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Journal Abstract Search
191 related items for PubMed ID: 17368901
1. 1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation. Wei RG, Adler M, Davey D, Ho E, Mohan R, Polokoff M, Tseng JL, Whitlow M, Xu W, Yuan S, Phillips G. Bioorg Med Chem Lett; 2007 May 01; 17(9):2499-504. PubMed ID: 17368901 [Abstract] [Full Text] [Related]
2. Discovery of a series of aminopiperidines as novel iNOS inhibitors. Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE. Bioorg Med Chem Lett; 2008 Jan 01; 18(1):336-43. PubMed ID: 18024030 [Abstract] [Full Text] [Related]
3. The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthase. Whitlow M, Adler M, Davey D, Huang Q, Koovakkat S, Parkinson JF, Pham E, Polokoff M, Xu W, Yuan S, Phillips G. Bioorg Med Chem Lett; 2007 May 01; 17(9):2505-8. PubMed ID: 17336523 [Abstract] [Full Text] [Related]
7. PPA250 [3-(2,4-difluorophenyl)-6-[2-[4-(1H-imidazol-1-ylmethyl) phenoxy]ethoxy]-2-phenylpyridine], a novel orally effective inhibitor of the dimerization of inducible nitric-oxide synthase, exhibits an anti-inflammatory effect in animal models of chronic arthritis. Ohtsuka M, Konno F, Honda H, Oikawa T, Ishikawa M, Iwase N, Isomae K, Ishii F, Hemmi H, Sato S. J Pharmacol Exp Ther; 2002 Oct 01; 303(1):52-7. PubMed ID: 12235232 [Abstract] [Full Text] [Related]
12. BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase. Tiso M, Strub A, Hesslinger C, Kenney CT, Boer R, Stuehr DJ. Mol Pharmacol; 2008 Apr 01; 73(4):1244-53. PubMed ID: 18178668 [Abstract] [Full Text] [Related]
13. KLYP956 is a non-imidazole-based orally active inhibitor of nitric-oxide synthase dimerization. Symons KT, Massari ME, Nguyen PM, Lee TT, Roppe J, Bonnefous C, Payne JE, Smith ND, Noble SA, Sablad M, Rozenkrants N, Zhang Y, Rao TS, Shiau AK, Hassig CA. Mol Pharmacol; 2009 Jul 01; 76(1):153-62. PubMed ID: 19364813 [Abstract] [Full Text] [Related]