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134 related items for PubMed ID: 17446118
1. Structured to reduce the mitogenicity of anti-CD3 antibody based on computer-guided molecular design. Lv M, Li Y, Yu M, Sun Y, Lin Z, Qiao C, Luo Q, Gu X, Huang Y, Feng J, Shen B. Int J Biochem Cell Biol; 2007; 39(6):1142-55. PubMed ID: 17446118 [Abstract] [Full Text] [Related]
2. Construction and characterization of a humanized anti-human CD3 monoclonal antibody 12F6 with effective immunoregulation functions. Li B, Wang H, Dai J, Ji J, Qian W, Zhang D, Hou S, Guo Y. Immunology; 2005 Dec; 116(4):487-98. PubMed ID: 16313362 [Abstract] [Full Text] [Related]
3. The novel non-mitogenic anti-CD3 antibody, mini-yCD3, delivers a partial TCR signal. Lv M, Qiao C, Lin Z, Yu M, Hou C, Sun Y, Li Y, Feng J, Shen B. Int Immunopharmacol; 2010 Feb; 10(2):200-6. PubMed ID: 19913640 [Abstract] [Full Text] [Related]
4. Immunosuppressive properties of anti-CD3 single-chain Fv and diabody. Le Gall F, Reusch U, Moldenhauer G, Little M, Kipriyanov SM. J Immunol Methods; 2004 Feb 01; 285(1):111-27. PubMed ID: 14871540 [Abstract] [Full Text] [Related]
5. Modulation of antigen-specific T cell response by a non-mitogenic anti-CD3 antibody. Li J, Davis J, Bracht M, Carton J, Armstrong J, Gao W, Scallon B, Fung R, Emmell E, Zimmerman M, Griswold DE, Li L. Int Immunopharmacol; 2006 Jun 01; 6(6):880-91. PubMed ID: 16644473 [Abstract] [Full Text] [Related]
6. The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties. Bolt S, Routledge E, Lloyd I, Chatenoud L, Pope H, Gorman SD, Clark M, Waldmann H. Eur J Immunol; 1993 Feb 01; 23(2):403-11. PubMed ID: 8436176 [Abstract] [Full Text] [Related]
7. An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity. Alegre ML, Tso JY, Sattar HA, Smith J, Desalle F, Cole M, Bluestone JA. J Immunol; 1995 Aug 01; 155(3):1544-55. PubMed ID: 7636216 [Abstract] [Full Text] [Related]
12. Sparing of first dose effect of monovalent anti-CD3 antibody used in allograft rejection is associated with diminished release of pro-inflammatory cytokines. Abbs IC, Clark M, Waldmann H, Chatenoud L, Koffman CG, Sacks SH. Ther Immunol; 1994 Dec 15; 1(6):325-31. PubMed ID: 7584508 [Abstract] [Full Text] [Related]
17. Fc receptor binding of anti-CD3 monoclonal antibodies is not essential for immunosuppression, but triggers cytokine-related side effects. Vossen AC, Tibbe GJ, Kroos MJ, van de Winkel JG, Benner R, Savelkoul HF. Eur J Immunol; 1995 Jun 15; 25(6):1492-6. PubMed ID: 7614975 [Abstract] [Full Text] [Related]
18. Phase I evaluation of humanized OKT3: toxicity and immunomodulatory effects of hOKT3gamma4. Richards J, Auger J, Peace D, Gale D, Michel J, Koons A, Haverty T, Zivin R, Jolliffe L, Bluestone JA. Cancer Res; 1999 May 01; 59(9):2096-101. PubMed ID: 10232594 [Abstract] [Full Text] [Related]