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Journal Abstract Search

231 related items for PubMed ID: 17410524

  • 1. In Vitro and In Vivo pharmacokinetic studies of bulaquine (analogue of primaquine), a novel antirelapse antimalarial, in rat, rabbit and monkey--highlighting species similarities and differences.
    Mehrotra N, Lal J, Puri SK, Madhusudanan KP, Gupta RC.
    Biopharm Drug Dispos; 2007 Jul; 28(5):209-27. PubMed ID: 17410524
    [Abstract] [Full Text] [Related]

  • 2. Analysis and pharmacokinetics of bulaquine and its major metabolite primaquine in rabbits using an LC-UV method--a pilot study.
    Lal J, Mehrotra N, Gupta RC.
    J Pharm Biomed Anal; 2003 Apr 24; 32(1):141-50. PubMed ID: 12852456
    [Abstract] [Full Text] [Related]

  • 3. Interspecies comparison of the pharmacokinetics and oral bioavailability of 99-357, a potent synthetic trioxane antimalarial compound.
    Singh RP, Gupta RC, Singh SK.
    Eur J Pharm Sci; 2010 Oct 09; 41(2):312-9. PubMed ID: 20599503
    [Abstract] [Full Text] [Related]

  • 4. Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques.
    Ramanathan-Girish S, Catz P, Creek MR, Wu B, Thomas D, Krogstad DJ, De D, Mirsalis JC, Green CE.
    Int J Toxicol; 2004 Oct 09; 23(3):179-89. PubMed ID: 15204721
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetic properties of TDP4815 after single intravenous and oral administrations to rat, rabbit, monkey, dog and in vitro drug metabolism.
    Chen Y, Cheng D, Tio C, Kagan N, Eisennagel S, Dasgupta M, Tomczuk B, Bone R, Huebert N.
    Biopharm Drug Dispos; 2008 Apr 09; 29(3):127-38. PubMed ID: 18186144
    [Abstract] [Full Text] [Related]

  • 6. Absorption, protein binding, pharmacokinetics and excretion of the anti-ischemic and anti-hypertensive arylpiperazine derivative CDRI-93/478 in rats.
    Lal J, Gupta RC.
    Arzneimittelforschung; 2008 Apr 09; 58(2):62-70. PubMed ID: 18412019
    [Abstract] [Full Text] [Related]

  • 7. Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate.
    Jia L, Coward LC, Kerstner-Wood CD, Cork RL, Gorman GS, Noker PE, Kitada S, Pellecchia M, Reed JC.
    Cancer Chemother Pharmacol; 2008 Jan 09; 61(1):63-73. PubMed ID: 17356822
    [Abstract] [Full Text] [Related]

  • 8. Effects of formulation and route of administration on the systemic availability of Ex-RAD®, a new radioprotectant, in preclinical species.
    Chun AW, Freshwater RE, Taft DR, Gillum AM, Maniar M.
    Biopharm Drug Dispos; 2011 Mar 09; 32(2):99-111. PubMed ID: 21341279
    [Abstract] [Full Text] [Related]

  • 9. A comparison of the pharmacokinetics of perfluorobutanesulfonate (PFBS) in rats, monkeys, and humans.
    Olsen GW, Chang SC, Noker PE, Gorman GS, Ehresman DJ, Lieder PH, Butenhoff JL.
    Toxicology; 2009 Feb 04; 256(1-2):65-74. PubMed ID: 19059455
    [Abstract] [Full Text] [Related]

  • 10. Pharmacokinetic study of the novel, synthetic trioxane antimalarial compound 97-78 in rats using an LC-MS/MS method for quantification.
    Singh RP, Sabarinath S, Gautam N, Gupta RC, Singh SK.
    Arzneimittelforschung; 2011 Feb 04; 61(2):120-5. PubMed ID: 21428247
    [Abstract] [Full Text] [Related]

  • 11. In vivo metabolism and final disposition of a novel nonsteroidal androgen in rats and dogs.
    Perera MA, Yin D, Wu D, Chan KK, Miller DD, Dalton J.
    Drug Metab Dispos; 2006 Oct 04; 34(10):1713-21. PubMed ID: 16815963
    [Abstract] [Full Text] [Related]

  • 12. In vitro and in vivo evaluation of a primaquine prodrug without red blood cell membrane destabilization property.
    Davanço MG, Campos ML, Nogueira MA, Campos SL, Marques RV, dos Santos JL, Chin CM, da Fonseca LM, Peccinini RG.
    Biopharm Drug Dispos; 2012 Nov 04; 33(8):437-45. PubMed ID: 22899089
    [Abstract] [Full Text] [Related]

  • 13. A liquid chromatography-mass spectrometry assay for simultaneous determination of two antimalarial thiazolium compounds in human and rat matrices.
    Taudon N, Margout D, Calas M, Kezutyte T, Vial HJ, Bressolle FM.
    J Pharm Biomed Anal; 2008 Nov 04; 48(3):1001-5. PubMed ID: 18678456
    [Abstract] [Full Text] [Related]

  • 14. Disposition of DMP 811 (L-708,404), a potent angiotensin II receptor antagonist, in the rat, monkey, and chimpanzee.
    Zhang KE, Vyas KP.
    Drug Metab Dispos; 1995 Oct 04; 23(10):1104-9. PubMed ID: 8654199
    [Abstract] [Full Text] [Related]

  • 15. Pharmacokinetics of muraglitazar (BMS-298585), a dual peroxisome proliferator-activated receptors (PPAR) alpha and gamma activator, in mice, rats, dogs, and monkeys.
    Hosagrahara VP, Chandrasena G, Chang SY, Koplowitz B, Hariharan N, Cheng PT, Humphreys WG.
    Xenobiotica; 2006 Dec 04; 36(12):1227-38. PubMed ID: 17162469
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections.
    Fura A, Khanna A, Vyas V, Koplowitz B, Chang SY, Caporuscio C, Boulton DW, Christopher LJ, Chadwick KD, Hamann LG, Humphreys WG, Kirby M.
    Drug Metab Dispos; 2009 Jun 04; 37(6):1164-71. PubMed ID: 19251818
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetics and metabolism in rats, dogs, and monkeys of the cathepsin k inhibitor odanacatib: demethylation of a methylsulfonyl moiety as a major metabolic pathway.
    Kassahun K, Black WC, Nicoll-Griffith D, McIntosh I, Chauret N, Day S, Rosenberg E, Koeplinger K.
    Drug Metab Dispos; 2011 Jun 04; 39(6):1079-87. PubMed ID: 21422190
    [Abstract] [Full Text] [Related]

  • 18. Disposition of vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in rats and dogs.
    He H, Tran P, Yin H, Smith H, Flood D, Kramp R, Filipeck R, Fischer V, Howard D.
    Drug Metab Dispos; 2009 Mar 04; 37(3):545-54. PubMed ID: 19074976
    [Abstract] [Full Text] [Related]

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  • 20. Oral and i.v. pharmacokinetics of isosteviol in rats as assessed by a new sensitive LC-MS/MS method.
    Jin H, Gerber JP, Wang J, Ji M, Davey AK.
    J Pharm Biomed Anal; 2008 Nov 04; 48(3):986-90. PubMed ID: 18701231
    [Abstract] [Full Text] [Related]

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