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Journal Abstract Search

213 related items for PubMed ID: 17397239

  • 1. Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.
    Wilmes A, Bargh K, Kelly C, Northcote PT, Miller JH.
    Mol Pharm; 2007; 4(2):269-80. PubMed ID: 17397239
    [Abstract] [Full Text] [Related]

  • 2. Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells.
    Wilmes A, O'Sullivan D, Chan A, Chandrahasen C, Paterson I, Northcote PT, La Flamme AC, Miller JH.
    Cancer Chemother Pharmacol; 2011 Jul; 68(1):117-26. PubMed ID: 20848285
    [Abstract] [Full Text] [Related]

  • 3. Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.
    Hamel E, Day BW, Miller JH, Jung MK, Northcote PT, Ghosh AK, Curran DP, Cushman M, Nicolaou KC, Paterson I, Sorensen EJ.
    Mol Pharmacol; 2006 Nov; 70(5):1555-64. PubMed ID: 16887932
    [Abstract] [Full Text] [Related]

  • 4. Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.
    Gaitanos TN, Buey RM, Díaz JF, Northcote PT, Teesdale-Spittle P, Andreu JM, Miller JH.
    Cancer Res; 2004 Aug 01; 64(15):5063-7. PubMed ID: 15289305
    [Abstract] [Full Text] [Related]

  • 5. βII-tubulin and βIII-tubulin mediate sensitivity to peloruside A and laulimalide, but not paclitaxel or vinblastine, in human ovarian carcinoma cells.
    Kanakkanthara A, Northcote PT, Miller JH.
    Mol Cancer Ther; 2012 Feb 01; 11(2):393-404. PubMed ID: 22180309
    [Abstract] [Full Text] [Related]

  • 6. Peloruside A, a novel antimitotic agent with paclitaxel-like microtubule- stabilizing activity.
    Hood KA, West LM, Rouwé B, Northcote PT, Berridge MV, Wakefield SJ, Miller JH.
    Cancer Res; 2002 Jun 15; 62(12):3356-60. PubMed ID: 12067973
    [Abstract] [Full Text] [Related]

  • 7. Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.
    Field JJ, Northcote PT, Paterson I, Altmann KH, Díaz JF, Miller JH.
    Int J Mol Sci; 2017 May 03; 18(5):. PubMed ID: 28467385
    [Abstract] [Full Text] [Related]

  • 8. βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug-tubulin interactions and microtubule stability.
    Kanakkanthara A, Rowe MR, Field JJ, Northcote PT, Teesdale-Spittle PH, Miller JH.
    Cancer Lett; 2015 Sep 01; 365(2):251-60. PubMed ID: 26052091
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of human vascular endothelial cell migration and capillary-like tube formation by the microtubule-stabilizing agent peloruside A.
    Chan A, Singh AJ, Northcote PT, Miller JH.
    Invest New Drugs; 2015 Jun 01; 33(3):564-74. PubMed ID: 25822110
    [Abstract] [Full Text] [Related]

  • 10. A unique mode of microtubule stabilization induced by peloruside A.
    Huzil JT, Chik JK, Slysz GW, Freedman H, Tuszynski J, Taylor RE, Sackett DL, Schriemer DC.
    J Mol Biol; 2008 May 16; 378(5):1016-30. PubMed ID: 18405918
    [Abstract] [Full Text] [Related]

  • 11. Peloruside- and laulimalide-resistant human ovarian carcinoma cells have βI-tubulin mutations and altered expression of βII- and βIII-tubulin isotypes.
    Kanakkanthara A, Wilmes A, O'Brate A, Escuin D, Chan A, Gjyrezi A, Crawford J, Rawson P, Kivell B, Northcote PT, Hamel E, Giannakakou P, Miller JH.
    Mol Cancer Ther; 2011 Aug 16; 10(8):1419-29. PubMed ID: 21653684
    [Abstract] [Full Text] [Related]

  • 12. Computational comparison of microtubule-stabilising agents laulimalide and peloruside with taxol and colchicine.
    Pineda O, Farràs J, Maccari L, Manetti F, Botta M, Vilarrasa J.
    Bioorg Med Chem Lett; 2004 Oct 04; 14(19):4825-9. PubMed ID: 15341932
    [Abstract] [Full Text] [Related]

  • 13. Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease.
    Kanakkanthara A, Northcote PT, Miller JH.
    Nat Prod Rep; 2016 Apr 04; 33(4):549-61. PubMed ID: 26867978
    [Abstract] [Full Text] [Related]

  • 14. Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells.
    Wilmes A, Rawson P, Peng L, McLauchlan D, Northcote PT, Jordan TW, Miller JH.
    Invest New Drugs; 2011 Aug 04; 29(4):544-53. PubMed ID: 20107863
    [Abstract] [Full Text] [Related]

  • 15. Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae.
    Wilmes A, Hanna R, Heathcott RW, Northcote PT, Atkinson PH, Bellows DS, Miller JH.
    Gene; 2012 Apr 15; 497(2):140-6. PubMed ID: 22326528
    [Abstract] [Full Text] [Related]

  • 16. Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.
    Pera B, Razzak M, Trigili C, Pineda O, Canales A, Buey RM, Jiménez-Barbero J, Northcote PT, Paterson I, Barasoain I, Díaz JF.
    Chembiochem; 2010 Aug 16; 11(12):1669-78. PubMed ID: 20665616
    [Abstract] [Full Text] [Related]

  • 17. Induction of accelerated senescence by the microtubule-stabilizing agent peloruside A.
    Chan A, Gilfillan C, Templeton N, Paterson I, Northcote PT, Miller JH.
    Invest New Drugs; 2017 Dec 16; 35(6):706-717. PubMed ID: 28733703
    [Abstract] [Full Text] [Related]

  • 18. Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid-induced tau phosphorylation.
    Das V, Miller JH.
    Eur J Neurosci; 2012 Jun 16; 35(11):1705-17. PubMed ID: 22594877
    [Abstract] [Full Text] [Related]

  • 19. Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.
    Honore S, Kamath K, Braguer D, Horwitz SB, Wilson L, Briand C, Jordan MA.
    Cancer Res; 2004 Jul 15; 64(14):4957-64. PubMed ID: 15256469
    [Abstract] [Full Text] [Related]

  • 20. Delaying the onset of experimental autoimmune encephalomyelitis with the microtubule-stabilizing compounds, paclitaxel and Peloruside A.
    Crume KP, O'Sullivan D, Miller JH, Northcote PT, La Flamme AC.
    J Leukoc Biol; 2009 Oct 15; 86(4):949-58. PubMed ID: 19654226
    [Abstract] [Full Text] [Related]

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