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314 related items for PubMed ID: 17431115

  • 1. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
    Ray S, Shyam S, Fraizer GC, Almasan A.
    Mol Cancer Ther; 2007 Apr; 6(4):1368-78. PubMed ID: 17431115
    [Abstract] [Full Text] [Related]

  • 2. Apoptosis induction in prostate cancer cells and xenografts by combined treatment with Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11.
    Ray S, Almasan A.
    Cancer Res; 2003 Aug 01; 63(15):4713-23. PubMed ID: 12907654
    [Abstract] [Full Text] [Related]

  • 3. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
    Agarwal C, Tyagi A, Agarwal R.
    Mol Cancer Ther; 2006 Dec 01; 5(12):3294-302. PubMed ID: 17172433
    [Abstract] [Full Text] [Related]

  • 4. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR, Aau MY, Zhuang L, Yu Q.
    J Biol Chem; 2009 Feb 13; 284(7):4132-9. PubMed ID: 19060337
    [Abstract] [Full Text] [Related]

  • 5. PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells.
    Yuan Z, Guo W, Yang J, Li L, Wang M, Lei Y, Wan Y, Zhao X, Luo N, Cheng P, Liu X, Nie C, Peng Y, Tong A, Wei Y.
    J Biol Chem; 2015 Jun 12; 290(24):14927-44. PubMed ID: 25918161
    [Abstract] [Full Text] [Related]

  • 6. Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
    Wang H, Wang X, Zhou XY, Chen DJ, Li GC, Iliakis G, Wang Y.
    Cancer Res; 2002 May 01; 62(9):2483-7. PubMed ID: 11980637
    [Abstract] [Full Text] [Related]

  • 7. S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons.
    Ye W, Blain SW.
    Brain; 2010 Aug 01; 133(Pt 8):2295-312. PubMed ID: 20639548
    [Abstract] [Full Text] [Related]

  • 8. Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways.
    Solier S, Sordet O, Kohn KW, Pommier Y.
    Mol Cell Biol; 2009 Jan 01; 29(1):68-82. PubMed ID: 18955500
    [Abstract] [Full Text] [Related]

  • 9. Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation.
    Kaur M, Agarwal R, Agarwal C.
    Mol Cancer Ther; 2006 May 01; 5(5):1265-74. PubMed ID: 16731759
    [Abstract] [Full Text] [Related]

  • 10. D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
    Juang SH, Lung CC, Hsu PC, Hsu KS, Li YC, Hong PC, Shiah HS, Kuo CC, Huang CW, Wang YC, Huang L, Chen TS, Chen SF, Fu KC, Hsu CL, Lin MJ, Chang CJ, Ashendel CL, Chan TC, Chou KM, Chang JY.
    Mol Cancer Ther; 2007 Jan 01; 6(1):193-202. PubMed ID: 17237279
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells.
    Ivanov VN, Zhou H, Partridge MA, Hei TK.
    Cancer Res; 2009 Apr 15; 69(8):3510-9. PubMed ID: 19351839
    [Abstract] [Full Text] [Related]

  • 12. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.
    Guo N, Faller DV, Vaziri C.
    Cell Growth Differ; 2002 Feb 15; 13(2):77-86. PubMed ID: 11864911
    [Abstract] [Full Text] [Related]

  • 13. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.
    Carcinogenesis; 2005 Nov 15; 26(11):1978-87. PubMed ID: 15975956
    [Abstract] [Full Text] [Related]

  • 14. Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors.
    Xiang H, Fox JA, Totpal K, Aikawa M, Dupree K, Sinicropi D, Lowe J, Escandón E.
    Oncogene; 2002 May 16; 21(22):3611-9. PubMed ID: 12032863
    [Abstract] [Full Text] [Related]

  • 15. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G, Besnard E, Fisher D, Piette J, Dulić V.
    Oncogene; 2011 Oct 13; 30(41):4261-74. PubMed ID: 21532626
    [Abstract] [Full Text] [Related]

  • 16. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
    Falck J, Mailand N, Syljuåsen RG, Bartek J, Lukas J.
    Nature; 2001 Apr 12; 410(6830):842-7. PubMed ID: 11298456
    [Abstract] [Full Text] [Related]

  • 17. Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
    Ravi R, Jain AJ, Schulick RD, Pham V, Prouser TS, Allen H, Mayer EG, Yu H, Pardoll DM, Ashkenazi A, Bedi A.
    Cancer Res; 2004 Dec 15; 64(24):9105-14. PubMed ID: 15604280
    [Abstract] [Full Text] [Related]

  • 18. Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
    Yin MB, Li ZR, Cao S, Durrani FA, Azrak RG, Frank C, Rustum YM.
    Mol Pharmacol; 2004 Jul 15; 66(1):153-60. PubMed ID: 15213307
    [Abstract] [Full Text] [Related]

  • 19. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
    Jin J, Ang XL, Ye X, Livingstone M, Harper JW.
    J Biol Chem; 2008 Jul 11; 283(28):19322-8. PubMed ID: 18480045
    [Abstract] [Full Text] [Related]

  • 20. Bortezomib induces G2-M arrest in human colon cancer cells through ROS-inducible phosphorylation of ATM-CHK1.
    Hong YS, Hong SW, Kim SM, Jin DH, Shin JS, Yoon DH, Kim KP, Lee JL, Heo DS, Lee JS, Kim TW.
    Int J Oncol; 2012 Jul 11; 41(1):76-82. PubMed ID: 22552540
    [Abstract] [Full Text] [Related]

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