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678 related items for PubMed ID: 17370251

  • 1. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.
    Worek F, Aurbek N, Thiermann H.
    J Appl Toxicol; 2007; 27(6):582-8. PubMed ID: 17370251
    [Abstract] [Full Text] [Related]

  • 2. Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics.
    Worek F, Koller M, Thiermann H, Wille T.
    Toxicology; 2016 Mar 28; 350-352():25-30. PubMed ID: 27153754
    [Abstract] [Full Text] [Related]

  • 3. A comparison of the potency of the oxime HLö-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinová M.
    Acta Medica (Hradec Kralove); 2005 Mar 28; 48(2):81-6. PubMed ID: 16259317
    [Abstract] [Full Text] [Related]

  • 4. Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates.
    Worek F, Reiter G, Eyer P, Szinicz L.
    Arch Toxicol; 2002 Sep 28; 76(9):523-9. PubMed ID: 12242610
    [Abstract] [Full Text] [Related]

  • 5. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study.
    Worek F, Herkert NM, Koller M, Aurbek N, Thiermann H.
    Toxicol Lett; 2009 Jun 01; 187(2):119-23. PubMed ID: 19429253
    [Abstract] [Full Text] [Related]

  • 6. Reactivating potency of obidoxime, pralidoxime, HI 6 and HLö 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds.
    Worek F, Widmann R, Knopff O, Szinicz L.
    Arch Toxicol; 1998 Mar 01; 72(4):237-43. PubMed ID: 9587020
    [Abstract] [Full Text] [Related]

  • 7. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM, Brecht KM, Sweeney RE.
    Chem Biol Interact; 2013 Mar 25; 203(1):72-6. PubMed ID: 22982773
    [Abstract] [Full Text] [Related]

  • 8. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J.
    Pharmazie; 2004 Oct 25; 59(10):795-8. PubMed ID: 15544060
    [Abstract] [Full Text] [Related]

  • 9. In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinova M.
    J Toxicol Environ Health A; 2006 Aug 25; 69(15):1431-40. PubMed ID: 16766478
    [Abstract] [Full Text] [Related]

  • 10. A structure-activity analysis of the variation in oxime efficacy against nerve agents.
    Maxwell DM, Koplovitz I, Worek F, Sweeney RE.
    Toxicol Appl Pharmacol; 2008 Sep 01; 231(2):157-64. PubMed ID: 18508103
    [Abstract] [Full Text] [Related]

  • 11. Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes.
    Kuca K, Jun D.
    J Med Toxicol; 2006 Dec 01; 2(4):141-6. PubMed ID: 18072133
    [Abstract] [Full Text] [Related]

  • 12. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N, Herkert NM, Koller M, Thiermann H, Worek F.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):215-9. PubMed ID: 20105433
    [Abstract] [Full Text] [Related]

  • 13. A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats.
    Kassa J, Jun D, Kuca K.
    J Enzyme Inhib Med Chem; 2007 Jun 06; 22(3):297-300. PubMed ID: 17674811
    [Abstract] [Full Text] [Related]

  • 14. Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6.
    Wille T, von der Wellen J, Thiermann H, Worek F.
    Arch Toxicol; 2017 Mar 06; 91(3):1309-1318. PubMed ID: 27358236
    [Abstract] [Full Text] [Related]

  • 15. Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.
    Worek F, von der Wellen J, Musilek K, Kuca K, Thiermann H.
    Arch Toxicol; 2012 Sep 06; 86(9):1379-86. PubMed ID: 22437842
    [Abstract] [Full Text] [Related]

  • 16. In vitro reactivation of acetylcholinesterase using the oxime K027.
    Kuca K, Kassa J.
    Vet Hum Toxicol; 2004 Feb 06; 46(1):15-8. PubMed ID: 14748409
    [Abstract] [Full Text] [Related]

  • 17. Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
    Kuca K, Jun D, Bajgar J.
    Drug Chem Toxicol; 2007 Feb 06; 30(1):31-40. PubMed ID: 17364862
    [Abstract] [Full Text] [Related]

  • 18. Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.
    Sahu AK, Sharma R, Gupta B, Musilek K, Kuca K, Acharya J, Ghosh KK.
    Toxicol Mech Methods; 2016 Jun 06; 26(5):319-26. PubMed ID: 27101948
    [Abstract] [Full Text] [Related]

  • 19. A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques.
    Bajgar J, Hajek P, Zdarova JK, Kassa J, Paseka A, Slizova D, Krs O, Kuca K, Jun D, Fusek J, Capek L.
    J Enzyme Inhib Med Chem; 2010 Dec 06; 25(6):790-7. PubMed ID: 21054236
    [Abstract] [Full Text] [Related]

  • 20. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase.
    Bartling A, Worek F, Szinicz L, Thiermann H.
    Toxicology; 2007 Apr 20; 233(1-3):166-72. PubMed ID: 16904809
    [Abstract] [Full Text] [Related]

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