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Journal Abstract Search

136 related items for PubMed ID: 17372273

  • 1. EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes.
    Grandal MV, Zandi R, Pedersen MW, Willumsen BM, van Deurs B, Poulsen HS.
    Carcinogenesis; 2007 Jul; 28(7):1408-17. PubMed ID: 17372273
    [Abstract] [Full Text] [Related]

  • 2. A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.
    Waterman H, Katz M, Rubin C, Shtiegman K, Lavi S, Elson A, Jovin T, Yarden Y.
    EMBO J; 2002 Feb 01; 21(3):303-13. PubMed ID: 11823423
    [Abstract] [Full Text] [Related]

  • 3. Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
    Duan L, Miura Y, Dimri M, Majumder B, Dodge IL, Reddi AL, Ghosh A, Fernandes N, Zhou P, Mullane-Robinson K, Rao N, Donoghue S, Rogers RA, Bowtell D, Naramura M, Gu H, Band V, Band H.
    J Biol Chem; 2003 Aug 01; 278(31):28950-60. PubMed ID: 12754251
    [Abstract] [Full Text] [Related]

  • 4. Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation.
    Grøvdal LM, Stang E, Sorkin A, Madshus IH.
    Exp Cell Res; 2004 Nov 01; 300(2):388-95. PubMed ID: 15475003
    [Abstract] [Full Text] [Related]

  • 5. Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized.
    Padrón D, Sato M, Shay JW, Gazdar AF, Minna JD, Roth MG.
    Cancer Res; 2007 Aug 15; 67(16):7695-702. PubMed ID: 17699773
    [Abstract] [Full Text] [Related]

  • 6. Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.
    Shtiegman K, Kochupurakkal BS, Zwang Y, Pines G, Starr A, Vexler A, Citri A, Katz M, Lavi S, Ben-Basat Y, Benjamin S, Corso S, Gan J, Yosef RB, Giordano S, Yarden Y.
    Oncogene; 2007 Oct 25; 26(49):6968-78. PubMed ID: 17486068
    [Abstract] [Full Text] [Related]

  • 7. Abi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosis.
    Tanos BE, Pendergast AM.
    Cell Signal; 2007 Jul 25; 19(7):1602-9. PubMed ID: 17395426
    [Abstract] [Full Text] [Related]

  • 8. Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF.
    Oksvold MP, Skarpen E, Wierød L, Paulsen RE, Huitfeldt HS.
    Eur J Cell Biol; 2001 Apr 25; 80(4):285-94. PubMed ID: 11370743
    [Abstract] [Full Text] [Related]

  • 9. Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl.
    Sun J, Pedersen M, Bengtsson S, Rönnstrand L.
    Exp Cell Res; 2007 Nov 01; 313(18):3935-42. PubMed ID: 17904548
    [Abstract] [Full Text] [Related]

  • 10. Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor.
    Timpson P, Lynch DK, Schramek D, Walker F, Daly RJ.
    Cancer Res; 2005 Apr 15; 65(8):3273-80. PubMed ID: 15833860
    [Abstract] [Full Text] [Related]

  • 11. Monoclonal antibody cetuximab binds to and down-regulates constitutively activated epidermal growth factor receptor vIII on the cell surface.
    Patel D, Lahiji A, Patel S, Franklin M, Jimenez X, Hicklin DJ, Kang X.
    Anticancer Res; 2007 Apr 15; 27(5A):3355-66. PubMed ID: 17970081
    [Abstract] [Full Text] [Related]

  • 12. [Ubiquitination-mediated degradation of epidermal growth factor receptor].
    Xiu X, Lü ZM.
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2005 Feb 15; 27(1):120-7. PubMed ID: 15782507
    [Abstract] [Full Text] [Related]

  • 13. Endocytosis and intracellular trafficking of ErbBs.
    Sorkin A, Goh LK.
    Exp Cell Res; 2008 Oct 15; 314(17):3093-106. PubMed ID: 18793634
    [Abstract] [Full Text] [Related]

  • 14. EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line.
    Nishimura Y, Takiguchi S, Ito S, Itoh K.
    Int J Oncol; 2015 Apr 15; 46(4):1721-9. PubMed ID: 25653196
    [Abstract] [Full Text] [Related]

  • 15. EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins.
    Davies GC, Ryan PE, Rahman L, Zajac-Kaye M, Lipkowitz S.
    Oncogene; 2006 Oct 19; 25(49):6497-509. PubMed ID: 16702950
    [Abstract] [Full Text] [Related]

  • 16. Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis.
    Furukawa M, Nagatomo I, Kumagai T, Yamadori T, Takahashi R, Yoshimura M, Yoneda T, Takeda Y, Goya S, Matsuoka H, Kijima T, Yoshida M, Osaki T, Tachibana I, Greene MI, Kawase I.
    DNA Cell Biol; 2007 Mar 19; 26(3):178-85. PubMed ID: 17417946
    [Abstract] [Full Text] [Related]

  • 17. Endocytosis and intracellular trafficking of ErbBs.
    Sorkin A, Goh LK.
    Exp Cell Res; 2009 Feb 15; 315(4):683-96. PubMed ID: 19278030
    [Abstract] [Full Text] [Related]

  • 18. Epidermal growth factor receptor degradation: an alternative view of oncogenic pathways.
    Kirisits A, Pils D, Krainer M.
    Int J Biochem Cell Biol; 2007 Feb 15; 39(12):2173-82. PubMed ID: 17855153
    [Abstract] [Full Text] [Related]

  • 19. Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.
    Martin NP, Mohney RP, Dunn S, Das M, Scappini E, O'Bryan JP.
    Mol Pharmacol; 2006 Nov 15; 70(5):1643-53. PubMed ID: 16914641
    [Abstract] [Full Text] [Related]

  • 20. CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins.
    Wang Y, Yeung YG, Stanley ER.
    J Cell Biochem; 1999 Jan 01; 72(1):119-34. PubMed ID: 10025673
    [Abstract] [Full Text] [Related]

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