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255 related items for PubMed ID: 17502120

  • 1. Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors.
    Dubois L, Douma K, Supuran CT, Chiu RK, van Zandvoort MA, Pastoreková S, Scozzafava A, Wouters BG, Lambin P.
    Radiother Oncol; 2007 Jun; 83(3):367-73. PubMed ID: 17502120
    [Abstract] [Full Text] [Related]

  • 2. Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model.
    Dubois L, Lieuwes NG, Maresca A, Thiry A, Supuran CT, Scozzafava A, Wouters BG, Lambin P.
    Radiother Oncol; 2009 Sep; 92(3):423-8. PubMed ID: 19616332
    [Abstract] [Full Text] [Related]

  • 3. Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.
    Said HM, Hagemann C, Carta F, Katzer A, Polat B, Staab A, Scozzafava A, Anacker J, Vince GH, Flentje M, Supuran CT.
    Bioorg Med Chem; 2013 Jul 01; 21(13):3949-57. PubMed ID: 23706268
    [Abstract] [Full Text] [Related]

  • 4. Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.
    Svastová E, Hulíková A, Rafajová M, Zat'ovicová M, Gibadulinová A, Casini A, Cecchi A, Scozzafava A, Supuran CT, Pastorek J, Pastoreková S.
    FEBS Lett; 2004 Nov 19; 577(3):439-45. PubMed ID: 15556624
    [Abstract] [Full Text] [Related]

  • 5. Induction by hypoxia combined with low glucose or low bicarbonate and high posttranslational stability upon reoxygenation contribute to carbonic anhydrase IX expression in cancer cells.
    Rafajová M, Zatovicová M, Kettmann R, Pastorek J, Pastoreková S.
    Int J Oncol; 2004 Apr 19; 24(4):995-1004. PubMed ID: 15010840
    [Abstract] [Full Text] [Related]

  • 6. Characterization of carbonic anhydrase IX (CA IX) as an endogenous marker of chronic hypoxia in live human tumor cells.
    Vordermark D, Kaffer A, Riedl S, Katzer A, Flentje M.
    Int J Radiat Oncol Biol Phys; 2005 Mar 15; 61(4):1197-207. PubMed ID: 15752902
    [Abstract] [Full Text] [Related]

  • 7. Rapid detection of the hypoxia-regulated CA-IX and NDRG1 gene expression in different glioblastoma cells in vitro.
    Said HM, Polat B, Staab A, Hagemann C, Stein S, Flentje M, Theobald M, Katzer A, Vordermark D.
    Oncol Rep; 2008 Aug 15; 20(2):413-9. PubMed ID: 18636206
    [Abstract] [Full Text] [Related]

  • 8. Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.
    Cecchi A, Hulikova A, Pastorek J, Pastoreková S, Scozzafava A, Winum JY, Montero JL, Supuran CT.
    J Med Chem; 2005 Jul 28; 48(15):4834-41. PubMed ID: 16033263
    [Abstract] [Full Text] [Related]

  • 9. Expression Dynamics of CA IX Epitope in Cancer Cells under Intermittent Hypoxia Correlates with Extracellular pH Drop and Cell Killing by Ureido-Sulfonamide CA IX Inhibitors.
    Sufian MA, Zamanova S, Shabana AM, Kemp B, Mondal UK, Supuran CT, Ilies MA.
    Int J Mol Sci; 2023 Feb 27; 24(5):. PubMed ID: 36902027
    [Abstract] [Full Text] [Related]

  • 10. Src induces expression of carbonic anhydrase IX via hypoxia-inducible factor 1.
    Takacova M, Holotnakova T, Barathova M, Pastorekova S, Kopacek J, Pastorek J.
    Oncol Rep; 2010 Mar 27; 23(3):869-74. PubMed ID: 20127031
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis.
    Yu SJ, Yoon JH, Lee JH, Myung SJ, Jang ES, Kwak MS, Cho EJ, Jang JJ, Kim YJ, Lee HS.
    Acta Pharmacol Sin; 2011 Jul 27; 32(7):912-20. PubMed ID: 21666701
    [Abstract] [Full Text] [Related]

  • 12. Distinct patterns of hypoxic expression of carbonic anhydrase IX (CA IX) in human malignant glioma cell lines.
    Said HM, Staab A, Hagemann C, Vince GH, Katzer A, Flentje M, Vordermark D.
    J Neurooncol; 2007 Jan 27; 81(1):27-38. PubMed ID: 16944313
    [Abstract] [Full Text] [Related]

  • 13. Binding of carbonic anhydrase IX to 45S rDNA genes is prevented by exportin-1 in hypoxic cells.
    Sasso E, Vitale M, Monteleone F, Boffo FL, Santoriello M, Sarnataro D, Garbi C, Sabatella M, Crifò B, Paolella LA, Minopoli G, Winum JY, Zambrano N.
    Biomed Res Int; 2015 Jan 27; 2015():674920. PubMed ID: 25793203
    [Abstract] [Full Text] [Related]

  • 14. High cell density-mediated pericellular hypoxia is a crucial factor inducing expression of the intrinsic hypoxia marker CA IX in vitro in HeLa cells.
    Chrastina A.
    Neoplasma; 2003 Jan 27; 50(4):251-6. PubMed ID: 12937836
    [Abstract] [Full Text] [Related]

  • 15. Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment.
    Perut F, Carta F, Bonuccelli G, Grisendi G, Di Pompo G, Avnet S, Sbrana FV, Hosogi S, Dominici M, Kusuzaki K, Supuran CT, Baldini N.
    Expert Opin Ther Targets; 2015 Jan 27; 19(12):1593-605. PubMed ID: 26357839
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia.
    Tafreshi NK, Lloyd MC, Proemsey JB, Bui MM, Kim J, Gillies RJ, Morse DL.
    Mol Imaging Biol; 2016 Apr 27; 18(2):219-31. PubMed ID: 26276155
    [Abstract] [Full Text] [Related]

  • 17. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.
    Puccetti L, Fasolis G, Cecchi A, Winum JY, Gamberi A, Montero JL, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2005 May 02; 15(9):2359-64. PubMed ID: 15837325
    [Abstract] [Full Text] [Related]

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  • 19. Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX.
    Takacova M, Holotnakova T, Vondracek J, Machala M, Pencikova K, Gradin K, Poellinger L, Pastorek J, Pastorekova S, Kopacek J.
    Biochem J; 2009 Apr 15; 419(2):419-25. PubMed ID: 19154183
    [Abstract] [Full Text] [Related]

  • 20. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer.
    Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ.
    J Clin Oncol; 2003 Feb 01; 21(3):473-82. PubMed ID: 12560438
    [Abstract] [Full Text] [Related]

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