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171 related items for PubMed ID: 17395746
1. Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice. Martinic MM, Juedes AE, Bresson D, Homann D, Skak K, Huber C, Ling E, Ejrnaes M, Wolfe T, Togher L, Christen U, von Herrath MG. Diabetes; 2007 Apr; 56(4):1059-68. PubMed ID: 17395746 [Abstract] [Full Text] [Related]
2. "Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes. Serreze DV, Marron MP, Dilorenzo TP. Ann N Y Acad Sci; 2007 Apr; 1103():103-11. PubMed ID: 17376821 [Abstract] [Full Text] [Related]
3. CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. Pang S, Zhang L, Wang H, Yi Z, Li L, Gao L, Zhao J, Tisch R, Katz JD, Wang B. Eur J Immunol; 2009 Oct; 39(10):2716-24. PubMed ID: 19658094 [Abstract] [Full Text] [Related]
4. Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP. Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW. J Clin Invest; 2006 Dec; 116(12):3258-65. PubMed ID: 17143333 [Abstract] [Full Text] [Related]
5. RegII is a beta-cell protein and autoantigen in diabetes of NOD mice. Gurr W, Shaw M, Li Y, Sherwin R. Diabetes; 2007 Jan; 56(1):34-40. PubMed ID: 17192462 [Abstract] [Full Text] [Related]
6. On the pathogenicity of autoantigen-specific T-cell receptors. Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA. Diabetes; 2008 May; 57(5):1321-30. PubMed ID: 18299317 [Abstract] [Full Text] [Related]
7. Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men. Unger WW, Pinkse GG, Mulder-van der Kracht S, van der Slik AR, Kester MG, Ossendorp F, Drijfhout JW, Serreze DV, Roep BO. Ann N Y Acad Sci; 2007 Apr; 1103():192-5. PubMed ID: 17376840 [Abstract] [Full Text] [Related]
8. The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment. Martinuzzi E, Novelli G, Scotto M, Blancou P, Bach JM, Chaillous L, Bruno G, Chatenoud L, van Endert P, Mallone R. Diabetes; 2008 May; 57(5):1312-20. PubMed ID: 18305140 [Abstract] [Full Text] [Related]
9. On how monospecific memory-like autoregulatory CD8+ T cells can blunt diabetogenic autoimmunity: a computational approach. Khadra A, Tsai S, Santamaria P, Edelstein-Keshet L. J Immunol; 2010 Nov 15; 185(10):5962-72. PubMed ID: 20962260 [Abstract] [Full Text] [Related]
13. Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells. Mariño E, Batten M, Groom J, Walters S, Liuwantara D, Mackay F, Grey ST. Diabetes; 2008 Feb 15; 57(2):395-404. PubMed ID: 18025414 [Abstract] [Full Text] [Related]
14. The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation. Khadra A, Santamaria P, Edelstein-Keshet L. J Theor Biol; 2009 Jan 07; 256(1):126-41. PubMed ID: 18950644 [Abstract] [Full Text] [Related]
15. Spontaneous autoimmunity sufficiently potent to induce diabetes mellitus is insufficient to protect against insulinoma. Zwicker K, Chatten C, Gratton K, Demetrick D, Serra P, Shameli A, Santamaria P, Bathe OF. J Immunol; 2009 Aug 01; 183(3):1705-14. PubMed ID: 19570832 [Abstract] [Full Text] [Related]
16. Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes. Han B, Serra P, Yamanouchi J, Amrani A, Elliott JF, Dickie P, Dilorenzo TP, Santamaria P. J Clin Invest; 2005 Jul 01; 115(7):1879-87. PubMed ID: 15937548 [Abstract] [Full Text] [Related]
17. Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes. Pinkse GG, Tysma OH, Bergen CA, Kester MG, Ossendorp F, van Veelen PA, Keymeulen B, Pipeleers D, Drijfhout JW, Roep BO. Proc Natl Acad Sci U S A; 2005 Dec 20; 102(51):18425-30. PubMed ID: 16339897 [Abstract] [Full Text] [Related]
18. DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice. Chang Y, Yap S, Ge X, Piganelli J, Bertera S, Giannokakis N, Mathews C, Prud'homme G, Trucco M. Gene Ther; 2005 Dec 20; 12(23):1679-85. PubMed ID: 16107864 [Abstract] [Full Text] [Related]
19. Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets. Hänninen A, Nurmela R, Maksimow M, Heino J, Jalkanen S, Kurts C. Am J Pathol; 2007 Jan 20; 170(1):240-50. PubMed ID: 17200197 [Abstract] [Full Text] [Related]