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115 related items for PubMed ID: 1737769

  • 1. Formation of a free acyl adenylate during the activation of 2-propylpentanoic acid. Valproyl-AMP: a novel cellular metabolite of valproic acid.
    Mao LF, Millington DS, Schulz H.
    J Biol Chem; 1992 Feb 15; 267(5):3143-6. PubMed ID: 1737769
    [Abstract] [Full Text] [Related]

  • 2. Valproyl-dephosphoCoA: a novel metabolite of valproate formed in vitro in rat liver mitochondria.
    Silva MF, Ijlst L, Allers P, Jakobs C, Duran M, de Almeida IT, Wanders RJ.
    Drug Metab Dispos; 2004 Nov 15; 32(11):1304-10. PubMed ID: 15483197
    [Abstract] [Full Text] [Related]

  • 3. The enzymatic basis for the metabolism and inhibitory effects of valproic acid: dehydrogenation of valproyl-CoA by 2-methyl-branched-chain acyl-CoA dehydrogenase.
    Ito M, Ikeda Y, Arnez JG, Finocchiaro G, Tanaka K.
    Biochim Biophys Acta; 1990 May 16; 1034(2):213-8. PubMed ID: 2112956
    [Abstract] [Full Text] [Related]

  • 4. Studies on the extra-mitochondrial CoA -ester formation of valproic and Delta4 -valproic acids.
    Aires CC, Ruiter JP, Luís PB, ten Brink HJ, Ijlst L, de Almeida IT, Duran M, Wanders RJ, Silva MF.
    Biochim Biophys Acta; 2007 Apr 16; 1771(4):533-43. PubMed ID: 17321204
    [Abstract] [Full Text] [Related]

  • 5. Influence of valproic acid on hepatic carbohydrate and lipid metabolism.
    Becker CM, Harris RA.
    Arch Biochem Biophys; 1983 Jun 16; 223(2):381-92. PubMed ID: 6407400
    [Abstract] [Full Text] [Related]

  • 6. Mitochondrial metabolism of valproic acid.
    Li J, Norwood DL, Mao LF, Schulz H.
    Biochemistry; 1991 Jan 15; 30(2):388-94. PubMed ID: 1988037
    [Abstract] [Full Text] [Related]

  • 7. Complete beta-oxidation of valproate: cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase.
    Silva MF, Ruiter JP, Overmars H, Bootsma AH, van Gennip AH, Jakobs C, Duran M, Tavares de Almeida I, Wanders RJ.
    Biochem J; 2002 Mar 15; 362(Pt 3):755-60. PubMed ID: 11879205
    [Abstract] [Full Text] [Related]

  • 8. CoA esters of valproic acid and related metabolites are oxidized in peroxisomes through a pathway distinct from peroxisomal fatty and bile acyl-CoA beta-oxidation.
    Vamecq J, Vallee L, Fontaine M, Lambert D, Poupaert J, Nuyts JP.
    FEBS Lett; 1993 May 10; 322(2):95-100. PubMed ID: 8482393
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites.
    Silva MF, Ruiter JP, IJlst L, Allers P, ten Brink HJ, Jakobs C, Duran M, Tavares de Almeida I, Wanders RJ.
    Anal Biochem; 2001 Mar 01; 290(1):60-7. PubMed ID: 11180937
    [Abstract] [Full Text] [Related]

  • 10. Valproyl-CoA and esterified valproic acid are not found in brains of rats treated with valproic acid, but the brain concentrations of CoA and acetyl-CoA are altered.
    Deutsch J, Rapoport SI, Rosenberger TA.
    Neurochem Res; 2003 Jun 01; 28(6):861-6. PubMed ID: 12718439
    [Abstract] [Full Text] [Related]

  • 11. Effect of alpha-fluorination of valproic acid on valproyl-S-acyl-CoA formation in vivo in rats.
    Grillo MP, Chiellini G, Tonelli M, Benet LZ.
    Drug Metab Dispos; 2001 Sep 01; 29(9):1210-5. PubMed ID: 11502730
    [Abstract] [Full Text] [Related]

  • 12. Valproyl CoA: an active metabolite of valproate?
    Friel P.
    Med Hypotheses; 1990 Jan 01; 31(1):31-2. PubMed ID: 2156136
    [Abstract] [Full Text] [Related]

  • 13. Quantitation of the effect of L-carnitine on the levels of acid-soluble short-chain acyl-CoA and CoASH in rat heart and liver mitochondria.
    Lysiak W, Lilly K, DiLisa F, Toth PP, Bieber LL.
    J Biol Chem; 1988 Jan 25; 263(3):1151-6. PubMed ID: 3335535
    [Abstract] [Full Text] [Related]

  • 14. Characterization of the acyl-adenylate linked metabolite of mefenamic Acid.
    Horng H, Benet LZ.
    Chem Res Toxicol; 2013 Mar 18; 26(3):465-76. PubMed ID: 23402341
    [Abstract] [Full Text] [Related]

  • 15. Role of isovaleryl-CoA dehydrogenase and short branched-chain acyl-CoA dehydrogenase in the metabolism of valproic acid: implications for the branched-chain amino acid oxidation pathway.
    Luís PB, Ruiter JP, Ijlst L, Tavares de Almeida I, Duran M, Mohsen AW, Vockley J, Wanders RJ, Silva MF.
    Drug Metab Dispos; 2011 Jul 18; 39(7):1155-60. PubMed ID: 21430231
    [Abstract] [Full Text] [Related]

  • 16. Hepatic hydrolysis of octanoyl-CoA and valproyl-CoA in control and valproate-fed animals.
    Moore KH, Decker BP, Schreefel FP.
    Int J Biochem; 1988 Jul 18; 20(2):175-8. PubMed ID: 2895026
    [Abstract] [Full Text] [Related]

  • 17. A rapid and sensitive assay to quantify valproyl 1-O-acyl glucuronide in supernatants of sandwich-cultured rat hepatocytes using ultra-high performance liquid chromatography-tandem mass spectrometry.
    Surendradoss J, Szeitz A, Teng XW, Chang TK, Abbott FS.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Aug 01; 932():40-9. PubMed ID: 23827518
    [Abstract] [Full Text] [Related]

  • 18. Influence of valproic acid on the expression of various acyl-CoA dehydrogenases in rats.
    Kibayashi M, Nagao M, Chiba S.
    Pediatr Int; 1999 Feb 01; 41(1):52-60. PubMed ID: 10200137
    [Abstract] [Full Text] [Related]

  • 19. A single therapeutic dose of valproate affects liver carbohydrate, fat, adenylate, amino acid, coenzyme A, and carnitine metabolism in infant mice: possible clinical significance.
    Thurston JH, Carroll JE, Hauhart RE, Schiro JA.
    Life Sci; 1985 Apr 29; 36(17):1643-51. PubMed ID: 3921791
    [Abstract] [Full Text] [Related]

  • 20. The relationship between mitochondrial activation and toxicity of some substituted carboxylic acids.
    Yao KW, Mao LF, Luo MJ, Schulz H.
    Chem Biol Interact; 1994 Mar 29; 90(3):225-34. PubMed ID: 8168171
    [Abstract] [Full Text] [Related]

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