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201 related items for PubMed ID: 17404263

  • 1. Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D.
    Peter D, Jin SL, Conti M, Hatzelmann A, Zitt C.
    J Immunol; 2007 Apr 15; 178(8):4820-31. PubMed ID: 17404263
    [Abstract] [Full Text] [Related]

  • 2. Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B.
    Manning CD, Burman M, Christensen SB, Cieslinski LB, Essayan DM, Grous M, Torphy TJ, Barnette MS.
    Br J Pharmacol; 1999 Dec 15; 128(7):1393-8. PubMed ID: 10602317
    [Abstract] [Full Text] [Related]

  • 3. Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant.
    Erdogan S, Houslay MD.
    Biochem J; 1997 Jan 01; 321 ( Pt 1)(Pt 1):165-75. PubMed ID: 9003416
    [Abstract] [Full Text] [Related]

  • 4. Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation.
    Ariga M, Neitzert B, Nakae S, Mottin G, Bertrand C, Pruniaux MP, Jin SL, Conti M.
    J Immunol; 2004 Dec 15; 173(12):7531-8. PubMed ID: 15585880
    [Abstract] [Full Text] [Related]

  • 5. The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion.
    Selige J, Hatzelmann A, Dunkern T.
    J Cell Physiol; 2011 Aug 15; 226(8):1970-80. PubMed ID: 21520048
    [Abstract] [Full Text] [Related]

  • 6. mRNA expression and antilipolytic role of phosphodiesterase 4 in rat adipocytes in vitro.
    Wang H, Edens NK.
    J Lipid Res; 2007 May 15; 48(5):1099-107. PubMed ID: 17267946
    [Abstract] [Full Text] [Related]

  • 7. Comparison of recombinant human PDE4 isoforms: interaction with substrate and inhibitors.
    Saldou N, Obernolte R, Huber A, Baecker PA, Wilhelm R, Alvarez R, Li B, Xia L, Callan O, Su C, Jarnagin K, Shelton ER.
    Cell Signal; 1998 Jun 15; 10(6):427-40. PubMed ID: 9720765
    [Abstract] [Full Text] [Related]

  • 8. Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.
    Jin SL, Lan L, Zoudilova M, Conti M.
    J Immunol; 2005 Aug 01; 175(3):1523-31. PubMed ID: 16034090
    [Abstract] [Full Text] [Related]

  • 9. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma.
    Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY.
    Eur J Pharmacol; 2006 Oct 10; 547(1-3):125-35. PubMed ID: 16956605
    [Abstract] [Full Text] [Related]

  • 10. Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue.
    Richter W, Jin SL, Conti M.
    Biochem J; 2005 Jun 15; 388(Pt 3):803-11. PubMed ID: 15717866
    [Abstract] [Full Text] [Related]

  • 11. Identification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjects.
    Landells LJ, Szilagy CM, Jones NA, Banner KH, Allen JM, Doherty A, O'Connor BJ, Spina D, Page CP.
    Br J Pharmacol; 2001 Jul 15; 133(5):722-9. PubMed ID: 11429397
    [Abstract] [Full Text] [Related]

  • 12. Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF.
    Pullamsetti SS, Banat GA, Schmall A, Szibor M, Pomagruk D, Hänze J, Kolosionek E, Wilhelm J, Braun T, Grimminger F, Seeger W, Schermuly RT, Savai R.
    Oncogene; 2013 Feb 28; 32(9):1121-34. PubMed ID: 22525277
    [Abstract] [Full Text] [Related]

  • 13. Effect of pregnancy on PDE4 cAMP-specific phosphodiesterase messenger ribonucleic acid expression in human myometrium.
    Leroy MJ, Méhats C, Duc-Goiran P, Tanguy G, Robert B, Dallot E, Mignot TM, Grangé G, Ferré F.
    Cell Signal; 1999 Jan 28; 11(1):31-7. PubMed ID: 10206342
    [Abstract] [Full Text] [Related]

  • 14. Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.
    Manning CD, McLaughlin MM, Livi GP, Cieslinski LB, Torphy TJ, Barnette MS.
    J Pharmacol Exp Ther; 1996 Feb 28; 276(2):810-8. PubMed ID: 8632354
    [Abstract] [Full Text] [Related]

  • 15. Selective up-regulation of phosphodiesterase-4 cyclic adenosine 3',5'-monophosphate (cAMP)-specific phosphodiesterase variants by elevated cAMP content in human myometrial cells in culture.
    Méhats C, Tanguy G, Dallot E, Robert B, Rebourcet R, Ferré F, Leroy MJ.
    Endocrinology; 1999 Jul 28; 140(7):3228-37. PubMed ID: 10385419
    [Abstract] [Full Text] [Related]

  • 16. Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme.
    Zhang HT, Huang Y, Jin SL, Frith SA, Suvarna N, Conti M, O'Donnell JM.
    Neuropsychopharmacology; 2002 Oct 28; 27(4):587-95. PubMed ID: 12377395
    [Abstract] [Full Text] [Related]

  • 17. Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation.
    Ji Q, Di Y, He X, Liu Q, Liu J, Li W, Zhang L.
    Mol Med Rep; 2016 Feb 28; 13(2):1914-22. PubMed ID: 26706904
    [Abstract] [Full Text] [Related]

  • 18. Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis.
    Robichaud A, Stamatiou PB, Jin SL, Lachance N, MacDonald D, Laliberté F, Liu S, Huang Z, Conti M, Chan CC.
    J Clin Invest; 2002 Oct 28; 110(7):1045-52. PubMed ID: 12370283
    [Abstract] [Full Text] [Related]

  • 19. Phosphodiesterase 4B2 is the predominant phosphodiesterase species and undergoes differential regulation of gene expression in human monocytes and neutrophils.
    Wang P, Wu P, Ohleth KM, Egan RW, Billah MM.
    Mol Pharmacol; 1999 Jul 28; 56(1):170-4. PubMed ID: 10385698
    [Abstract] [Full Text] [Related]

  • 20. Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: comparison with rolipram.
    Dlaboga D, Hajjhussein H, O'Donnell JM.
    Brain Res; 2006 Jun 22; 1096(1):104-12. PubMed ID: 16730340
    [Abstract] [Full Text] [Related]

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