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Journal Abstract Search

169 related items for PubMed ID: 1737372

  • 1. Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitor.
    O'Connor BM, Jackman AL, Crossley PH, Freemantle SE, Lunec J, Calvert AH.
    Cancer Res; 1992 Mar 01; 52(5):1137-43. PubMed ID: 1737372
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  • 2. Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo.
    Jackman AL, Taylor GA, O'Connor BM, Bishop JA, Moran RG, Calvert AH.
    Cancer Res; 1990 Sep 01; 50(17):5212-8. PubMed ID: 2386929
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  • 3. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
    Jackman AL, Alison DL, Calvert AH, Harrap KR.
    Cancer Res; 1986 Jun 01; 46(6):2810-5. PubMed ID: 2938731
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  • 4. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH.
    Cancer Res; 1992 Apr 15; 52(8):2148-55. PubMed ID: 1313737
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  • 8. Cellular pharmacology and in vivo activity of a new anticancer agent, ZD9331: a water-soluble, nonpolyglutamatable, quinazoline-based inhibitor of thymidylate synthase.
    Jackman AL, Kimbell R, Aherne GW, Brunton L, Jansen G, Stephens TC, Smith MN, Wardleworth JM, Boyle FT.
    Clin Cancer Res; 1997 Jun 15; 3(6):911-21. PubMed ID: 9815766
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  • 10. The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).
    Jackman AL, Newell DR, Gibson W, Jodrell DI, Taylor GA, Bishop JA, Hughes LR, Calvert AH.
    Biochem Pharmacol; 1991 Oct 24; 42(10):1885-95. PubMed ID: 1741766
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  • 11. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
    Jansen G, Schornagel JH, Westerhof GR, Rijksen G, Newell DR, Jackman AL.
    Cancer Res; 1990 Dec 01; 50(23):7544-8. PubMed ID: 2253202
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  • 13. Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions.
    Peters GJ, Smitskamp-Wilms E, Smid K, Pinedo HM, Jansen G.
    Cancer Res; 1999 Nov 01; 59(21):5529-35. PubMed ID: 10554030
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  • 14. Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
    Mauritz R, Bekkenk MW, Rots MG, Pieters R, Mini E, van Zantwijk CH, Veerman AJ, Peters GJ, Jansen G.
    Clin Cancer Res; 1998 Oct 01; 4(10):2399-410. PubMed ID: 9796971
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