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Journal Abstract Search

578 related items for PubMed ID: 17496166

  • 21. C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists.
    Chao J, Taveras AG, Chao J, Aki C, Dwyer M, Yu Y, Purakkattle B, Rindgen D, Jakway J, Hipkin W, Fosetta J, Fan X, Lundell D, Fine J, Minnicozzi M, Phillips J, Merritt JR.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3778-83. PubMed ID: 17459706
    [Abstract] [Full Text] [Related]

  • 22. The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases.
    Russo RC, Garcia CC, Teixeira MM, Amaral FA.
    Expert Rev Clin Immunol; 2014 May 01; 10(5):593-619. PubMed ID: 24678812
    [Abstract] [Full Text] [Related]

  • 23. Administration of a CXC Chemokine Receptor 2 (CXCR2) Antagonist, SCH527123, Together with Oseltamivir Suppresses NETosis and Protects Mice from Lethal Influenza and Piglets from Swine-Influenza Infection.
    Ashar HK, Pulavendran S, Rudd JM, Maram P, Achanta M, Chow VTK, Malayer JR, Snider TA, Teluguakula N.
    Am J Pathol; 2021 Apr 01; 191(4):669-685. PubMed ID: 33453177
    [Abstract] [Full Text] [Related]

  • 24. SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects.
    Holz O, Khalilieh S, Ludwig-Sengpiel A, Watz H, Stryszak P, Soni P, Tsai M, Sadeh J, Magnussen H.
    Eur Respir J; 2010 Mar 01; 35(3):564-70. PubMed ID: 19643947
    [Abstract] [Full Text] [Related]

  • 25. Intracellular trafficking of human CXCR1 and CXCR2: regulation by receptor domains and actin-related kinases.
    Matityahu E, Feniger-Barish R, Meshel T, Zaslaver A, Ben-Baruch A.
    Eur J Immunol; 2002 Dec 01; 32(12):3525-35. PubMed ID: 12442335
    [Abstract] [Full Text] [Related]

  • 26. Differential cross-regulation of the human chemokine receptors CXCR1 and CXCR2. Evidence for time-dependent signal generation.
    Richardson RM, Pridgen BC, Haribabu B, Ali H, Snyderman R.
    J Biol Chem; 1998 Sep 11; 273(37):23830-6. PubMed ID: 9726994
    [Abstract] [Full Text] [Related]

  • 27. Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis.
    Hipkin RW, Deno G, Fine J, Sun Y, Wilburn B, Fan X, Gonsiorek W, Wiekowski MT.
    J Pharmacol Exp Ther; 2004 Jul 11; 310(1):291-300. PubMed ID: 15028780
    [Abstract] [Full Text] [Related]

  • 28. Actin filaments are involved in the regulation of trafficking of two closely related chemokine receptors, CXCR1 and CXCR2.
    Zaslaver A, Feniger-Barish R, Ben-Baruch A.
    J Immunol; 2001 Jan 15; 166(2):1272-84. PubMed ID: 11145710
    [Abstract] [Full Text] [Related]

  • 29. CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner.
    Cohen-Hillel E, Yron I, Meshel T, Soria G, Attal H, Ben-Baruch A.
    Cytokine; 2006 Jan 07; 33(1):1-16. PubMed ID: 16406804
    [Abstract] [Full Text] [Related]

  • 30. Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor.
    Bertini R, Barcelos LS, Beccari AR, Cavalieri B, Moriconi A, Bizzarri C, Di Benedetto P, Di Giacinto C, Gloaguen I, Galliera E, Corsi MM, Russo RC, Andrade SP, Cesta MC, Nano G, Aramini A, Cutrin JC, Locati M, Allegretti M, Teixeira MM.
    Br J Pharmacol; 2012 Jan 07; 165(2):436-54. PubMed ID: 21718305
    [Abstract] [Full Text] [Related]

  • 31. Identification and characterization of a new interleukin-8 receptor in bovine species.
    Lahouassa H, Rainard P, Caraty A, Riollet C.
    Mol Immunol; 2008 Feb 07; 45(4):1153-64. PubMed ID: 17727952
    [Abstract] [Full Text] [Related]

  • 32. CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration.
    Zeng Y, Sun HR, Yu C, Lai Y, Liu XJ, Wu J, Chen HQ, Liu XH.
    Cytokine; 2011 Jan 07; 53(1):42-51. PubMed ID: 21036625
    [Abstract] [Full Text] [Related]

  • 33. Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor.
    de Kruijf P, van Heteren J, Lim HD, Conti PG, van der Lee MM, Bosch L, Ho KK, Auld D, Ohlmeyer M, Smit MJ, Wijkmans JC, Zaman GJ, Smit MJ, Leurs R.
    J Pharmacol Exp Ther; 2009 May 07; 329(2):783-90. PubMed ID: 19190236
    [Abstract] [Full Text] [Related]

  • 34. Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis.
    Bruno O, Brullo C, Bondavalli F, Schenone S, Ranise A, Arduino N, Bertolotto MB, Montecucco F, Ottonello L, Dallegri F, Tognolini M, Ballabeni V, Bertoni S, Barocelli E.
    J Med Chem; 2007 Jul 26; 50(15):3618-26. PubMed ID: 17608466
    [Abstract] [Full Text] [Related]

  • 35. CXCL8((3-73))K11R/G31P antagonizes ligand binding to the neutrophil CXCR1 and CXCR2 receptors and cellular responses to CXCL8/IL-8.
    Li F, Zhang X, Gordon JR.
    Biochem Biophys Res Commun; 2002 May 10; 293(3):939-44. PubMed ID: 12051749
    [Abstract] [Full Text] [Related]

  • 36. Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2.
    Maeda DY, Peck AM, Schuler AD, Quinn MT, Kirpotina LN, Wicomb WN, Fan GH, Zebala JA.
    J Med Chem; 2014 Oct 23; 57(20):8378-97. PubMed ID: 25254640
    [Abstract] [Full Text] [Related]

  • 37. Interruption of G protein-coupling in CXCR2 does not alter ligand binding, but eliminates ligand-activation of GTPgamma35S binding, calcium mobilization, and chemotaxis.
    Yang W, Schraw WP, Mueller SG, Richmond A.
    Biochemistry; 1997 Dec 09; 36(49):15193-200. PubMed ID: 9398246
    [Abstract] [Full Text] [Related]

  • 38. Human T lymphocytes and mast cells differentially express and regulate extra- and intracellular CXCR1 and CXCR2.
    Lippert U, Zachmann K, Henz BM, Neumann C.
    Exp Dermatol; 2004 Aug 09; 13(8):520-5. PubMed ID: 15265017
    [Abstract] [Full Text] [Related]

  • 39. A common intracellular allosteric binding site for antagonists of the CXCR2 receptor.
    Salchow K, Bond ME, Evans SC, Press NJ, Charlton SJ, Hunt PA, Bradley ME.
    Br J Pharmacol; 2010 Apr 09; 159(7):1429-39. PubMed ID: 20233217
    [Abstract] [Full Text] [Related]

  • 40. Expression of chemokine receptors CXCR1 and CXCR2 during cardiopulmonary bypass.
    Chishti AD, Dark JH, Kesteven P, Powell H, Snowden C, Shenton BK, Kirby JA, Baudouin SV.
    J Thorac Cardiovasc Surg; 2001 Dec 09; 122(6):1162-6. PubMed ID: 11726891
    [Abstract] [Full Text] [Related]

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