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526 related items for PubMed ID: 17376561

  • 1. Potent and selective agonists of alpha-melanotropin (alphaMSH) action at human melanocortin receptor 5; linear analogs of alpha-melanotropin.
    Bednarek MA, MacNeil T, Tang R, Fong TM, Cabello MA, Maroto M, Teran A.
    Peptides; 2007 May; 28(5):1020-8. PubMed ID: 17376561
    [Abstract] [Full Text] [Related]

  • 2. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
    Haskell-Luevano C, Nikiforovich G, Sharma SD, Yang YK, Dickinson C, Hruby VJ, Gantz I.
    J Med Chem; 1997 May 23; 40(11):1738-48. PubMed ID: 9171884
    [Abstract] [Full Text] [Related]

  • 3. Potent and selective agonists of human melanocortin receptor 5: cyclic analogues of alpha-melanocyte-stimulating hormone.
    Bednarek MA, MacNeil T, Tang R, Fong TM, Cabello MA, Maroto M, Teran A.
    J Med Chem; 2007 May 17; 50(10):2520-6. PubMed ID: 17455928
    [Abstract] [Full Text] [Related]

  • 4. Analogs of alpha-melanocyte stimulating hormone with high agonist potency and selectivity at human melanocortin receptor 1b: the role of Trp(9) in molecular recognition.
    Bednarek MA, Macneil T, Tang R, Fong TM, Angeles Cabello M, Maroto M, Teran A.
    Biopolymers; 2008 May 17; 89(5):401-8. PubMed ID: 17926329
    [Abstract] [Full Text] [Related]

  • 5. Potent and selective peptide agonists of alpha-melanocyte stimulating hormone (alphaMSH) action at human melanocortin receptor 5; their synthesis and biological evaluation in vitro.
    Bednarek MA, MacNeil T, Tang R, Fong TM, Angeles Cabello M, Maroto M, Teran A.
    Chem Biol Drug Des; 2007 May 17; 69(5):350-5. PubMed ID: 17539827
    [Abstract] [Full Text] [Related]

  • 6. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.
    Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ.
    J Med Chem; 2003 Aug 14; 46(17):3728-33. PubMed ID: 12904077
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.
    Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ.
    J Med Chem; 2003 Nov 06; 46(23):4965-73. PubMed ID: 14584947
    [Abstract] [Full Text] [Related]

  • 8. Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro.
    Bednarek MA, MacNeil T, Tang R, Kalyani RN, Van der Ploeg LH, Weinberg DH.
    Biochem Biophys Res Commun; 2001 Aug 24; 286(3):641-5. PubMed ID: 11511108
    [Abstract] [Full Text] [Related]

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  • 10. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
    Han G, Haskell-Luevano C, Kendall L, Bonner G, Hadley ME, Cone RD, Hruby VJ.
    J Med Chem; 2004 Mar 11; 47(6):1514-26. PubMed ID: 14998337
    [Abstract] [Full Text] [Related]

  • 11. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C, Hendrata S, North C, Sawyer TK, Hadley ME, Hruby VJ, Dickinson C, Gantz I.
    J Med Chem; 1997 Jul 04; 40(14):2133-9. PubMed ID: 9216831
    [Abstract] [Full Text] [Related]

  • 12. Cyclic analogs of alpha-melanocyte-stimulating hormone (alphaMSH) with high agonist potency and selectivity at human melanocortin receptor 1b.
    Bednarek MA, MacNeil T, Tang R, Fong TM, Cabello MA, Maroto M, Teran A.
    Peptides; 2008 Jun 04; 29(6):1010-7. PubMed ID: 18378043
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of highly potent and selective melanotropin analogues of SHU9119 modified at position 6.
    Grieco P, Han G, Weinberg D, Van der Ploeg LH, Hruby VJ.
    Biochem Biophys Res Commun; 2002 Apr 12; 292(4):1075-80. PubMed ID: 11944925
    [Abstract] [Full Text] [Related]

  • 14. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist.
    Han G, Quillan JM, Carlson K, Sadée W, Hruby VJ.
    J Med Chem; 2003 Feb 27; 46(5):810-9. PubMed ID: 12593660
    [Abstract] [Full Text] [Related]

  • 15. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA, Doufexis M, Kapas S, Chhajlani V.
    Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737
    [Abstract] [Full Text] [Related]

  • 16. Analogs of MTII, lactam derivatives of alpha-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5.
    Bednarek MA, Macneil T, Kalyani RN, Tang R, Van der Ploeg LH, Weinberg DH.
    Biochem Biophys Res Commun; 1999 Jul 22; 261(1):209-13. PubMed ID: 10405347
    [Abstract] [Full Text] [Related]

  • 17. Aza-scanning of the potent melanocortin receptor agonist Ac-His-D-Phe-Arg-Trp-NH.
    Boeglin D, Xiang Z, Sorenson NB, Wood MS, Haskell-Luevano C, Lubell WD.
    Chem Biol Drug Des; 2006 Apr 22; 67(4):275-83. PubMed ID: 16629825
    [Abstract] [Full Text] [Related]

  • 18. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A, Wang XS, Joseph CG, Xiang Z, Bauzo RM, Scott JW, Sorensen NB, Shaw AM, Millard WJ, Richards NG, Haskell-Luevano C.
    J Med Chem; 2004 Apr 22; 47(9):2194-207. PubMed ID: 15084118
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