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287 related items for PubMed ID: 17419949
1. PDGF receptors as targets in tumor treatment. Ostman A, Heldin CH. Adv Cancer Res; 2007; 97():247-74. PubMed ID: 17419949 [Abstract] [Full Text] [Related]
2. Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. Pietras K, Pahler J, Bergers G, Hanahan D. PLoS Med; 2008 Jan 29; 5(1):e19. PubMed ID: 18232728 [Abstract] [Full Text] [Related]
3. Targeting PDGF signaling in carcinoma-associated fibroblasts controls cervical cancer in mouse model. Jain RK, Lahdenranta J, Fukumura D. PLoS Med; 2008 Jan 29; 5(1):e24. PubMed ID: 18232729 [Abstract] [Full Text] [Related]
4. Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation. Servidei T, Riccardi A, Sanguinetti M, Dominici C, Riccardi R. J Cell Physiol; 2006 Jul 29; 208(1):220-8. PubMed ID: 16575905 [Abstract] [Full Text] [Related]
5. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Ostman A. Cytokine Growth Factor Rev; 2004 Aug 29; 15(4):275-86. PubMed ID: 15207817 [Abstract] [Full Text] [Related]
6. The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. Shimizu A, O'Brien KP, Sjöblom T, Pietras K, Buchdunger E, Collins VP, Heldin CH, Dumanski JP, Ostman A. Cancer Res; 1999 Aug 01; 59(15):3719-23. PubMed ID: 10446987 [Abstract] [Full Text] [Related]
7. Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248. Potapova O, Laird AD, Nannini MA, Barone A, Li G, Moss KG, Cherrington JM, Mendel DB. Mol Cancer Ther; 2006 May 01; 5(5):1280-9. PubMed ID: 16731761 [Abstract] [Full Text] [Related]
8. Imatinib mesylate inhibits the proliferation-stimulating effect of human lung cancer-associated stromal fibroblasts on lung cancer cells. Kinoshita K, Nakagawa K, Hamada J, Hida Y, Tada M, Kondo S, Moriuchi T. Int J Oncol; 2010 Oct 01; 37(4):869-77. PubMed ID: 20811709 [Abstract] [Full Text] [Related]
9. Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content. McCarty MF, Somcio RJ, Stoeltzing O, Wey J, Fan F, Liu W, Bucana C, Ellis LM. J Clin Invest; 2007 Aug 01; 117(8):2114-22. PubMed ID: 17641778 [Abstract] [Full Text] [Related]
12. Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model. Sumida T, Kitadai Y, Shinagawa K, Tanaka M, Kodama M, Ohnishi M, Ohara E, Tanaka S, Yasui W, Chayama K. Int J Cancer; 2011 May 01; 128(9):2050-62. PubMed ID: 21387285 [Abstract] [Full Text] [Related]
14. A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. Pietras K, Hanahan D. J Clin Oncol; 2005 Feb 10; 23(5):939-52. PubMed ID: 15557593 [Abstract] [Full Text] [Related]
15. Current management of GIST. Blanke C. Clin Adv Hematol Oncol; 2004 May 10; 2(5):280, 283. PubMed ID: 17682286 [No Abstract] [Full Text] [Related]
16. Platelet-derived growth factor receptors: a therapeutic target in solid tumors. George D. Semin Oncol; 2001 Oct 10; 28(5 Suppl 17):27-33. PubMed ID: 11740804 [Abstract] [Full Text] [Related]
17. Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Pietras K, Ostman A, Sjöquist M, Buchdunger E, Reed RK, Heldin CH, Rubin K. Cancer Res; 2001 Apr 01; 61(7):2929-34. PubMed ID: 11306470 [Abstract] [Full Text] [Related]
18. PDGF BB induces VEGF secretion in ovarian cancer. Matei D, Kelich S, Cao L, Menning N, Emerson RE, Rao J, Jeng MH, Sledge GW. Cancer Biol Ther; 2007 Dec 01; 6(12):1951-9. PubMed ID: 18075302 [Abstract] [Full Text] [Related]
19. Sunitinib for imatinib-resistant GIST. Joensuu H. Lancet; 2006 Oct 14; 368(9544):1303-4. PubMed ID: 17046443 [No Abstract] [Full Text] [Related]
20. Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Pietras K, Rubin K, Sjöblom T, Buchdunger E, Sjöquist M, Heldin CH, Ostman A. Cancer Res; 2002 Oct 01; 62(19):5476-84. PubMed ID: 12359756 [Abstract] [Full Text] [Related] Page: [Next] [New Search]