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238 related items for PubMed ID: 17384440

  • 1. Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase.
    Liu HY, Collins QF, Xiong Y, Moukdar F, Lupo EG, Liu Z, Cao W.
    J Biol Chem; 2007 May 11; 282(19):14205-12. PubMed ID: 17384440
    [Abstract] [Full Text] [Related]

  • 2. Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes.
    Gonzalez-Rodriguez A, Clampit JE, Escribano O, Benito M, Rondinone CM, Valverde AM.
    Endocrinology; 2007 Feb 11; 148(2):594-608. PubMed ID: 17068137
    [Abstract] [Full Text] [Related]

  • 3. Amino Acids Attenuate Insulin Action on Gluconeogenesis and Promote Fatty Acid Biosynthesis via mTORC1 Signaling Pathway in trout Hepatocytes.
    Dai W, Panserat S, Plagnes-Juan E, Seiliez I, Skiba-Cassy S.
    Cell Physiol Biochem; 2015 Feb 11; 36(3):1084-100. PubMed ID: 26112996
    [Abstract] [Full Text] [Related]

  • 4. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
    Liu TY, Shi CX, Gao R, Sun HJ, Xiong XQ, Ding L, Chen Q, Li YH, Wang JJ, Kang YM, Zhu GQ.
    Clin Sci (Lond); 2015 Nov 11; 129(10):839-50. PubMed ID: 26201094
    [Abstract] [Full Text] [Related]

  • 5. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes.
    Valverde AM, Burks DJ, Fabregat I, Fisher TL, Carretero J, White MF, Benito M.
    Diabetes; 2003 Sep 11; 52(9):2239-48. PubMed ID: 12941762
    [Abstract] [Full Text] [Related]

  • 6. Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway.
    Li G, Barrett EJ, Barrett MO, Cao W, Liu Z.
    Endocrinology; 2007 Jul 11; 148(7):3356-63. PubMed ID: 17446186
    [Abstract] [Full Text] [Related]

  • 7. Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells.
    Shen YH, Zhang L, Gan Y, Wang X, Wang J, LeMaire SA, Coselli JS, Wang XL.
    J Biol Chem; 2006 Mar 24; 281(12):7727-36. PubMed ID: 16418168
    [Abstract] [Full Text] [Related]

  • 8. p38 Mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes.
    Collins QF, Xiong Y, Lupo EG, Liu HY, Cao W.
    J Biol Chem; 2006 Aug 25; 281(34):24336-44. PubMed ID: 16803882
    [Abstract] [Full Text] [Related]

  • 9. IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes.
    Valverde AM, Fabregat I, Burks DJ, White MF, Benito M.
    Hepatology; 2004 Dec 25; 40(6):1285-94. PubMed ID: 15565601
    [Abstract] [Full Text] [Related]

  • 10. Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner.
    de Alvaro C, Teruel T, Hernandez R, Lorenzo M.
    J Biol Chem; 2004 Apr 23; 279(17):17070-8. PubMed ID: 14764603
    [Abstract] [Full Text] [Related]

  • 11. Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase.
    Talukdar I, Szeszel-Fedorowicz W, Salati LM.
    J Biol Chem; 2005 Dec 09; 280(49):40660-7. PubMed ID: 16210322
    [Abstract] [Full Text] [Related]

  • 12. PTEN influences insulin and lipid metabolism in bovine hepatocytes in vitro.
    Deng Q, Ma D, Sun G, Yuan X, Wang Z, Liu G.
    J Dairy Res; 2019 Feb 09; 86(1):73-76. PubMed ID: 30819264
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of IRS-1 by hepatitis C virus infection leads to insulin resistance in a PTEN-dependent manner.
    Gao TT, Qin ZL, Ren H, Zhao P, Qi ZT.
    Virol J; 2015 Feb 03; 12():12. PubMed ID: 25645159
    [Abstract] [Full Text] [Related]

  • 14. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
    [Abstract] [Full Text] [Related]

  • 15. Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.
    Conejo R, Lorenzo M.
    J Cell Physiol; 2001 Apr 10; 187(1):96-108. PubMed ID: 11241354
    [Abstract] [Full Text] [Related]

  • 16. Role of insulin receptor substrate-1 serine 307 phosphorylation and adiponectin in adipose tissue insulin resistance in late pregnancy.
    Sevillano J, de Castro J, Bocos C, Herrera E, Ramos MP.
    Endocrinology; 2007 Dec 10; 148(12):5933-42. PubMed ID: 17823255
    [Abstract] [Full Text] [Related]

  • 17. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N, Makeeva N, Welsh M.
    Mol Med; 2002 Nov 10; 8(11):695-704. PubMed ID: 12520086
    [Abstract] [Full Text] [Related]

  • 18. Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor gamma (PPARgamma), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo.
    Jiang G, Dallas-Yang Q, Biswas S, Li Z, Zhang BB.
    Biochem J; 2004 Jan 15; 377(Pt 2):339-46. PubMed ID: 14556646
    [Abstract] [Full Text] [Related]

  • 19. Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy.
    Rane MJ, Song Y, Jin S, Barati MT, Wu R, Kausar H, Tan Y, Wang Y, Zhou G, Klein JB, Li X, Cai L.
    Am J Physiol Renal Physiol; 2010 Jan 15; 298(1):F49-61. PubMed ID: 19726550
    [Abstract] [Full Text] [Related]

  • 20. Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
    Ruddock MW, Stein A, Landaker E, Park J, Cooksey RC, McClain D, Patti ME.
    J Biochem; 2008 Nov 15; 144(5):599-607. PubMed ID: 18713797
    [Abstract] [Full Text] [Related]

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