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PUBMED FOR HANDHELDS

Journal Abstract Search

136 related items for PubMed ID: 17503422

  • 1. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL.
    Sadowsky JD, Murray JK, Tomita Y, Gellman SH.
    Chembiochem; 2007 May 25; 8(8):903-16. PubMed ID: 17503422
    [Abstract] [Full Text] [Related]

  • 2. (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions.
    Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH.
    J Am Chem Soc; 2007 Jan 10; 129(1):139-54. PubMed ID: 17199293
    [Abstract] [Full Text] [Related]

  • 3. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition.
    Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH.
    J Am Chem Soc; 2005 Aug 31; 127(34):11966-8. PubMed ID: 16117535
    [Abstract] [Full Text] [Related]

  • 4. Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis.
    Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH.
    J Comb Chem; 2008 Aug 31; 10(2):204-15. PubMed ID: 18275161
    [Abstract] [Full Text] [Related]

  • 5. Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics.
    Peterson-Kaufman KJ, Haase HS, Boersma MD, Lee EF, Fairlie WD, Gellman SH.
    ACS Chem Biol; 2015 Jul 17; 10(7):1667-75. PubMed ID: 25946900
    [Abstract] [Full Text] [Related]

  • 6. Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent.
    Modi V, Lama D, Sankararamakrishnan R.
    J Biomol Struct Dyn; 2013 Jul 17; 31(1):65-77. PubMed ID: 22803956
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain.
    Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH.
    J Am Chem Soc; 2012 Jan 11; 134(1):315-23. PubMed ID: 22040025
    [Abstract] [Full Text] [Related]

  • 8. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.
    Yin H, Lee GI, Sedey KA, Kutzki O, Park HS, Orner BP, Ernst JT, Wang HG, Sebti SM, Hamilton AD.
    J Am Chem Soc; 2005 Jul 27; 127(29):10191-6. PubMed ID: 16028929
    [Abstract] [Full Text] [Related]

  • 9. Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.
    Zhang YH, Bhunia A, Wan KF, Lee MC, Chan SL, Yu VC, Mok YK.
    J Mol Biol; 2006 Dec 01; 364(3):536-49. PubMed ID: 17011577
    [Abstract] [Full Text] [Related]

  • 10. Amino acid requirement for the high affinity binding of a selected arginine-rich peptide with the HIV Rev-response element RNA.
    Sugaya M, Nishino N, Katoh A, Harada K.
    J Pept Sci; 2008 Aug 01; 14(8):924-35. PubMed ID: 18351707
    [Abstract] [Full Text] [Related]

  • 11. A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein.
    Feng Y, Zhang L, Hu T, Shen X, Ding J, Chen K, Jiang H, Liu D.
    Arch Biochem Biophys; 2009 Apr 01; 484(1):46-54. PubMed ID: 19161970
    [Abstract] [Full Text] [Related]

  • 12. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL.
    Kneissl S, Loveridge EJ, Williams C, Crump MP, Allemann RK.
    Chembiochem; 2008 Dec 15; 9(18):3046-54. PubMed ID: 19012295
    [Abstract] [Full Text] [Related]

  • 13. Structural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design.
    Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD.
    Chembiochem; 2011 Sep 05; 12(13):2025-32. PubMed ID: 21744457
    [Abstract] [Full Text] [Related]

  • 14. Structure-activity relationships of Bak derived peptides: affinity and specificity modulations by amino acid replacement.
    Frey V, Viaud J, Subra G, Cauquil N, Guichou JF, Casara P, Grassy G, Chavanieu A.
    Eur J Med Chem; 2008 May 05; 43(5):966-72. PubMed ID: 17692431
    [Abstract] [Full Text] [Related]

  • 15. α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells.
    Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, Eller CH, Raines RT, Murphy WL, Smith BJ, Gellman SH, Fairlie WD.
    J Am Chem Soc; 2015 Sep 09; 137(35):11365-75. PubMed ID: 26317395
    [Abstract] [Full Text] [Related]

  • 16. Residue-based control of helix shape in beta-peptide oligomers.
    Appella DH, Christianson LA, Klein DA, Powell DR, Huang X, Barchi JJ, Gellman SH.
    Nature; 1997 May 22; 387(6631):381-4. PubMed ID: 9163422
    [Abstract] [Full Text] [Related]

  • 17. Protein design with L- and D-alpha-amino acid structures as the alphabet.
    Durani S.
    Acc Chem Res; 2008 Oct 22; 41(10):1301-8. PubMed ID: 18642934
    [Abstract] [Full Text] [Related]

  • 18. New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns.
    Schmitt MA, Choi SH, Guzei IA, Gellman SH.
    J Am Chem Soc; 2006 Apr 12; 128(14):4538-9. PubMed ID: 16594667
    [Abstract] [Full Text] [Related]

  • 19. Alpha-aminoxy acids: new possibilities from foldamers to anion receptors and channels.
    Li X, Wu YD, Yang D.
    Acc Chem Res; 2008 Oct 12; 41(10):1428-38. PubMed ID: 18785763
    [Abstract] [Full Text] [Related]

  • 20. The proteolytic stability and cytotoxicity studies of L-aspartic acid and L-diaminopropionic acid derived beta-peptides and a mixed alpha/beta-peptide.
    Ahmed S, Kaur K.
    Chem Biol Drug Des; 2009 May 12; 73(5):545-52. PubMed ID: 19317848
    [Abstract] [Full Text] [Related]

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