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PUBMED FOR HANDHELDS

Journal Abstract Search


201 related items for PubMed ID: 17448659

  • 1. Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists.
    Balavoine F, Malabre P, Alleaume T, Rey A, Cherfils V, Jeanneton O, Seigneurin-Venin S, Revah F.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3754-9. PubMed ID: 17448659
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  • 2. Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists.
    Dyck B, Zhao L, Tamiya J, Pontillo J, Hudson S, Ching B, Heise CE, Wen J, Norton C, Madan A, Schwarz D, Wade W, Goodfellow VS.
    Bioorg Med Chem Lett; 2006 Aug 15; 16(16):4237-42. PubMed ID: 16762549
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  • 3. Thienopyrimidinone bis-aminopyrrolidine ureas as potent melanin-concentrating hormone receptor-1 (MCH-R1) antagonists.
    Zhang M, Tamiya J, Nguyen L, Rowbottom MW, Dyck B, Vickers TD, Grey J, Schwarz DA, Heise CE, Haelewyn J, Mistry MS, Goodfellow VS.
    Bioorg Med Chem Lett; 2007 May 01; 17(9):2535-9. PubMed ID: 17329101
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  • 6. Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists.
    Ma V, Bannon AW, Baumgartner J, Hale C, Hsieh F, Hulme C, Rorrer K, Salon J, van Staden C, Tempest P.
    Bioorg Med Chem Lett; 2006 Oct 01; 16(19):5066-72. PubMed ID: 16887348
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  • 7. Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).
    Rowbottom MW, Vickers TD, Tamiya J, Zhang M, Dyck B, Grey J, Schwarz D, Heise CE, Hedrick M, Wen J, Tang H, Wang H, Fisher A, Aparicio A, Saunders J, Goodfellow VS.
    Bioorg Med Chem Lett; 2007 Apr 15; 17(8):2171-8. PubMed ID: 17350839
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  • 10. Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists.
    Wu WL, Burnett DA, Caplen MA, Domalski MS, Bennett C, Greenlee WJ, Hawes BE, O'Neill K, Weig B, Weston D, Spar B, Kowalski T.
    Bioorg Med Chem Lett; 2006 Jul 15; 16(14):3674-8. PubMed ID: 16690315
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  • 12. The use of three-dimensional shape and electrostatic similarity searching in the identification of a melanin-concentrating hormone receptor 1 antagonist.
    Muchmore SW, Souers AJ, Akritopoulou-Zanze I.
    Chem Biol Drug Des; 2006 Feb 15; 67(2):174-6. PubMed ID: 16492165
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  • 14. Tandem optimization of target activity and elimination of mutagenic potential in a potent series of N-aryl bicyclic hydantoin-based selective androgen receptor modulators.
    Hamann LG, Manfredi MC, Sun C, Krystek SR, Huang Y, Bi Y, Augeri DJ, Wang T, Zou Y, Betebenner DA, Fura A, Seethala R, Golla R, Kuhns JE, Lupisella JA, Darienzo CJ, Custer LL, Price JL, Johnson JM, Biller SA, Zahler R, Ostrowski J.
    Bioorg Med Chem Lett; 2007 Apr 01; 17(7):1860-4. PubMed ID: 17292608
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  • 15. 4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists.
    Receveur JM, Bjurling E, Ulven T, Little PB, Nørregaard PK, Högberg T.
    Bioorg Med Chem Lett; 2004 Oct 18; 14(20):5075-80. PubMed ID: 15380202
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  • 16. Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1.
    Rowbottom MW, Vickers TD, Dyck B, Grey J, Tamiya J, Zhang M, Kiankarimi M, Wu D, Dwight W, Wade WS, Schwarz D, Heise CE, Madan A, Fisher A, Petroski R, Goodfellow VS.
    Bioorg Med Chem Lett; 2006 Sep 01; 16(17):4450-7. PubMed ID: 16814542
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  • 17. Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.
    Cavasotto CN, Orry AJ, Murgolo NJ, Czarniecki MF, Kocsi SA, Hawes BE, O'Neill KA, Hine H, Burton MS, Voigt JH, Abagyan RA, Bayne ML, Monsma FJ.
    J Med Chem; 2008 Feb 14; 51(3):581-8. PubMed ID: 18198821
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