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Journal Abstract Search

188 related items for PubMed ID: 17519385

  • 1. Applicability of the dopamine and rate hypotheses in explaining the differences in behavioral pharmacology of the chloro-benztropine analogs: studies conducted using intracerebral microdialysis and population pharmacodynamic modeling.
    Othman AA, Newman AH, Eddington ND.
    J Pharmacol Exp Ther; 2007 Aug; 322(2):760-9. PubMed ID: 17519385
    [Abstract] [Full Text] [Related]

  • 2. Behavioral and neurochemical effects of the dopamine transporter ligand 4-chlorobenztropine alone and in combination with cocaine in vivo.
    Tolliver BK, Newman AH, Katz JL, Ho LB, Fox LM, Hsu K, Berger SP.
    J Pharmacol Exp Ther; 1999 Apr; 289(1):110-22. PubMed ID: 10086994
    [Abstract] [Full Text] [Related]

  • 3. Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling.
    Raje S, Cornish J, Newman AH, Cao J, Katz JL, Eddington ND.
    Pharm Res; 2005 Apr; 22(4):603-12. PubMed ID: 15846468
    [Abstract] [Full Text] [Related]

  • 4. 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Kline RH, Izenwasser S, Katz JL, Joseph DB, Bowen WD, Newman AH.
    J Med Chem; 1997 Mar 14; 40(6):851-7. PubMed ID: 9083473
    [Abstract] [Full Text] [Related]

  • 5. Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse.
    Othman AA, Syed SA, Newman AH, Eddington ND.
    J Pharmacol Exp Ther; 2007 Jan 14; 320(1):344-53. PubMed ID: 17003230
    [Abstract] [Full Text] [Related]

  • 6. Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.
    Katz JL, Agoston GE, Alling KL, Kline RH, Forster MJ, Woolverton WL, Kopajtic TA, Newman AH.
    Psychopharmacology (Berl); 2001 Apr 14; 154(4):362-74. PubMed ID: 11349389
    [Abstract] [Full Text] [Related]

  • 7. Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change.
    Tanda G, Li SM, Mereu M, Thomas AM, Ebbs AL, Chun LE, Tronci V, Green JL, Zou MF, Kopajtic TA, Newman AH, Katz JL.
    Psychopharmacology (Berl); 2013 Sep 14; 229(2):307-21. PubMed ID: 23612854
    [Abstract] [Full Text] [Related]

  • 8. Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine.
    Tanda G, Ebbs A, Newman AH, Katz JL.
    J Pharmacol Exp Ther; 2005 May 14; 313(2):613-20. PubMed ID: 15681658
    [Abstract] [Full Text] [Related]

  • 9. Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis.
    Raje S, Cornish J, Newman AH, Cao J, Katz JL, Eddington ND.
    Biopharm Drug Dispos; 2006 Jul 14; 27(5):229-40. PubMed ID: 16586462
    [Abstract] [Full Text] [Related]

  • 10. 3'- and 4'-chloro-substituted analogs of benztropine: intravenous self-administration and in vitro radioligand binding studies in rhesus monkeys.
    Woolverton WL, Rowlett JK, Wilcox KM, Paul IA, Kline RH, Newman AH, Katz JL.
    Psychopharmacology (Berl); 2000 Jan 14; 147(4):426-35. PubMed ID: 10672637
    [Abstract] [Full Text] [Related]

  • 11. Population pharmacokinetics, brain distribution, and pharmacodynamics of 2nd generation dopamine transporter selective benztropine analogs developed as potential substitute therapeutics for treatment of cocaine abuse.
    Syed SA, Newman AH, Othman AA, Eddington ND.
    J Pharm Sci; 2008 May 14; 97(5):1993-2007. PubMed ID: 17879975
    [Abstract] [Full Text] [Related]

  • 12. Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.
    Katz JL, Kopajtic TA, Agoston GE, Newman AH.
    J Pharmacol Exp Ther; 2004 May 14; 309(2):650-60. PubMed ID: 14755006
    [Abstract] [Full Text] [Related]

  • 13. Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs.
    Desai RI, Kopajtic TA, French D, Newman AH, Katz JL.
    J Pharmacol Exp Ther; 2005 Oct 14; 315(1):397-404. PubMed ID: 16014753
    [Abstract] [Full Text] [Related]

  • 14. Further studies of the reinforcing effects of benztropine analogs in rhesus monkeys.
    Woolverton WL, Hecht GS, Agoston GE, Katz JL, Newman AH.
    Psychopharmacology (Berl); 2001 Apr 14; 154(4):375-82. PubMed ID: 11349390
    [Abstract] [Full Text] [Related]

  • 15. Place conditioning and locomotor effects of N-substituted, 4',4''-difluorobenztropine analogs in rats.
    Li SM, Newman AH, Katz JL.
    J Pharmacol Exp Ther; 2005 Jun 14; 313(3):1223-30. PubMed ID: 15743929
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques.
    Raje S, Cao J, Newman AH, Gao H, Eddington ND.
    J Pharmacol Exp Ther; 2003 Nov 14; 307(2):801-8. PubMed ID: 12966155
    [Abstract] [Full Text] [Related]

  • 17. Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs.
    Campbell VC, Kopajtic TA, Newman AH, Katz JL.
    J Pharmacol Exp Ther; 2005 Nov 14; 315(2):631-40. PubMed ID: 16055673
    [Abstract] [Full Text] [Related]

  • 18. Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
    Chen N, Zhen J, Reith ME.
    J Neurochem; 2004 May 14; 89(4):853-64. PubMed ID: 15140185
    [Abstract] [Full Text] [Related]

  • 19. Therapeutic-like properties of a dopamine uptake inhibitor in animal models of amphetamine addiction.
    Velazquez-Sanchez C, Ferragud A, Renau-Piqueras J, Canales JJ.
    Int J Neuropsychopharmacol; 2011 Jun 14; 14(5):655-65. PubMed ID: 20735880
    [Abstract] [Full Text] [Related]

  • 20. Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors.
    Tanda G, Newman AH, Katz JL.
    Adv Pharmacol; 2009 Jun 14; 57():253-89. PubMed ID: 20230764
    [Abstract] [Full Text] [Related]

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