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1275 related items for PubMed ID: 17379095

  • 21. MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.
    Nishioka C, Ikezoe T, Yang J, Takeuchi S, Koeffler HP, Yokoyama A.
    Leuk Res; 2008 Sep; 32(9):1382-92. PubMed ID: 18394702
    [Abstract] [Full Text] [Related]

  • 22. Ex vivo assays to study self-renewal and long-term expansion of genetically modified primary human acute myeloid leukemia stem cells.
    Schuringa JJ, Schepers H.
    Methods Mol Biol; 2009 Sep; 538():287-300. PubMed ID: 19277587
    [Abstract] [Full Text] [Related]

  • 23. Expression of pSTAT5 predicts FLT3 internal tandem duplications in acute myeloid leukemia.
    Obermann EC, Arber C, Jotterand M, Tichelli A, Hirschmann P, Tzankov A.
    Ann Hematol; 2010 Jul; 89(7):663-9. PubMed ID: 20066533
    [Abstract] [Full Text] [Related]

  • 24. Inhibition of Flt3-activating mutations does not prevent constitutive activation of ERK/Akt/STAT pathways in some AML cells: a possible cause for the limited effectiveness of monotherapy with small-molecule inhibitors.
    Siendones E, Barbarroja N, Torres LA, Buendía P, Velasco F, Dorado G, Torres A, López-Pedrera C.
    Hematol Oncol; 2007 Mar; 25(1):30-7. PubMed ID: 17128418
    [Abstract] [Full Text] [Related]

  • 25. Enforced expression of an Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesis.
    Chung KY, Morrone G, Schuringa JJ, Wong B, Dorn DC, Moore MA.
    Blood; 2005 Jan 01; 105(1):77-84. PubMed ID: 15242879
    [Abstract] [Full Text] [Related]

  • 26. Microarray and serial analysis of gene expression analyses identify known and novel transcripts overexpressed in hematopoietic stem cells.
    Georgantas RW, Tanadve V, Malehorn M, Heimfeld S, Chen C, Carr L, Martinez-Murillo F, Riggins G, Kowalski J, Civin CI.
    Cancer Res; 2004 Jul 01; 64(13):4434-41. PubMed ID: 15231652
    [Abstract] [Full Text] [Related]

  • 27. Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways.
    Dobbin E, Graham C, Corrigan PM, Thomas KG, Freeburn RW, Wheadon H.
    Exp Hematol; 2009 Jan 01; 37(1):111-121. PubMed ID: 19100521
    [Abstract] [Full Text] [Related]

  • 28. Different clinical importance of FLT3 internal tandem duplications in AML according to FAB classification: possible existence of distinct leukemogenesis involving monocyte differentiation pathway.
    Koh Y, Park J, Ahn KS, Kim I, Bang SM, Lee JH, Yoon SS, Soon Lee D, Yiul Lee Y, Park S, Kim BK.
    Ann Hematol; 2009 Nov 01; 88(11):1089-97. PubMed ID: 19296110
    [Abstract] [Full Text] [Related]

  • 29. Distinctive expression of myelomonocytic markers and down-regulation of CD34 in acute myelogenous leukaemia with FLT3 tandem duplication and nucleophosmin mutation.
    Mori Y, Yoshimoto G, Kumano T, Miyamoto T, Iino T, Takenaka K, Iwasaki H, Harada N, Kinukawa N, Nagafuji K, Teshima T, Shimoda K, Akashi K, Harada M.
    Eur J Haematol; 2007 Jul 01; 79(1):17-24. PubMed ID: 17598835
    [Abstract] [Full Text] [Related]

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  • 33. Impact of CXCR4 inhibition on FLT3-ITD-positive human AML blasts.
    Jacobi A, Thieme S, Lehmann R, Ugarte F, Malech HL, Koch S, Thiede C, Müller K, Bornhäuser M, Ryser M, Brenner S.
    Exp Hematol; 2010 Mar 01; 38(3):180-90. PubMed ID: 20035824
    [Abstract] [Full Text] [Related]

  • 34. FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation.
    Yoshimoto G, Miyamoto T, Jabbarzadeh-Tabrizi S, Iino T, Rocnik JL, Kikushige Y, Mori Y, Shima T, Iwasaki H, Takenaka K, Nagafuji K, Mizuno S, Niiro H, Gilliland GD, Akashi K.
    Blood; 2009 Dec 03; 114(24):5034-43. PubMed ID: 19808698
    [Abstract] [Full Text] [Related]

  • 35. Human CD34(+) and CD34(+)CD38(-) hematopoietic progenitors in sickle cell disease differ phenotypically and functionally from normal and suggest distinct subpopulations that generate F cells.
    Luck L, Zeng L, Hiti AL, Weinberg KI, Malik P.
    Exp Hematol; 2004 May 03; 32(5):483-93. PubMed ID: 15145217
    [Abstract] [Full Text] [Related]

  • 36. Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities.
    Costello RT, Mallet F, Gaugler B, Sainty D, Arnoulet C, Gastaut JA, Olive D.
    Cancer Res; 2000 Aug 15; 60(16):4403-11. PubMed ID: 10969785
    [Abstract] [Full Text] [Related]

  • 37. Functional alterations of Lin-CD34+CD38+ cells in chronic myelomonocytic leukemia and on progression to acute leukemia.
    Sun Q, So CC, Yip SF, Wan TS, Ma SK, Chan LC.
    Leuk Res; 2008 Sep 15; 32(9):1374-81. PubMed ID: 18372040
    [Abstract] [Full Text] [Related]

  • 38. Prognostic significance and detection of the internal tandem duplication of the FLT3 gene in acute myeloid leukemia.
    Gagyi E, Horváth E, Bödör C, Timár B, Matolcsy A, Pávai Z.
    Rom J Morphol Embryol; 2006 Sep 15; 47(4):331-7. PubMed ID: 17392978
    [Abstract] [Full Text] [Related]

  • 39. Activation of stem-cell specific genes by HOXA9 and HOXA10 homeodomain proteins in CD34+ human cord blood cells.
    Ferrell CM, Dorsam ST, Ohta H, Humphries RK, Derynck MK, Haqq C, Largman C, Lawrence HJ.
    Stem Cells; 2005 May 15; 23(5):644-55. PubMed ID: 15849172
    [Abstract] [Full Text] [Related]

  • 40. Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype.
    Neben K, Schnittger S, Brors B, Tews B, Kokocinski F, Haferlach T, Müller J, Hahn M, Hiddemann W, Eils R, Lichter P, Schoch C.
    Oncogene; 2005 Feb 24; 24(9):1580-8. PubMed ID: 15674343
    [Abstract] [Full Text] [Related]


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