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113 related items for PubMed ID: 1747374

  • 1. Development of affinity labeling agents based on nonsteroidal anti-inflammatory drugs: labeling of the nonsteroidal anti-inflammatory drug binding site of 3 alpha-hydroxysteroid dehydrogenase.
    Askonas LJ, Penning TM.
    Biochemistry; 1991 Dec 10; 30(49):11553-60. PubMed ID: 1747374
    [Abstract] [Full Text] [Related]

  • 2. Bromoacetamido analogs of indomethacin and mefenamic acid as affinity-labeling agents and mechanistic probes for prostaglandin H2 synthase.
    Tang MS, Askonas LJ, Penning TM.
    Biochemistry; 1995 Jan 24; 34(3):808-15. PubMed ID: 7827039
    [Abstract] [Full Text] [Related]

  • 3. Affinity-labelling of the anti-inflammatory drug and prostaglandin-binding site of 3 alpha-hydroxysteroid dehydrogenase of rat liver cytosol with 17 beta- and 21-bromoacetoxysteroids.
    Penning TM, Carlson KE, Sharp RB.
    Biochem J; 1987 Jul 01; 245(1):269-76. PubMed ID: 3478045
    [Abstract] [Full Text] [Related]

  • 4. The kinetic mechanism catalysed by homogeneous rat liver 3 alpha-hydroxysteroid dehydrogenase. Evidence for binary and ternary dead-end complexes containing non-steroidal anti-inflammatory drugs.
    Askonas LJ, Ricigliano JW, Penning TM.
    Biochem J; 1991 Sep 15; 278 ( Pt 3)(Pt 3):835-41. PubMed ID: 1898369
    [Abstract] [Full Text] [Related]

  • 5. Affinity labeling of 3 alpha-hydroxysteroid dehydrogenase with 3 alpha-bromoacetoxyandrosterone and 11 alpha-bromoacetoxyprogesterone. Isolation and sequence of active site peptides containing reactive cysteines; sequence confirmation using nucleotide sequence from a cDNA clone.
    Penning TM, Abrams WR, Pawlowski JE.
    J Biol Chem; 1991 May 15; 266(14):8826-34. PubMed ID: 2026597
    [Abstract] [Full Text] [Related]

  • 6. Isolation and partial characterization of a full-length cDNA clone for 3 alpha-hydroxysteroid dehydrogenase: a potential target enzyme for nonsteroidal anti-inflammatory drugs.
    Pawlowski J, Huizinga M, Penning TM.
    Agents Actions; 1991 Sep 15; 34(1-2):289-93. PubMed ID: 1793046
    [Abstract] [Full Text] [Related]

  • 7. Cloning and sequencing of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
    Pawlowski JE, Huizinga M, Penning TM.
    J Biol Chem; 1991 May 15; 266(14):8820-5. PubMed ID: 1840601
    [Abstract] [Full Text] [Related]

  • 8. Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
    Gobec S, Brozic P, Rizner TL.
    Bioorg Med Chem Lett; 2005 Dec 01; 15(23):5170-5. PubMed ID: 16183274
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and evaluation of non-steroidal mechanism-based inactivators of 3 alpha-hydroxysteroid dehydrogenase.
    Ricigliano JW, Penning TM.
    Biochem J; 1989 Aug 15; 262(1):139-49. PubMed ID: 2640566
    [Abstract] [Full Text] [Related]

  • 10. Clues to the development of mechanism-based inactivators of 3 alpha-hydroxysteroid dehydrogenase: comparison of steroidal and nonsteroidal Michael acceptors and epoxides.
    Penning TM, Thronton R, Ricigliano JW.
    Steroids; 1991 Aug 15; 56(8):420-7. PubMed ID: 1788860
    [Abstract] [Full Text] [Related]

  • 11. Purification and properties of 3 alpha-hydroxysteroid dehydrogenase from rat brain cytosol. Inhibition by nonsteroidal anti-inflammatory drugs and progestins.
    Penning TM, Sharp RB, Krieger NR.
    J Biol Chem; 1985 Dec 05; 260(28):15266-72. PubMed ID: 2933398
    [Abstract] [Full Text] [Related]

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  • 13. Evidence that enzyme-generated aromatic Michael acceptors covalently modify the nucleotide-binding site of 3 alpha-hydroxysteroid dehydrogenase.
    Ricigliano JW, Penning TM.
    Biochem J; 1990 Aug 01; 269(3):749-55. PubMed ID: 2390066
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  • 15. Inhibition of a major NAD(P)-linked oxidoreductase from rat liver cytosol by steroidal and nonsteroidal anti-inflammatory agents and by prostaglandins.
    Penning TM, Talalay P.
    Proc Natl Acad Sci U S A; 1983 Jul 01; 80(14):4504-8. PubMed ID: 6410393
    [Abstract] [Full Text] [Related]

  • 16. Affinity labeling of bovine adrenal 3 beta-hydroxysteroid dehydrogenase/steroid isomerase by 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
    Rutherfurd KJ, Chen SA, Shively JE.
    Biochemistry; 1991 Aug 20; 30(33):8116-23. PubMed ID: 1868087
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of hepatic 17 beta- and 3 alpha-hydroxysteroid dehydrogenases by antiinflammatory drugs and nonsteroidal estrogens.
    Hasebe K, Hara A, Nakayama T, Hayashibara M, Inoue Y, Sawada H.
    Enzyme; 1987 Aug 20; 37(3):109-14. PubMed ID: 3034566
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  • 19. Purification and properties of a 3 alpha-hydroxysteroid dehydrogenase of rat liver cytosol and its inhibition by anti-inflammatory drugs.
    Penning TM, Mukharji I, Barrows S, Talalay P.
    Biochem J; 1984 Sep 15; 222(3):601-11. PubMed ID: 6435601
    [Abstract] [Full Text] [Related]

  • 20. Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2.
    Hata AN, Lybrand TP, Marnett LJ, Breyer RM.
    Mol Pharmacol; 2005 Mar 15; 67(3):640-7. PubMed ID: 15563582
    [Abstract] [Full Text] [Related]

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