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1116 related items for PubMed ID: 17379095

  • 1. Constitutive activation of Flt3 and STAT5A enhances self-renewal and alters differentiation of hematopoietic stem cells.
    Moore MA, Dorn DC, Schuringa JJ, Chung KY, Morrone G.
    Exp Hematol; 2007 Apr; 35(4 Suppl 1):105-16. PubMed ID: 17379095
    [Abstract] [Full Text] [Related]

  • 2. FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells.
    Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D.
    Br J Haematol; 2007 Apr; 137(1):64-75. PubMed ID: 17359372
    [Abstract] [Full Text] [Related]

  • 3. Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells.
    Spiekermann K, Bagrintseva K, Schwab R, Schmieja K, Hiddemann W.
    Clin Cancer Res; 2003 Jun; 9(6):2140-50. PubMed ID: 12796379
    [Abstract] [Full Text] [Related]

  • 4. [Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms].
    Müller-Tidow C, Steur C, Mizuki M, Schwäble J, Brandts C, Berdel WE, Serve H.
    Dtsch Med Wochenschr; 2002 Oct 18; 127(42):2195-200. PubMed ID: 12397548
    [Abstract] [Full Text] [Related]

  • 5. NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells.
    Takeda A, Goolsby C, Yaseen NR.
    Cancer Res; 2006 Jul 01; 66(13):6628-37. PubMed ID: 16818636
    [Abstract] [Full Text] [Related]

  • 6. N-ras oncogene-induced gene expression in human hematopoietic progenitor cells: upregulation of p16INK4a and p21CIP1/WAF1 correlates with myeloid differentiation.
    Shen S, Passioura T, Symonds G, Dolnikov A.
    Exp Hematol; 2007 Jun 01; 35(6):908-19. PubMed ID: 17533045
    [Abstract] [Full Text] [Related]

  • 7. Aberrant expression of CD7 in myeloblasts is highly associated with de novo acute myeloid leukemias with FLT3/ITD mutation.
    Rausei-Mills V, Chang KL, Gaal KK, Weiss LM, Huang Q.
    Am J Clin Pathol; 2008 Apr 01; 129(4):624-9. PubMed ID: 18343790
    [Abstract] [Full Text] [Related]

  • 8. Enforced activation of STAT5A facilitates the generation of embryonic stem-derived hematopoietic stem cells that contribute to hematopoiesis in vivo.
    Schuringa JJ, Wu K, Morrone G, Moore MA.
    Stem Cells; 2004 Apr 01; 22(7):1191-204. PubMed ID: 15579639
    [Abstract] [Full Text] [Related]

  • 9. Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes.
    Palmqvist L, Pineault N, Wasslavik C, Humphries RK.
    PLoS One; 2007 Aug 22; 2(8):e768. PubMed ID: 17712416
    [Abstract] [Full Text] [Related]

  • 10. Stromal niche cells protect early leukemic FLT3-ITD+ progenitor cells against first-generation FLT3 tyrosine kinase inhibitors.
    Parmar A, Marz S, Rushton S, Holzwarth C, Lind K, Kayser S, Döhner K, Peschel C, Oostendorp RA, Götze KS.
    Cancer Res; 2011 Jul 01; 71(13):4696-706. PubMed ID: 21546568
    [Abstract] [Full Text] [Related]

  • 11. FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression.
    Jin G, Matsushita H, Asai S, Tsukamoto H, Ono R, Nosaka T, Yahata T, Takahashi S, Miyachi H.
    Biochem Biophys Res Commun; 2009 Dec 18; 390(3):1001-6. PubMed ID: 19853583
    [Abstract] [Full Text] [Related]

  • 12. FLT3-ITD expression levels and their effect on STAT5 in AML with and without NPM mutations.
    Seedhouse CH, Pallis M, Grundy M, Shang S, Russell NH.
    Br J Haematol; 2009 Dec 18; 147(5):653-61. PubMed ID: 19775300
    [Abstract] [Full Text] [Related]

  • 13. A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival.
    Masson K, Liu T, Khan R, Sun J, Rönnstrand L.
    Br J Haematol; 2009 Jul 18; 146(2):193-202. PubMed ID: 19438505
    [Abstract] [Full Text] [Related]

  • 14. Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 and Ezrin in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 receptors.
    Habif G, Grasset MF, Kieffer-Jaquinod S, Kuhn L, Mouchiroud G, Gobert-Gosse S.
    J Proteomics; 2013 Jan 14; 78():231-44. PubMed ID: 23017497
    [Abstract] [Full Text] [Related]

  • 15. HLA-DR-negative AML (M1 and M2): FLT3 mutations (ITD and D835) and cell-surface antigen expression.
    Syampurnawati M, Tatsumi E, Furuta K, Takenokuchi M, Nakamachi Y, Kawano S, Kumagai S, Saigo K, Matsui T, Takahashi T, Nagai K, Yabe H, Kondo S, Hayashi Y.
    Leuk Res; 2007 Jul 14; 31(7):921-9. PubMed ID: 17056111
    [Abstract] [Full Text] [Related]

  • 16. Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.
    Okamoto M, Hayakawa F, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T.
    Leukemia; 2007 Mar 14; 21(3):403-10. PubMed ID: 17230226
    [Abstract] [Full Text] [Related]

  • 17. Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis.
    Kato Y, Iwama A, Tadokoro Y, Shimoda K, Minoguchi M, Akira S, Tanaka M, Miyajima A, Kitamura T, Nakauchi H.
    J Exp Med; 2005 Jul 04; 202(1):169-79. PubMed ID: 15998795
    [Abstract] [Full Text] [Related]

  • 18. Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations.
    Harada Y, Harada H.
    J Cell Physiol; 2009 Jul 04; 220(1):16-20. PubMed ID: 19334039
    [Abstract] [Full Text] [Related]

  • 19. MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.
    Nishioka C, Ikezoe T, Yang J, Takeuchi S, Koeffler HP, Yokoyama A.
    Leuk Res; 2008 Sep 04; 32(9):1382-92. PubMed ID: 18394702
    [Abstract] [Full Text] [Related]

  • 20. Ex vivo assays to study self-renewal and long-term expansion of genetically modified primary human acute myeloid leukemia stem cells.
    Schuringa JJ, Schepers H.
    Methods Mol Biol; 2009 Sep 04; 538():287-300. PubMed ID: 19277587
    [Abstract] [Full Text] [Related]

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