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Journal Abstract Search


174 related items for PubMed ID: 17485500

  • 1. Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers).
    Dong Y, Creek D, Chollet J, Matile H, Charman SA, Wittlin S, Wood JK, Vennerstrom JL.
    Antimicrob Agents Chemother; 2007 Aug; 51(8):3033-5. PubMed ID: 17485500
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  • 3. Synthesis and antimalarial activity of dihydroperoxides and tetraoxanes conjugated with bis(benzyl)acetone derivatives.
    Franco LL, de Almeida MV, E Silva LF, Vieira PP, Pohlit AM, Valle MS.
    Chem Biol Drug Des; 2012 May; 79(5):790-7. PubMed ID: 22284812
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  • 4. Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
    Ellis GL, Amewu R, Sabbani S, Stocks PA, Shone A, Stanford D, Gibbons P, Davies J, Vivas L, Charnaud S, Bongard E, Hall C, Rimmer K, Lozanom S, Jesús M, Gargallo D, Ward SA, O'Neill PM.
    J Med Chem; 2008 Apr 10; 51(7):2170-7. PubMed ID: 18341274
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  • 5. Tetraoxanes as antimalarials: harnessing the endoperoxide.
    Fisher LC, Blackie MA.
    Mini Rev Med Chem; 2014 Feb 10; 14(2):123-35. PubMed ID: 24456270
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  • 7. Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.
    Vennerstrom JL, Fu HN, Ellis WY, Ager AL, Wood JK, Andersen SL, Gerena L, Milhous WK.
    J Med Chem; 1992 Aug 07; 35(16):3023-7. PubMed ID: 1501229
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  • 8. Tetraoxanes: synthetic and medicinal chemistry perspective.
    Kumar N, Singh R, Rawat DS.
    Med Res Rev; 2012 May 07; 32(3):581-610. PubMed ID: 22675731
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  • 9. Synthesis, antimalarial activity and cytotoxicity of substituted 3,6-diphenyl-[1,2,4,5]tetraoxanes.
    Kumar N, Khan SI, Beena, Rajalakshmi G, Kumaradhas P, Rawat DS.
    Bioorg Med Chem; 2009 Aug 01; 17(15):5632-8. PubMed ID: 19574054
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  • 10. Synthesis, thermal stability, antimalarial activity of symmetrically and asymmetrically substituted tetraoxanes.
    Atheaya H, Khan SI, Mamgain R, Rawat DS.
    Bioorg Med Chem Lett; 2008 Feb 15; 18(4):1446-9. PubMed ID: 18248990
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  • 11. New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton.
    Opsenica I, Opsenica D, Lanteri CA, Anova L, Milhous WK, Smith KS, Solaja BA.
    J Med Chem; 2008 Oct 09; 51(19):6216-9. PubMed ID: 18774792
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  • 13. Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
    Amewu RK, Chadwick J, Hussain A, Panda S, Rinki R, Janneh O, Ward SA, Miguel C, Burrell-Saward H, Vivas L, O'Neill PM.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7392-7. PubMed ID: 24148834
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  • 14. An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity.
    Ellis GL, Amewu R, Hall C, Rimmer K, Ward SA, O'Neill PM.
    Bioorg Med Chem Lett; 2008 Mar 01; 18(5):1720-4. PubMed ID: 18243702
    [Abstract] [Full Text] [Related]

  • 15. 1,2,4,5-Tetraoxane derivatives/hybrids as potent antimalarial endoperoxides: Chronological advancements, structure-activity relationship (SAR) studies and future perspectives.
    T A AR, Rajendra TN, Suhas KP, Ippagunta SK, Chaudhary S.
    Med Res Rev; 2024 Sep 01; 44(5):2266-2290. PubMed ID: 38618882
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups.
    Dong Y, Matile H, Chollet J, Kaminsky R, Wood JK, Vennerstrom JL.
    J Med Chem; 1999 Apr 22; 42(8):1477-80. PubMed ID: 10212135
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  • 17. Influence of stereoisomer of dispiro-1,2,4,5-tetraoxanes on their binding mode with heme and on antimalarial activity: molecular docking studies.
    Tonmunphean S, Wijitkosoom A, Tantirungrotechai Y.
    Bioorg Med Chem; 2004 May 01; 12(9):2005-12. PubMed ID: 15080904
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  • 18. Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
    Skytte DM, Nielsen SF, Chen M, Zhai L, Olsen CE, Christensen SB.
    J Med Chem; 2006 Jan 12; 49(1):436-40. PubMed ID: 16392829
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  • 19. Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.
    Chadwick J, Amewu RK, Marti F, Garah FB, Sharma R, Berry NG, Stocks PA, Burrell-Saward H, Wittlin S, Rottmann M, Brun R, Taramelli D, Parapini S, Ward SA, O'Neill PM.
    ChemMedChem; 2011 Aug 01; 6(8):1357-61. PubMed ID: 21692184
    [No Abstract] [Full Text] [Related]

  • 20. New antimalarial norterpene cyclic peroxides from Xisha Islands sponge Diacarnus megaspinorhabdosa.
    Yang F, Wang RP, Xu B, Yu HB, Ma GY, Wang GF, Dai SW, Zhang W, Jiao WH, Song SJ, Lin HW.
    Bioorg Med Chem Lett; 2016 Apr 15; 26(8):2084-7. PubMed ID: 26965857
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