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194 related items for PubMed ID: 17448567

  • 1. Intestinal bile salt absorption in Atp8b1 deficient mice.
    Groen A, Kunne C, Paulusma CC, Kramer W, Agellon LB, Bull LN, Oude Elferink RP.
    J Hepatol; 2007 Jul; 47(1):114-22. PubMed ID: 17448567
    [Abstract] [Full Text] [Related]

  • 2. A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion.
    Pawlikowska L, Groen A, Eppens EF, Kunne C, Ottenhoff R, Looije N, Knisely AS, Killeen NP, Bull LN, Elferink RP, Freimer NB.
    Hum Mol Genet; 2004 Apr 15; 13(8):881-92. PubMed ID: 14976163
    [Abstract] [Full Text] [Related]

  • 3. The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells.
    van der Mark VA, de Waart DR, Ho-Mok KS, Tabbers MM, Voogt HW, Oude Elferink RP, Knisely AS, Paulusma CC.
    Biochim Biophys Acta; 2014 Dec 15; 1842(12 Pt A):2378-86. PubMed ID: 25239307
    [Abstract] [Full Text] [Related]

  • 4. Increased serum concentrations of secondary bile salts during cholate feeding are due to coprophagy. A study with wild-type and Atp8b1-deficient mice.
    Groen A, Kunne C, Oude Elferink RP.
    Mol Pharm; 2006 Dec 15; 3(6):756-61. PubMed ID: 17140263
    [Abstract] [Full Text] [Related]

  • 5. Activation of CFTR by ASBT-mediated bile salt absorption.
    Bijvelds MJ, Jorna H, Verkade HJ, Bot AG, Hofmann F, Agellon LB, Sinaasappel M, de Jonge HR.
    Am J Physiol Gastrointest Liver Physiol; 2005 Nov 15; 289(5):G870-9. PubMed ID: 16037545
    [Abstract] [Full Text] [Related]

  • 6. Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport.
    Paulusma CC, Groen A, Kunne C, Ho-Mok KS, Spijkerboer AL, Rudi de Waart D, Hoek FJ, Vreeling H, Hoeben KA, van Marle J, Pawlikowska L, Bull LN, Hofmann AF, Knisely AS, Oude Elferink RP.
    Hepatology; 2006 Jul 15; 44(1):195-204. PubMed ID: 16799980
    [Abstract] [Full Text] [Related]

  • 7. Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.
    Martínez-Fernández P, Hierro L, Jara P, Alvarez L.
    Am J Physiol Gastrointest Liver Physiol; 2009 May 15; 296(5):G1119-29. PubMed ID: 19228886
    [Abstract] [Full Text] [Related]

  • 8. Abcg5/8 independent biliary cholesterol excretion in Atp8b1-deficient mice.
    Groen A, Kunne C, Jongsma G, van den Oever K, Mok KS, Petruzzelli M, Vrins CL, Bull L, Paulusma CC, Oude Elferink RP.
    Gastroenterology; 2008 Jun 15; 134(7):2091-100. PubMed ID: 18466903
    [Abstract] [Full Text] [Related]

  • 9. Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation.
    Demeilliers C, Jacquemin E, Barbu V, Mergey M, Paye F, Fouassier L, Chignard N, Housset C, Lomri NE.
    Hepatology; 2006 May 15; 43(5):1125-34. PubMed ID: 16628629
    [Abstract] [Full Text] [Related]

  • 10. Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis.
    Kunne C, de Graaff M, Duijst S, de Waart DR, Oude Elferink RP, Paulusma CC.
    Lab Invest; 2014 Oct 15; 94(10):1103-13. PubMed ID: 25068656
    [Abstract] [Full Text] [Related]

  • 11. Na+ -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice.
    Slijepcevic D, Roscam Abbing RLP, Fuchs CD, Haazen LCM, Beuers U, Trauner M, Oude Elferink RPJ, van de Graaf SFJ.
    Hepatology; 2018 Sep 15; 68(3):1057-1069. PubMed ID: 29572910
    [Abstract] [Full Text] [Related]

  • 12. Bile acid-induced negative feedback regulation of the human ileal bile acid transporter.
    Neimark E, Chen F, Li X, Shneider BL.
    Hepatology; 2004 Jul 15; 40(1):149-56. PubMed ID: 15239098
    [Abstract] [Full Text] [Related]

  • 13. Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter.
    Arrese M, Trauner M, Sacchiero RJ, Crossman MW, Shneider BL.
    Hepatology; 1998 Oct 15; 28(4):1081-7. PubMed ID: 9755246
    [Abstract] [Full Text] [Related]

  • 14. Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity.
    Chen F, Ananthanarayanan M, Emre S, Neimark E, Bull LN, Knisely AS, Strautnieks SS, Thompson RJ, Magid MS, Gordon R, Balasubramanian N, Suchy FJ, Shneider BL.
    Gastroenterology; 2004 Mar 15; 126(3):756-64. PubMed ID: 14988830
    [Abstract] [Full Text] [Related]

  • 15. ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.
    Cai SY, Gautam S, Nguyen T, Soroka CJ, Rahner C, Boyer JL.
    Gastroenterology; 2009 Mar 15; 136(3):1060-9. PubMed ID: 19027009
    [Abstract] [Full Text] [Related]

  • 16. Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice.
    Hulzebos CV, Voshol PJ, Wolters H, Kruit JK, Ottenhof R, Groen AK, Stellaard F, Verkade HJ, Kuipers F.
    Liver Int; 2005 Jun 15; 25(3):604-12. PubMed ID: 15910498
    [Abstract] [Full Text] [Related]

  • 17. Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids.
    Miyata M, Yamakawa H, Hayashi K, Kuribayashi H, Yamazoe Y, Yoshinari K.
    Eur J Pharmacol; 2013 Aug 15; 714(1-3):507-14. PubMed ID: 23872411
    [Abstract] [Full Text] [Related]

  • 18. Impact of Inhibiting Ileal Apical versus Basolateral Bile Acid Transport on Cholesterol Metabolism and Atherosclerosis in Mice.
    Dawson PA.
    Dig Dis; 2015 Aug 15; 33(3):382-7. PubMed ID: 26045273
    [Abstract] [Full Text] [Related]

  • 19. Enterobacteria-mediated deconjugation of taurocholic acid enhances ileal farnesoid X receptor signaling.
    Kuribayashi H, Miyata M, Yamakawa H, Yoshinari K, Yamazoe Y.
    Eur J Pharmacol; 2012 Dec 15; 697(1-3):132-8. PubMed ID: 23051670
    [Abstract] [Full Text] [Related]

  • 20. Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction: role of bile acids.
    Kalia N, Hardcastle J, Keating C, Grasa L, Keating C, Pelegrin P, Bardhan KD, Grundy D.
    Gut; 2008 Jan 15; 57(1):41-9. PubMed ID: 17675326
    [Abstract] [Full Text] [Related]

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