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Journal Abstract Search

252 related items for PubMed ID: 17456772

  • 1. Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles.
    Caccamo A, Oddo S, Tran LX, LaFerla FM.
    Am J Pathol; 2007 May; 170(5):1669-75. PubMed ID: 17456772
    [Abstract] [Full Text] [Related]

  • 2. A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer's disease.
    Onishi T, Iwashita H, Uno Y, Kunitomo J, Saitoh M, Kimura E, Fujita H, Uchiyama N, Kori M, Takizawa M.
    J Neurochem; 2011 Dec; 119(6):1330-40. PubMed ID: 21992552
    [Abstract] [Full Text] [Related]

  • 3. Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.
    Engel T, Goñi-Oliver P, Lucas JJ, Avila J, Hernández F.
    J Neurochem; 2006 Dec; 99(6):1445-55. PubMed ID: 17059563
    [Abstract] [Full Text] [Related]

  • 4. Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice.
    Blanchard J, Wanka L, Tung YC, Cárdenas-Aguayo Mdel C, LaFerla FM, Iqbal K, Grundke-Iqbal I.
    Acta Neuropathol; 2010 Nov; 120(5):605-21. PubMed ID: 20697724
    [Abstract] [Full Text] [Related]

  • 5. Treating the lesions, not the disease.
    Zhu X, Avila J, Perry G, Smith MA.
    Am J Pathol; 2007 May; 170(5):1457-9. PubMed ID: 17456753
    [No Abstract] [Full Text] [Related]

  • 6. Chronic lithium treatment decreases tau lesions by promoting ubiquitination in a mouse model of tauopathies.
    Nakashima H, Ishihara T, Suguimoto P, Yokota O, Oshima E, Kugo A, Terada S, Hamamura T, Trojanowski JQ, Lee VM, Kuroda S.
    Acta Neuropathol; 2005 Dec; 110(6):547-56. PubMed ID: 16228182
    [Abstract] [Full Text] [Related]

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  • 8. Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice.
    Plaschke K, Kopitz J, Siegelin M, Schliebs R, Salkovic-Petrisic M, Riederer P, Hoyer S.
    J Alzheimers Dis; 2010 Dec; 19(2):691-704. PubMed ID: 20110613
    [Abstract] [Full Text] [Related]

  • 9. Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.
    Ma QL, Lim GP, Harris-White ME, Yang F, Ambegaokar SS, Ubeda OJ, Glabe CG, Teter B, Frautschy SA, Cole GM.
    J Neurosci Res; 2006 Feb 15; 83(3):374-84. PubMed ID: 16385556
    [Abstract] [Full Text] [Related]

  • 10. α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles.
    Medeiros R, Castello NA, Cheng D, Kitazawa M, Baglietto-Vargas D, Green KN, Esbenshade TA, Bitner RS, Decker MW, LaFerla FM.
    Am J Pathol; 2014 Feb 15; 184(2):520-9. PubMed ID: 24269557
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Early Growth Response 1 in the Hippocampus Alleviates Neuropathology and Improves Cognition in an Alzheimer Model with Plaques and Tangles.
    Qin X, Wang Y, Paudel HK.
    Am J Pathol; 2017 Aug 15; 187(8):1828-1847. PubMed ID: 28641077
    [Abstract] [Full Text] [Related]

  • 12. Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576.
    Chauhan NB, Siegel GJ, Feinstein DL.
    Neuropharmacology; 2005 Jan 15; 48(1):93-104. PubMed ID: 15617731
    [Abstract] [Full Text] [Related]

  • 13. Can lithium or valproate untie tangles in Alzheimer's disease?
    Tariot PN, Aisen PS.
    J Clin Psychiatry; 2009 Jun 15; 70(6):919-21. PubMed ID: 19573485
    [No Abstract] [Full Text] [Related]

  • 14. Peripheral Administration of GSK-3β Antisense Oligonucleotide Improves Learning and Memory in SAMP8 and Tg2576 Mouse Models of Alzheimer's Disease.
    Farr SA, Sandoval KE, Niehoff ML, Witt KA, Kumar VB, Morley JE.
    J Alzheimers Dis; 2016 Oct 18; 54(4):1339-1348. PubMed ID: 27589526
    [Abstract] [Full Text] [Related]

  • 15. Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice.
    Oddo S, Caccamo A, Cheng D, Jouleh B, Torp R, LaFerla FM.
    J Neurochem; 2007 Aug 18; 102(4):1053-63. PubMed ID: 17472708
    [Abstract] [Full Text] [Related]

  • 16. A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.
    Serenó L, Coma M, Rodríguez M, Sánchez-Ferrer P, Sánchez MB, Gich I, Agulló JM, Pérez M, Avila J, Guardia-Laguarta C, Clarimón J, Lleó A, Gómez-Isla T.
    Neurobiol Dis; 2009 Sep 18; 35(3):359-67. PubMed ID: 19523516
    [Abstract] [Full Text] [Related]

  • 17. Isoorientin, a GSK-3β inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice.
    Tan X, Liang Z, Li Y, Zhi Y, Yi L, Bai S, Forest KH, Nichols RA, Dong Y, Li QX.
    Behav Brain Res; 2021 Feb 01; 398():112968. PubMed ID: 33069740
    [Abstract] [Full Text] [Related]

  • 18. Alzheimer's disease: Mental plaque removal.
    De Strooper B, Woodgett J.
    Nature; 2003 May 22; 423(6938):392-3. PubMed ID: 12761533
    [No Abstract] [Full Text] [Related]

  • 19. Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease.
    Hurtado DE, Molina-Porcel L, Carroll JC, Macdonald C, Aboagye AK, Trojanowski JQ, Lee VM.
    J Neurosci; 2012 May 23; 32(21):7392-402. PubMed ID: 22623685
    [Abstract] [Full Text] [Related]

  • 20. Role of glycogen synthase kinase-3 in Alzheimer's disease pathogenesis and glycogen synthase kinase-3 inhibitors.
    Avila J, Wandosell F, Hernández F.
    Expert Rev Neurother; 2010 May 23; 10(5):703-10. PubMed ID: 20420491
    [Abstract] [Full Text] [Related]

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