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144 related items for PubMed ID: 17503381

  • 1. Development of an approach for ab initio estimation of compound-induced liver injury based on global gene transcriptional profiles.
    Dai X, He YD, Dai H, Lum PY, Roberts CJ, Waring JF, Ulrich RG.
    Genome Inform; 2006; 17(2):77-88. PubMed ID: 17503381
    [Abstract] [Full Text] [Related]

  • 2. Acute hepatotoxicity: a predictive model based on focused illumina microarrays.
    Zidek N, Hellmann J, Kramer PJ, Hewitt PG.
    Toxicol Sci; 2007 Sep; 99(1):289-302. PubMed ID: 17522070
    [Abstract] [Full Text] [Related]

  • 3. Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers.
    Thukral SK, Nordone PJ, Hu R, Sullivan L, Galambos E, Fitzpatrick VD, Healy L, Bass MB, Cosenza ME, Afshari CA.
    Toxicol Pathol; 2005 Sep; 33(3):343-55. PubMed ID: 15805072
    [Abstract] [Full Text] [Related]

  • 4. Assessing chronic liver toxicity based on relative gene expression data.
    Kulkarni K, Larsen P, Linninger AA.
    J Theor Biol; 2008 Sep 21; 254(2):308-18. PubMed ID: 18585395
    [Abstract] [Full Text] [Related]

  • 5. Identification of potential genomic biomarkers of hepatotoxicity caused by reactive metabolites of N-methylformamide: Application of stable isotope labeled compounds in toxicogenomic studies.
    Mutlib A, Jiang P, Atherton J, Obert L, Kostrubsky S, Madore S, Nelson S.
    Chem Res Toxicol; 2006 Oct 21; 19(10):1270-83. PubMed ID: 17040096
    [Abstract] [Full Text] [Related]

  • 6. Simultaneous measurement of gene expression for hepatotoxicity in thioacetamide-administered rats by DNA microarrays.
    Minami K, Maniratanachote R, Katoh M, Nakajima M, Yokoi T.
    Mutat Res; 2006 Jan 31; 603(1):64-73. PubMed ID: 16337175
    [Abstract] [Full Text] [Related]

  • 7. Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.
    Kienhuis AS, Wortelboer HM, Hoflack JC, Moonen EJ, Kleinjans JC, van Ommen B, van Delft JH, Stierum RH.
    Drug Metab Dispos; 2006 Dec 31; 34(12):2083-90. PubMed ID: 16963487
    [Abstract] [Full Text] [Related]

  • 8. Time- and dose-based gene expression profiles produced by a bile-duct-damaging chemical, 4,4'-methylene dianiline, in mouse liver in an acute phase.
    Kwon SB, Park JS, Yi JY, Hwang JW, Kim M, Lee MO, Lee BH, Kim HL, Kim JH, Chung H, Kong G, Kang KS, Yoon BI.
    Toxicol Pathol; 2008 Jul 31; 36(5):660-73. PubMed ID: 18648102
    [Abstract] [Full Text] [Related]

  • 9. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
    Ebbels TM, Keun HC, Beckonert OP, Bollard ME, Lindon JC, Holmes E, Nicholson JK.
    J Proteome Res; 2007 Nov 31; 6(11):4407-22. PubMed ID: 17915905
    [Abstract] [Full Text] [Related]

  • 10. Oral administration of diphenyl diselenide potentiates hepatotoxicity induced by carbon tetrachloride in rats.
    Nogueira CW, Borges LP, Souza AC.
    J Appl Toxicol; 2009 Mar 31; 29(2):156-64. PubMed ID: 18989868
    [Abstract] [Full Text] [Related]

  • 11. Predictive models of hepatotoxicity using gene expression data from primary rat hepatocytes.
    Hultin-Rosenberg L, Jagannathan S, Nilsson KC, Matis SA, Sjögren N, Huby RD, Salter AH, Tugwood JD.
    Xenobiotica; 2006 Mar 31; 36(10-11):1122-39. PubMed ID: 17118920
    [Abstract] [Full Text] [Related]

  • 12. A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity.
    Fielden MR, Eynon BP, Natsoulis G, Jarnagin K, Banas D, Kolaja KL.
    Toxicol Pathol; 2005 Mar 31; 33(6):675-83. PubMed ID: 16239200
    [Abstract] [Full Text] [Related]

  • 13. Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database.
    Kondo C, Minowa Y, Uehara T, Okuno Y, Nakatsu N, Ono A, Maruyama T, Kato I, Yamate J, Yamada H, Ohno Y, Urushidani T.
    Toxicology; 2009 Nov 09; 265(1-2):15-26. PubMed ID: 19761811
    [Abstract] [Full Text] [Related]

  • 14. Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes.
    Elferink MG, Olinga P, van Leeuwen EM, Bauerschmidt S, Polman J, Schoonen WG, Heisterkamp SH, Groothuis GM.
    Toxicol Appl Pharmacol; 2011 May 15; 253(1):57-69. PubMed ID: 21420995
    [Abstract] [Full Text] [Related]

  • 15. Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils.
    Waring JF, Liguori MJ, Luyendyk JP, Maddox JF, Ganey PE, Stachlewitz RF, North C, Blomme EA, Roth RA.
    J Pharmacol Exp Ther; 2006 Mar 15; 316(3):1080-7. PubMed ID: 16299187
    [Abstract] [Full Text] [Related]

  • 16. Scoring multiple toxicological endpoints using a toxicogenomic database.
    Kiyosawa N, Ando Y, Watanabe K, Niino N, Manabe S, Yamoto T.
    Toxicol Lett; 2009 Jul 24; 188(2):91-7. PubMed ID: 19446240
    [Abstract] [Full Text] [Related]

  • 17. Gene expression profiling in rat liver treated with compounds inducing phospholipidosis.
    Hirode M, Ono A, Miyagishima T, Nagao T, Ohno Y, Urushidani T.
    Toxicol Appl Pharmacol; 2008 Jun 15; 229(3):290-9. PubMed ID: 18355885
    [Abstract] [Full Text] [Related]

  • 18. Validation of putative genomic biomarkers of nephrotoxicity in rats.
    Wang EJ, Snyder RD, Fielden MR, Smith RJ, Gu YZ.
    Toxicology; 2008 Apr 18; 246(2-3):91-100. PubMed ID: 18289764
    [Abstract] [Full Text] [Related]

  • 19. Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles.
    Waring JF, Jolly RA, Ciurlionis R, Lum PY, Praestgaard JT, Morfitt DC, Buratto B, Roberts C, Schadt E, Ulrich RG.
    Toxicol Appl Pharmacol; 2001 Aug 15; 175(1):28-42. PubMed ID: 11509024
    [Abstract] [Full Text] [Related]

  • 20. Gene expression profiling reveals multiple toxicity endpoints induced by hepatotoxicants.
    Huang Q, Jin X, Gaillard ET, Knight BL, Pack FD, Stoltz JH, Jayadev S, Blanchard KT.
    Mutat Res; 2004 May 18; 549(1-2):147-67. PubMed ID: 15120968
    [Abstract] [Full Text] [Related]

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