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175 related items for PubMed ID: 17489739

  • 1. Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema.
    Doucet A, Bouchard D, Janelle MF, Bellemare A, Gagné S, Tremblay GM, Bourbonnais Y.
    Biochem J; 2007 Aug 01; 405(3):455-63. PubMed ID: 17489739
    [Abstract] [Full Text] [Related]

  • 2. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
    Tsunemi M, Matsuura Y, Sakakibara S, Katsube Y.
    Biochemistry; 1996 Sep 10; 35(36):11570-6. PubMed ID: 8794736
    [Abstract] [Full Text] [Related]

  • 3. Neutrophil influx into the lungs of beige mice is followed by elastolytic damage and emphysema.
    Cavarra E, Martorana PA, de Santi M, Bartalesi B, Cortese S, Gambelli F, Lungarella G.
    Am J Respir Cell Mol Biol; 1999 Feb 10; 20(2):264-9. PubMed ID: 9922217
    [Abstract] [Full Text] [Related]

  • 4. Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3.
    Nobar SM, Zani ML, Boudier C, Moreau T, Bieth JG.
    FEBS J; 2005 Nov 10; 272(22):5883-93. PubMed ID: 16279952
    [Abstract] [Full Text] [Related]

  • 5. Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase.
    Guyot N, Zani ML, Maurel MC, Dallet-Choisy S, Moreau T.
    Biochemistry; 2005 Nov 29; 44(47):15610-8. PubMed ID: 16300411
    [Abstract] [Full Text] [Related]

  • 6. Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris.
    Zani ML, Nobar SM, Lacour SA, Lemoine S, Boudier C, Bieth JG, Moreau T.
    Eur J Biochem; 2004 Jun 29; 271(12):2370-8. PubMed ID: 15182352
    [Abstract] [Full Text] [Related]

  • 7. Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema.
    Janelle MF, Doucet A, Bouchard D, Bourbonnais Y, Tremblay GM.
    Biol Chem; 2006 Jul 29; 387(7):903-9. PubMed ID: 16913840
    [Abstract] [Full Text] [Related]

  • 8. Human pre-elafin inhibits a Pseudomonas aeruginosa-secreted peptidase and prevents its proliferation in complex media.
    Bellemare A, Vernoux N, Morisset D, Bourbonnais Y.
    Antimicrob Agents Chemother; 2008 Feb 29; 52(2):483-90. PubMed ID: 18025118
    [Abstract] [Full Text] [Related]

  • 9. Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases.
    Zani ML, Baranger K, Guyot N, Dallet-Choisy S, Moreau T.
    Protein Sci; 2009 Mar 29; 18(3):579-94. PubMed ID: 19241385
    [Abstract] [Full Text] [Related]

  • 10. Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.
    Sallenave JM, Shulmann J, Crossley J, Jordana M, Gauldie J.
    Am J Respir Cell Mol Biol; 1994 Dec 29; 11(6):733-41. PubMed ID: 7946401
    [Abstract] [Full Text] [Related]

  • 11. Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
    Motta JP, Magne L, Descamps D, Rolland C, Squarzoni-Dale C, Rousset P, Martin L, Cenac N, Balloy V, Huerre M, Fröhlich LF, Jenne D, Wartelle J, Belaaouaj A, Mas E, Vinel JP, Alric L, Chignard M, Vergnolle N, Sallenave JM.
    Gastroenterology; 2011 Apr 29; 140(4):1272-82. PubMed ID: 21199654
    [Abstract] [Full Text] [Related]

  • 12. Anti-inflammatory effect of pre-elafin in lipopolysaccharide-induced acute lung inflammation.
    Vachon E, Bourbonnais Y, Bingle CD, Rowe SJ, Janelle MF, Tremblay GM.
    Biol Chem; 2002 Apr 29; 383(7-8):1249-56. PubMed ID: 12437112
    [Abstract] [Full Text] [Related]

  • 13. Neutrophil recruitment into the lungs is associated with increased lung elastase burden, decreased lung elastin, and emphysema in alpha 1 proteinase inhibitor-deficient mice.
    Cavarra E, Martorana PA, Gambelli F, de Santi M, van Even P, Lungarella G.
    Lab Invest; 1996 Aug 29; 75(2):273-80. PubMed ID: 8765327
    [Abstract] [Full Text] [Related]

  • 14. The antimicrobial/elastase inhibitor elafin regulates lung dendritic cells and adaptive immunity.
    Roghanian A, Williams SE, Sheldrake TA, Brown TI, Oberheim K, Xing Z, Howie SE, Sallenave JM.
    Am J Respir Cell Mol Biol; 2006 May 29; 34(5):634-42. PubMed ID: 16424380
    [Abstract] [Full Text] [Related]

  • 15. Secretion of mucus proteinase inhibitor and elafin by Clara cell and type II pneumocyte cell lines.
    Sallenave JM, Silva A, Marsden ME, Ryle AP.
    Am J Respir Cell Mol Biol; 1993 Feb 29; 8(2):126-33. PubMed ID: 8427705
    [Abstract] [Full Text] [Related]

  • 16. Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models.
    Lucattelli M, Bartalesi B, Cavarra E, Fineschi S, Lunghi B, Martorana PA, Lungarella G.
    Respir Res; 2005 Jul 26; 6(1):83. PubMed ID: 16045796
    [Abstract] [Full Text] [Related]

  • 17. Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: increase of cell-associated SLPI by neutrophil elastase.
    van Wetering S, van der Linden AC, van Sterkenburg MA, Rabe KF, Schalkwijk J, Hiemstra PS.
    J Investig Med; 2000 Sep 26; 48(5):359-66. PubMed ID: 10979241
    [Abstract] [Full Text] [Related]

  • 18. Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population.
    de Santi MM, Martorana PA, Cavarra E, Lungarella G.
    Lab Invest; 1995 Jul 26; 73(1):40-7. PubMed ID: 7603039
    [Abstract] [Full Text] [Related]

  • 19. Intratracheally-instilled antileukoprotease and alpha 1-proteinase inhibitor: effect on human neutrophil elastase-induced experimental emphysema and pulmonary localization.
    Rudolphus A, Kramps JA, Mauve I, Dijkman JH.
    Histochem J; 1994 Oct 26; 26(10):817-24. PubMed ID: 7883591
    [Abstract] [Full Text] [Related]

  • 20. AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase.
    Stevens T, Ekholm K, Gränse M, Lindahl M, Kozma V, Jungar C, Ottosson T, Falk-Håkansson H, Churg A, Wright JL, Lal H, Sanfridson A.
    J Pharmacol Exp Ther; 2011 Oct 26; 339(1):313-20. PubMed ID: 21791628
    [Abstract] [Full Text] [Related]

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