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1045 related items for PubMed ID: 17496923

  • 21. Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.
    Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR.
    Biochemistry; 2005 Aug 16; 44(32):10784-95. PubMed ID: 16086581
    [Abstract] [Full Text] [Related]

  • 22. Integrating signals from RTKs to ERK/MAPK.
    McKay MM, Morrison DK.
    Oncogene; 2007 May 14; 26(22):3113-21. PubMed ID: 17496910
    [Abstract] [Full Text] [Related]

  • 23. 1Alpha,25-dihydroxyvitamin D3-mediated stimulation of steroid sulphatase activity in myeloid leukaemic cell lines requires VDRnuc-mediated activation of the RAS/RAF/ERK-MAP kinase signalling pathway.
    Hughes PJ, Brown G.
    J Cell Biochem; 2006 Jun 01; 98(3):590-617. PubMed ID: 16440327
    [Abstract] [Full Text] [Related]

  • 24. Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity.
    Lue H, Kapurniotu A, Fingerle-Rowson G, Roger T, Leng L, Thiele M, Calandra T, Bucala R, Bernhagen J.
    Cell Signal; 2006 May 01; 18(5):688-703. PubMed ID: 16122907
    [Abstract] [Full Text] [Related]

  • 25. MEK and RAF inhibitors for BRAF-mutated cancers.
    Belden S, Flaherty KT.
    Expert Rev Mol Med; 2012 Oct 12; 14():e17. PubMed ID: 23058743
    [Abstract] [Full Text] [Related]

  • 26. Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling.
    Repasky GA, Zhou Y, Morita S, Der CJ.
    Mol Carcinog; 2007 Dec 12; 46(12):958-70. PubMed ID: 17477350
    [Abstract] [Full Text] [Related]

  • 27. Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure.
    Kramer BW, Götz R, Rapp UR.
    BMC Cancer; 2004 Jun 01; 4():24. PubMed ID: 15171791
    [Abstract] [Full Text] [Related]

  • 28. Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway.
    Li LB, Goleva E, Hall CF, Ou LS, Leung DY.
    J Allergy Clin Immunol; 2004 Nov 01; 114(5):1059-69. PubMed ID: 15536411
    [Abstract] [Full Text] [Related]

  • 29. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway.
    Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G.
    Cancer Res; 2007 Jan 01; 67(1):289-99. PubMed ID: 17210710
    [Abstract] [Full Text] [Related]

  • 30. Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.
    Marampon F, Ciccarelli C, Zani BM.
    Mol Cancer; 2006 Aug 09; 5():31. PubMed ID: 16899113
    [Abstract] [Full Text] [Related]

  • 31. Development and implementation of three mitogen-activated protein kinase (MAPK) signaling pathway imaging assays to provide MAPK module selectivity profiling for kinase inhibitors: MK2-EGFP translocation, c-Jun, and ERK activation.
    Nickischer D, Laethem C, Trask OJ, Williams RG, Kandasamy R, Johnston PA, Johnston PA.
    Methods Enzymol; 2006 Aug 09; 414():389-418. PubMed ID: 17110204
    [Abstract] [Full Text] [Related]

  • 32. Sensitivity of normal, paramalignant, and malignant human urothelial cells to inhibitors of the epidermal growth factor receptor signaling pathway.
    MacLaine NJ, Wood MD, Holder JC, Rees RW, Southgate J.
    Mol Cancer Res; 2008 Jan 09; 6(1):53-63. PubMed ID: 18234962
    [Abstract] [Full Text] [Related]

  • 33. Targeting the ERK signaling pathway in cancer therapy.
    Kohno M, Pouyssegur J.
    Ann Med; 2006 Jan 09; 38(3):200-11. PubMed ID: 16720434
    [Abstract] [Full Text] [Related]

  • 34. Suppression of the Raf/MEK/ERK signaling cascade and inhibition of angiogenesis by the carboxyl terminus of angiopoietin-like protein 4.
    Yang YH, Wang Y, Lam KS, Yau MH, Cheng KK, Zhang J, Zhu W, Wu D, Xu A.
    Arterioscler Thromb Vasc Biol; 2008 May 09; 28(5):835-40. PubMed ID: 18340008
    [Abstract] [Full Text] [Related]

  • 35.
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  • 36. Coordinating ERK/MAPK signalling through scaffolds and inhibitors.
    Kolch W.
    Nat Rev Mol Cell Biol; 2005 Nov 09; 6(11):827-37. PubMed ID: 16227978
    [Abstract] [Full Text] [Related]

  • 37. Second nature: biological functions of the Raf-1 "kinase".
    Baccarini M.
    FEBS Lett; 2005 Jun 13; 579(15):3271-7. PubMed ID: 15943972
    [Abstract] [Full Text] [Related]

  • 38. The EGF receptor activates ERK but not JNK Ras-dependently in basal conditions but ERK and JNK activation pathways are predominantly Ras-independent during cardiomyocyte stretch.
    Duquesnes N, Vincent F, Morel E, Lezoualc'h F, Crozatier B.
    Int J Biochem Cell Biol; 2009 May 13; 41(5):1173-81. PubMed ID: 19015044
    [Abstract] [Full Text] [Related]

  • 39. RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade.
    Pleschka S.
    Biol Chem; 2008 Oct 13; 389(10):1273-82. PubMed ID: 18713014
    [Abstract] [Full Text] [Related]

  • 40. Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways.
    Dobbin E, Graham C, Corrigan PM, Thomas KG, Freeburn RW, Wheadon H.
    Exp Hematol; 2009 Jan 13; 37(1):111-121. PubMed ID: 19100521
    [Abstract] [Full Text] [Related]

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