID: 16300820 [Abstract] [Full Text] [Related]
9. Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis. Moser C, Schachtschneider P, Lang SA, Gaumann A, Mori A, Zimmermann J, Schlitt HJ, Geissler EK, Stoeltzing O. Eur J Cancer; 2008 Jul 15; 44(11):1577-86. PubMed ID: 18445520 [Abstract] [Full Text] [Related]
10. Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors. Scotlandi K, Manara MC, Nicoletti G, Lollini PL, Lukas S, Benini S, Croci S, Perdichizzi S, Zambelli D, Serra M, García-Echeverría C, Hofmann F, Picci P. Cancer Res; 2005 May 01; 65(9):3868-76. PubMed ID: 15867386 [Abstract] [Full Text] [Related]
11. Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity. Bao XH, Takaoka M, Hao HF, Wang ZG, Fukazawa T, Yamatsuji T, Sakurama K, Sun DS, Nagasaka T, Fujiwara T, Naomoto Y. Anticancer Res; 2012 Jul 01; 32(7):2827-34. PubMed ID: 22753744 [Abstract] [Full Text] [Related]
12. Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001. Baumann P, Hagemeier H, Mandl-Weber S, Franke D, Schmidmaier R. Anticancer Drugs; 2009 Apr 01; 20(4):259-66. PubMed ID: 19240643 [Abstract] [Full Text] [Related]
13. Insulin-like growth factor-I receptor inhibition by specific tyrosine kinase inhibitor NVP-AEW541 in endometrioid and serous papillary endometrial cancer cell lines. Attias-Geva Z, Bentov I, Fishman A, Werner H, Bruchim I. Gynecol Oncol; 2011 May 01; 121(2):383-9. PubMed ID: 21295335 [Abstract] [Full Text] [Related]
14. The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy. Warshamana-Greene GS, Litz J, Buchdunger E, García-Echeverría C, Hofmann F, Krystal GW. Clin Cancer Res; 2005 Feb 15; 11(4):1563-71. PubMed ID: 15746061 [Abstract] [Full Text] [Related]
15. Sensitivity of breast cancer cell lines to the novel insulin-like growth factor-1 receptor (IGF-1R) inhibitor NVP-AEW541 is dependent on the level of IRS-1 expression. Mukohara T, Shimada H, Ogasawara N, Wanikawa R, Shimomura M, Nakatsura T, Ishii G, Park JO, Jänne PA, Saijo N, Minami H. Cancer Lett; 2009 Sep 08; 282(1):14-24. PubMed ID: 19345478 [Abstract] [Full Text] [Related]
16. The insulin-like growth factor-1 receptor kinase inhibitor, NVP-ADW742, suppresses survival and resistance to chemotherapy in acute myeloid leukemia cells. He Y, Zhang J, Zheng J, Du W, Xiao H, Liu W, Li X, Chen X, Yang L, Huang S. Oncol Res; 2010 Sep 08; 19(1):35-43. PubMed ID: 21141739 [Abstract] [Full Text] [Related]
17. The IGFR1 inhibitor NVP-AEW541 disrupts a pro-survival and pro-angiogenic IGF-STAT3-HIF1 pathway in human glioblastoma cells. Gariboldi MB, Ravizza R, Monti E. Biochem Pharmacol; 2010 Aug 15; 80(4):455-62. PubMed ID: 20488164 [Abstract] [Full Text] [Related]
18. Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas. Piao W, Wang Y, Adachi Y, Yamamoto H, Li R, Imsumran A, Li H, Maehata T, Ii M, Arimura Y, Lee CT, Shinomura Y, Carbone DP, Imai K. Mol Cancer Ther; 2008 Jun 15; 7(6):1483-93. PubMed ID: 18566219 [Abstract] [Full Text] [Related]
19. Repression of malignant tumor progression upon pharmacologic IGF1R blockade in a mouse model of insulinoma. Zumsteg A, Caviezel C, Pisarsky L, Strittmatter K, García-Echeverría C, Hofmann F, Christofori G. Mol Cancer Res; 2012 Jun 15; 10(6):800-9. PubMed ID: 22562956 [Abstract] [Full Text] [Related]
20. Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma. Friedrichs N, Küchler J, Endl E, Koch A, Czerwitzki J, Wurst P, Metzger D, Schulte JH, Holst MI, Heukamp LC, Larsson O, Tanaka S, Kawai A, Wardelmann E, Buettner R, Pietsch T, Hartmann W. J Pathol; 2008 Dec 15; 216(4):428-39. PubMed ID: 18855347 [Abstract] [Full Text] [Related] Page: [Next] [New Search]